Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mustafa Tugrul Goktas"'
Publikováno v:
Indian Journal of Pharmaceutical Education and Research. 51:741-746
WOS: 000435144400029
Background: Methotrexate (MTX) is one of the most commonly used chemotherapeutic agents in the treatment of cancer patients, however its therapeutic use is limited due to dose dependent hepatotoxicity caused by oxidative dam
Background: Methotrexate (MTX) is one of the most commonly used chemotherapeutic agents in the treatment of cancer patients, however its therapeutic use is limited due to dose dependent hepatotoxicity caused by oxidative dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecccdb497713a149bb9f40a5c8c4ba6
https://doi.org/10.5530/ijper.51.4s.107
https://doi.org/10.5530/ijper.51.4s.107
Autor:
Ragip Ozgur Karaca, Lokman Cevik, Mustafa Tugrul Goktas, Said Kalkisim, Levent Kilic, Ali Akdogan, Atilla Bozkurt, Umit Yasar, Melih O. Babaoglu, Leif Bertilsson
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 121:266-271
Behçet's disease (BD) is a systemic autoimmune disorder. Cytochrome P450 enzymes (CYPs) are responsible for various drug metabolism reactions as well as those of endogenous substances which may be associated with autoimmune disease susceptibility. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f06c142c68918c3ae48fb8f2f4af54e
https://doi.org/10.1111/bcpt.12710
https://doi.org/10.1111/bcpt.12710
Autor:
Hulagu Bariskaner, Mustafa Tugrul Goktas, Alper B. Iskit, Ceyhan Ugurluoglu, Aysun Toker, Erdem Kamil Ozer, Sultan Pehlivan
Publikováno v:
Pharmacological Reports. 69:683-690
Background Thymoquinone (TQ) is a potent cytoprotective, antioxidant and anti-inflammatory agent. We aimed to investigate the possible protective effects of TQ on survival, mesenteric artery blood flow (MABF), vascular reactivity, oxidative and infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676e8150b0613b74ddbb94325fc4e6f9
https://doi.org/10.1016/j.pharep.2017.02.021
https://doi.org/10.1016/j.pharep.2017.02.021
Autor:
Umit Yasar, Said Kalkisim, Serta Kilincalp, Atilla Bozkurt, R. Özgür Karaca, İlhami Yüksel, Melih O. Babaoglu, Akif Altinbas, Mustafa Tugrul Goktas
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 120:199-206
Pantoprazole is a proton pump inhibitor that is commonly used in the treatment of peptic ulcer disease (PUD) and metabolized by cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4. Pantoprazole is a substrate for multi-drug resistance protein 1 (MDR1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7778b6f93da64a8be1e7be176a7c0db1
https://doi.org/10.1111/bcpt.12667
https://doi.org/10.1111/bcpt.12667
Autor:
R. Özgür Karaca, Melih O. Babaoglu, Ahmet Muderrisoglu, Nurhayat Eni, Gökhan Yoca, Yavuz Ayhan, A. Elif Anil Yağcioğlu, Mustafa Tugrul Goktas, Atilla Bozkurt, Lokman Cevik, M. Kâzım Yazıcı
Publikováno v:
Journal of Clinical Psychopharmacology. 36:257-261
Clozapine use is associated with leukopenia and more rarely agranulocytosis, which may be lethal. The drug and its metabolites are proposed to interact with the multidrug resistance transporter (ABCB1/MDR1) gene product, P-glycoprotein (P-gp). Among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d842b714106213df3f736674bb74a9
https://doi.org/10.1097/jcp.0000000000000495
https://doi.org/10.1097/jcp.0000000000000495
Autor:
Melih O. Babaoglu, Fazleen Haslinda Mohd Hatta, Ozgur Karaca, Anders Helldén, Ali Akdogan, Leif Bertilsson, Said Kalkisim, Mustafa Tugrul Goktas, Atilla Bozkurt, Levent Kilic, Umit Yasar
Publikováno v:
European Journal of Clinical Pharmacology. 71:1223-1228
We previously reported on a Swedish patient with Behcet’s disease (BD) who was an ultra-rapid metaboliser of drugs catalysed by CYP2C9. Was this extreme metabolism caused by the disease? This study aims to compare the genotype/phenotype of CYP2C9 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae08a13a959c3504b6b627f10962b75
https://doi.org/10.1007/s00228-015-1899-7
https://doi.org/10.1007/s00228-015-1899-7
Autor:
Ceyhan Ugurluoglu, Alper B. Iskit, Aysun Toker, Hulagu Bariskaner, Erdem Kamil Ozer, Mustafa Tugrul Goktas
Publikováno v:
Inflammation. 40(5)
Carvacrol (CRV) has strong cytoprotective, antioxidant, and anti-inflammatory properties. We aimed to demonstrate the possible protective effects of CRV on survival, mesenteric artery blood flow (MBF), vascular reactivity, and oxidative and inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba5f0da9f2e7470bac8a8f16a9c061c
https://pubmed.ncbi.nlm.nih.gov/28646428
https://pubmed.ncbi.nlm.nih.gov/28646428
Coenzyme Q10 improves the survival, mesenteric perfusion, organs and vessel functions in septic rats
Autor:
Alper B. Iskit, Erdem Kamil Ozer, Hulagu Bariskaner, Mustafa Tugrul Goktas, Ceyhan Ugurluoglu, Ibrahim Kilinc, Sultan Pehlivan
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 91
Background Coenzyme Q10 (CoQ10) is a naturally occurring, lipid-soluble antioxidant and an essential electron carrier in the mitochondrial respiratory chain. In sepsis, CoQ10 deficiency induced by mitochondrial failure can lead to hypoxia, hypoperfus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeba300b3a9531332fbb0b51d7a611a
https://pubmed.ncbi.nlm.nih.gov/28501779
https://pubmed.ncbi.nlm.nih.gov/28501779
Autor:
Ceyhan Ugurluoglu, Alper B. Iskit, Erdem Kamil Ozer, Hulagu Bariskaner, Mustafa Tugrul Goktas, Ibrahim Kilinc, Aysun Toker
WOS: 000404738500012
PubMed: 28459157
Tumor necrosis factor-alpha (TNF-alpha) is a pivotal mediator that triggers inflammatory process, oxidative stress, and multiple organ injury in sepsis. We investigated the effects of infliximab on surv
PubMed: 28459157
Tumor necrosis factor-alpha (TNF-alpha) is a pivotal mediator that triggers inflammatory process, oxidative stress, and multiple organ injury in sepsis. We investigated the effects of infliximab on surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5bfcc2700a044032a97eac98411919
https://hdl.handle.net/20.500.12395/35206
https://hdl.handle.net/20.500.12395/35206
Autor:
Mustafa Çelik, Hüseyin Üçer, Hamit Sırrı Keten, Ozgur Ersoy, Derya Keten, Mustafa Tugrul Goktas
Publikováno v:
Journal of Oral Pathology & Medicine. 44:502-506
Introduction The aim of this study was to investigate Candida carriage and species in Maras powder users and non-users. Material and Methods This study included 100 volunteering men in 12 cafes in the city of Kahramanmaras, Turkey. A questionnaire co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652c78c3be519572243cee21aca87b9e
https://doi.org/10.1111/jop.12260
https://doi.org/10.1111/jop.12260