Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mustafa M Munye"'
Autor:
Mustafa M Munye, Anna Diaz-Font, Louise Ocaka, Maiken L Henriksen, Melissa Lees, Angela Brady, Dagan Jenkins, Jenny Morton, Soren W Hansen, Chiara Bacchelli, Philip L Beales, Victor Hernandez-Hernandez
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006679 (2017)
3MC syndrome is an autosomal recessive heterogeneous disorder with features linked to developmental abnormalities. The main features include facial dysmorphism, craniosynostosis and cleft lip/palate; skeletal structures derived from cranial neural cr
Externí odkaz:
https://doaj.org/article/d4cff8dee67f4df98f85d62b08e48905
Autor:
Aristides D, Tagalakis, Vignesh, Jayarajan, Ruhina, Maeshima, Kin H, Ho, Farhatullah, Syed, Lin-Ping, Wu, Ahmad M, Aldossary, Mustafa M, Munye, Talisa, Mistry, Olumide Kayode, Ogunbiyi, Arturo, Sala, Joseph F, Standing, Seyed M, Moghimi, Andrew W, Stoker, Stephen L, Hart
Publikováno v:
Advanced functional materials. 31(37)
The authors aim to develop siRNA therapeutics for cancer that can be administered systemically to target tumors and retard their growth. The efficacy of systemic delivery of siRNA to tumors with nanoparticles based on lipids or polymers is often comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc27ac1195fc4326e0883ead95c8ca8d
https://pubmed.ncbi.nlm.nih.gov/35712226
https://pubmed.ncbi.nlm.nih.gov/35712226
Autor:
Lin-Ping Wu, Ahmad Aldossary, Stephen L. Hart, Olumide Ogunbiyi, Joseph F. Standing, Mustafa M. Munye, Talisa Mistry, Kin H. Ho, Aristides D. Tagalakis, Vignesh Jayarajan, Farhatullah Syed, Arturo Sala, Seyed Moein Moghimi, Ruhina Maeshima, Andrew W. Stoker
Publikováno v:
Advanced Functional Materials. 31:2104843
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9f7ddf4d45eed743a6bead39fbdeb1
https://doi.org/10.1002/adfm.202104843
https://doi.org/10.1002/adfm.202104843
Autor:
Rositsa, Ivanova, David C H, Benton, Mustafa M, Munye, Sarinda, Rangseesorranan, Stephen L, Hart, Guy W J, Moss
Publikováno v:
ACS applied materialsinterfaces. 11(9)
Ciliated lung epithelial cells and the airway surface liquid (ASL) comprise one of the body's most important protective systems. This system is finely tuned, and perturbations to ASL rheology, ASL depth, ASL pH, the transepithelial potential, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77538268b9ebb261424e625b6071a854
https://pubmed.ncbi.nlm.nih.gov/30648848
https://pubmed.ncbi.nlm.nih.gov/30648848
Autor:
Jenny Eichhorst, Maria Manunta, Stephen L. Hart, Alexander Weng, Burkhard Wiesner, Matthias F. Melzig, Ayad Eddaoudi, Mustafa M. Munye, Aristides D. Tagalakis, Roger Gilabert-Oriol, Conrad A. Vink, Mayank Thakur
Publikováno v:
Journal of Controlled Release. 206:75-90
Targeted nanocarriers undergo endocytosis upon binding to their membrane receptors and are transported into cellular compartments such as late endosomes and lysosomes. In gene delivery the genetic material has to escape from the cellular compartments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a2717b9f6f4dd30dce3f4229170928
https://doi.org/10.1016/j.jconrel.2015.03.007
https://doi.org/10.1016/j.jconrel.2015.03.007
Publikováno v:
Hematology/oncology clinics of North America. 31(5)
Gene delivery vectors that do not rely on host cell genome integration offer several advantages for gene transfer, chiefly the avoidance of insertional mutagenesis and position effect variegation. However, unless engineered for replication and segreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95739caacd5f93798c71b922939fdd8
https://pubmed.ncbi.nlm.nih.gov/28895845
https://pubmed.ncbi.nlm.nih.gov/28895845
Autor:
Aristides D, Tagalakis, Mustafa M, Munye, Rositsa, Ivanova, Hanpeng, Chen, Claire M, Smith, Ahmad M, Aldossary, Luca Z, Rosa, Dale, Moulding, Josephine L, Barnes, Konstantinos N, Kafetzis, Stuart A, Jones, Deborah L, Baines, Guy W J, Moss, Christopher, O'Callaghan, Robin J, McAnulty, Stephen L, Hart
Publikováno v:
Thorax
Introduction Loss of the cystic fibrosis transmembrane conductance regulator in cystic fibrosis (CF) leads to hyperabsorption of sodium and fluid from the airway due to upregulation of the epithelial sodium channel (ENaC). Thickened mucus and deplete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f38337f370d8198983f83c1b79ecf818
https://pubmed.ncbi.nlm.nih.gov/29748250
https://pubmed.ncbi.nlm.nih.gov/29748250
Autor:
David McCarthy, Marcella J Wyatt, Hannah Taylor, Stephen L. Hart, Mustafa M. Munye, Mark F. Lythgoe, Aristides D. Tagalakis, Alison Bienemann, Gavin D. Kenny, Edward White
Publikováno v:
Journal of Controlled Release. 174:177-187
Non-viral vector formulations comprise typically complexes of nucleic acids with cationic polymers or lipids. However, for in vivo applications cationic formulations suffer from problems of poor tissue penetration, non-specific binding to cells, inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0a989c64095454e351e93607b7acbf
Autor:
Mustafa M, Munye, Aristides D, Tagalakis, Josephine L, Barnes, Rachel E, Brown, Robin J, McAnulty, Steven J, Howe, Stephen L, Hart
Publikováno v:
Scientific Reports
Gene therapy for cystic fibrosis using non-viral, plasmid-based formulations has been the subject of intensive research for over two decades but a clinically viable product has yet to materialise in large part due to inefficient transgene expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be788f2f555817c289305e9689b0fe34
https://pubmed.ncbi.nlm.nih.gov/26975732
https://pubmed.ncbi.nlm.nih.gov/26975732
Autor:
Aristides D, Tagalakis, Sara, Castellaro, Haiyan, Zhou, Alison, Bienemann, Mustafa M, Munye, David, McCarthy, Edward A, White, Stephen L, Hart
Publikováno v:
International Journal of Nanomedicine
Nonviral gene and small interfering RNA (siRNA) delivery formulations are extensively used for biological and therapeutic research in cell culture experiments, but less so in in vivo and clinical research. Difficulties with formulating the nanopartic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98808225de8035dd7d6f4e36ed57e218
https://pubmed.ncbi.nlm.nih.gov/25878500
https://pubmed.ncbi.nlm.nih.gov/25878500