Výsledky vyhledávání - "Mustafa Kemal RUHI"

Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer †

Autor: Brittany P. Rickard, Marta Overchuk, Girgis Obaid, Mustafa Kemal Ruhi, Utkan Demirci, Suzanne E. Fenton, Janine H. Santos, David Kessel, Imran Rizvi

Publikováno v: Photochemistry and Photobiology. 99:448-468

Ovarian cancer is the most lethal gynecologic malignancy with a stubborn mortality rate of ~65%. The persistent failure of multiline chemotherapy, and significant tumor heterogeneity, has made it challenging to improve outcomes. A target of increasin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83df4be57d25428857b9a8a73a8997c8
https://doi.org/10.1111/php.13723

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Integrins in Ovarian Cancer: Survival Pathways, Malignant Ascites and Targeted Photochemistry

Autor: Mustafa Kemal Ruhi, Brittany P. Rickard, William J. Polacheck, Imran Rizvi

Publikováno v: Recent Advances, New Perspectives and Applications in the Treatment of Ovarian Cancer
Recent Advances, New Perspectives and Applications in the Treatment of Ovarian Cancer ISBN: 9781803565187

Integrins are surface adhesion molecules that, upon binding to ligands, cluster to form adhesion complexes. These adhesion complexes are comprised of structural and regulatory proteins that modulate a variety of cellular behaviors including different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc37ac83e25160638237406b085f0dc
https://mts.intechopen.com/articles/show/title/integrins-in-ovarian-cancer-survival-pathways-malignant-ascites-and-targeted-photochemistry

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Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer

Autor: Brittany P. Rickard, Marta Overchuk, Vesna A. Chappell, Mustafa Kemal Ruhi, Prima Dewi Sinawang, Tina Thuy Nguyen Hoang, Demir Akin, Utkan Demirci, Walfre Franco, Suzanne E. Fenton, Janine H. Santos, Imran Rizvi

Publikováno v: Cancers. 15:2564

Mitochondria are regulators of key cellular processes, including energy production and redox homeostasis. Mitochondrial dysfunction is associated with various human diseases, including cancer. Importantly, both structural and functional changes can a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cee6783345f665a5705133b2041acae
https://doi.org/10.3390/cancers15092564

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Targeted PDT Combinations to Overcome Fluid Shear Stress-induced Platinum Resistance in Ovarian Cancer

Autor: Marta OVERCHUK, Mustafa Kemal RUHI, Brittany RICKARD, Frances LIGLER, Imran RIZVI

Publikováno v: Photodiagnosis and Photodynamic Therapy. 41:103405

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20b21c77480daf3a05f99b1ba1d489ce
https://doi.org/10.1016/j.pdpdt.2023.103405

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Photodynamic Therapy and the Biophysics of the Tumor Microenvironment

Autor: Imran Rizvi, Nathaniel A. Ferlic, Mustafa Kemal Ruhi, William J. Polacheck, Vida Karimnia, Aaron J. Sorrin, Jonathan P. Celli, Huang-Chiao Huang

Publikováno v: Photochem Photobiol

Targeting the tumor microenvironment (TME) provides opportunities to modulate tumor physiology, enhance the delivery of therapeutic agents, impact immune response, and overcome resistance. Photodynamic therapy (PDT) is a photochemistry-based, non-the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb23dd7eb57c769dd9de60b55de31a91
https://doi.org/10.1111/php.13209

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A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer

Autor: Kaitlin Moore, Girgis Obaid, Mustafa Kemal Ruhi, Imran Rizvi, David Kessel, Shubhankar Nath, Tayyaba Hasan, Shazia Bano

Publikováno v: Photochemistry and Photobiology. 95:419-429

A major objective in developing new treatment approaches for lethal tumors is to reduce toxicity to normal tissues while maintaining therapeutic efficacy. Photodynamic therapy (PDT) provides a mechanistically distinct approach to treat tumors without

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973a36075798e90c96c0e660911e65e0
https://doi.org/10.1111/php.13066

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Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

Autor: William Hanna, Utkan Demirci, Imran Rizvi, Yujiro Tsujita, Huang-Chiao Huang, Walfre Franco, Marcela G. del Carmen, Fatih Inci, Amjad P. Khan, Karthik Pushpavanam, Jonathan P. Celli, Tayyaba Hasan, Kaitlin Moore, Mustafa Kemal Ruhi, Christina Conrad, Shubhankar Nath, Farzaneh MahmoodPoor Dehkordy, Michael Pigula, Kaushal Rege

Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 924, p 924 (2020)
Journal of Clinical Medicine
Volume 9
Issue 4

A key reason for the persistently grim statistics associated with metastatic ovarian cancer is resistance to conventional agents, including platinum-based chemotherapies. A major source of treatment failure is the high degree of genetic and molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042ad9cb041c23e7f977651fc627ae69
https://www.mdpi.com/2077-0383/9/4/924

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PC-3 Prostat Kanser Hücreleri Üzerinde İndosyanin Yeşili Kullanarak Yapılan Fotodinamik Terapinin AO/PI Boyama Testi Sonuçları

Autor: Ayşe Ak Can, Mustafa Kemal Ruhi, Murat Gulsoy

Publikováno v: Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Vol 22, Iss 1, Pp 182-185 (2018)
Volume: 22, Issue: 1 182-185
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi

Fotodinamik terapi (FDT) prostat kanseri tedavisinde henüz araştırma aşamasında olan sağaltıcı bir alternatiftir. FDT, ışığa duyarlı bir kimyasal maddenin (fotosensitizan) ışık ile aktive edilmesi ve aktive olan kimyasalın kanserli b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75eaa2ec0ea023aaffe909682f2aa03
http://dergipark.org.tr/sdufenbed/issue/37055/425692?publisher=sdu-1

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Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response

Autor: Dana M. Roque, Brittany P. Rickard, Stephanie Huang, Marcela G. del Carmen, William J. Polacheck, Giuliano Scarcelli, Imran Rizvi, Walfre Franco, Huang-Chiao Huang, Utkan Demirci, Jocelyn Reader, Aaron J. Sorrin, Christina Conrad, Mustafa Kemal Ruhi

Publikováno v: Cancers
Cancers, Vol 13, Iss 4318, p 4318 (2021)

Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or ascites, occurs more frequently in patients with advanced-stage ova

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a2db13a92161ddaf27c200d813a8b
https://doi.org/10.3390/cancers13174318

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Effect of Potassium Iodide Use on Anti-Cancer PDT Applications on PC-3 Prostate Cancer Cells

Autor: Merve Yunlu, Nermin Topaloglu, Mustafa Kemal Ruhi, Gunnur Onak

Publikováno v: 2019 Medical Technologies Congress (TIPTEKNO).

Photodynamic therapy (PDT) is a promising alternative method in the treatment of cancer. The mechanism of PDT is based on the production of reactive oxygen species (ROS) as a result of the interaction of the main components of molecular oxygen, light

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c0db3637238a6a9b0eea69463b84771
https://doi.org/10.1109/tiptekno.2019.8895107

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