Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Mustafa B. A. Djamgoz"'
Autor:
Peter Quicke, Yilin Sun, Mar Arias-Garcia, Melina Beykou, Corey D. Acker, Mustafa B. A. Djamgoz, Chris Bakal, Amanda J. Foust
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Voltage imaging and machine learning reveal that human breast cancer cells exhibit voltage fluctuations absent in non-tumorigenic breast cells, beginning to shed light on the bioelectric properties of cancer processes.
Externí odkaz:
https://doaj.org/article/e10a44ad5ba14b0297c8bbdfa3ee4e4f
Autor:
Mafalda Ribeiro, Aya Elghajiji, Scott P. Fraser, Zoë D. Burke, David Tosh, Mustafa B. A. Djamgoz, Paulo R. F. Rocha
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Breast cancer is one of the most prevalent types of cancers worldwide and yet, its pathophysiology is poorly understood. Single-cell electrophysiological studies have provided evidence that membrane depolarization is implicated in the proliferation a
Externí odkaz:
https://doaj.org/article/44aada60764e4dd1ab1f66ef1045542e
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Host immunity recognizes and eliminates most early tumor cells, yet immunological checkpoints, exemplified by CTLA-4, PD-1, and PD-L1, pose a significant obstacle to effective antitumor immune responses. T-lymphocyte co-inhibitory pathways influence
Externí odkaz:
https://doaj.org/article/94e648e4fb2f4e5ba568220973d58cf8
Publikováno v:
Clinical & Experimental Metastasis. 39:679-689
A plethora of ion channels have been shown to be involved systemically in the pathophysiology of cancer and ion channel blockers can produce anti-metastatic effects. However, although ion channels are known to frequently function in concerted action,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55b933af2f68142473641eab61272ea
https://doi.org/10.1007/s10585-022-10166-7
https://doi.org/10.1007/s10585-022-10166-7
Autor:
Mustafa B A, Djamgoz
Publikováno v:
Reviews of physiology, biochemistry and pharmacology. 183
Ion transporting proteins (ITPs) comprise a wide range of ion channels, exchangers, pumps and ionotropic receptors many of which are expressed in tumours and contribute dynamically to the different components and stages of the complex cancer process,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52fcd2254d6f63b67ef272c90301c2c8
https://pubmed.ncbi.nlm.nih.gov/35018530
https://pubmed.ncbi.nlm.nih.gov/35018530
Autor:
Peter Quicke, Yilin Sun, Mar Arias-Garcia, Corey D. Acker, Mustafa B. A. Djamgoz, Chris Bakal, Amanda J. Foust
Cancer cells feature a resting membrane potential (Vm) that is depolarized compared to normal cells, and express active ionic conductances, which factor directly in their pathophysiological behavior. Despite similarities to ‘excitable’ tissues, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a73b7b498693b9e32456636ab8a4522f
https://doi.org/10.1101/2021.12.20.473148
https://doi.org/10.1101/2021.12.20.473148
Autor:
Peter Quicke, Yilin Sun, Mar Arias-Garcia, Melina Beykou, Corey D. Acker, Mustafa B. A. Djamgoz, Chris Bakal, Amanda J. Foust
Publikováno v:
Communications biology. 5(1)
Cancer cells feature a resting membrane potential (Vm) that is depolarized compared to normal cells, and express active ionic conductances, which factor directly in their pathophysiological behavior. Despite similarities to ‘excitable’ tissues, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830712dd5bd699fa52efe17c1584d4fb
https://pubmed.ncbi.nlm.nih.gov/36369329
https://pubmed.ncbi.nlm.nih.gov/36369329
Publikováno v:
Clinicalexperimental metastasis. 39(4)
A plethora of ion channels have been shown to be involved systemically in the pathophysiology of cancer and ion channel blockers can produce anti-metastatic effects. However, although ion channels are known to frequently function in concerted action,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::590759d1746b3836a5f99308646f7654
https://pubmed.ncbi.nlm.nih.gov/35643818
https://pubmed.ncbi.nlm.nih.gov/35643818
Publikováno v:
Bioelectricity
Background: A “neonatal” splice-form of the voltage-gated sodium channel Nav1.5 is functionally expressed in human cancers and potentiates metastatic cell behaviors. Splicing causes the replacement of 7 amino acids, including a negatively charged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec9ac39c30e8d194f980db2e9294ce91
https://pubmed.ncbi.nlm.nih.gov/34471817
https://pubmed.ncbi.nlm.nih.gov/34471817
Publikováno v:
British journal of pharmacologyREFERENCES. 179(3)
Voltage-gated sodium (NaCells expressing either nNaSeveral clinically used blockers of NaWe conclude that the cancer-related nNa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::259f8fb37a0a7c3bfdfdbf736c7adad2
https://pubmed.ncbi.nlm.nih.gov/34411279
https://pubmed.ncbi.nlm.nih.gov/34411279