Zobrazeno 1 - 10 of 128 pro vyhledávání: '"Mustafa Kocak"'
1
Akademický článek
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition
Autor: Noha A. M. Shendy, Melissa Bikowitz, Logan H. Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M. Delahunty, Sarah Robinson, Vanshita Goel, Matthew G. Rees, Melissa A. Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A. Roth, Yingzhe Wang, Burgess B. Freeman, Brent A. Orr, Brian J. Abraham, Martine F. Roussel, Ernst Schonbrunn, Jun Qi, Adam D. Durbin
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Chemical discovery efforts commonly target individual protein domains. Many proteins, including the EP300/CBP histone acetyltransferases (HATs), contain several targetable domains. EP300/CBP are critical gene-regulatory targets in cancer, wi
Externí odkaz: https://doaj.org/article/398968e4bfb8412fb2122ae3a754c4c5
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2
Akademický článek
Acromegaly coexisting with turner syndrome
Autor: Savas Volkan Kisioglu, Yasemin Emur Gunay, Murat Hakkı Yarar, Mustafa Kocak
Publikováno v: Endocrine and Metabolic Science, Vol 3, Iss , Pp 100086- (2021)
Introduction: Acromegaly is a clinical syndrome associated with overexpression of the growth hormone (GH). Turner syndrome (TS) is a rare chromosomal disorder resulting from partial or complete loss of X chromosome and is a common chromosome anomaly
Externí odkaz: https://doaj.org/article/bfe6e25a0bc04195b9e65e634a588174
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3
Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists
Autor: Douglas L, Orsi, Elisabeth, Pook, Nico, Bräuer, Anders, Friberg, Philip, Lienau, Christopher T, Lemke, Timo, Stellfeld, Ulf, Brüggemeier, Vera, Pütter, Hanna, Meyer, Maria, Baco, Stephanie, Tang, Andrew D, Cherniack, Lindsay, Westlake, Samantha A, Bender, Mustafa, Kocak, Craig A, Strathdee, Matthew, Meyerson, Knut, Eis, Jonathan T, Goldstein
Publikováno v: Journal of medicinal chemistry. 65(21)
The ligand-activated nuclear receptor peroxisome-proliferator-activated receptor-γ (PPARG or PPARγ) represents a potential target for a new generation of cancer therapeutics, especially in muscle-invasive luminal bladder cancer where PPARγ is a cr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae813451ab4026cd308dc1142c4ed2b6
https://pubmed.ncbi.nlm.nih.gov/36542814
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Plný text Recenzováno Digitální knihovna AV ČR
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