Tracking aCAD-ALK gene rearrangement in urine and blood of a colorectal cancer patient treated with an ALK inhibitor

Autor: Siravegna, G. ^†, Sartore-Bianchi, A. ^†, Mussolin, B. ^†, Cassingena, A., Amatu, A., Novara, L., Buscarino, M., Corti, G., Crisafulli, G., Bartolini, A., Tosi, F., Erlander, M., Di Nicolantonio, F., Siena, S. ^#, Bardelli, A. ^{*, #}

Publikováno v: In Annals of Oncology June 2017 28(6):1302-1308

Multicenter evaluation of circulating cell-free DNA extraction and downstream analyses for the development of standardized (Pre)analytical work flows

Autor: Lampignano, R. Neumann, M.H.D. Weber, S. Kloten, V. Herdean, A. Voss, T. Groelz, D. Babayan, A. Tibbesma, M. Schlumpberger, M. Chemi, F. Rothwell, D.G. Wikman, H. Galizzi, J.-P. Bergheim, I.R. Russnes, H. Mussolin, B. Bonin, S. Voigt, C. Musa, H. Pinzani, P. Lianidou, E. Brady, G. Speicher, M.R. Pantel, K. Betsou, F. Schuuring, E. Kubista, M. Ammerlaan, W. Sprenger-Haussels, M. Schlange, T. Heitzer, E.

BACKGROUND: In cancer patients, circulating cell-free DNA (ccfDNA) can contain tumor-derived DNA (ctDNA), which enables noninvasive diagnosis, real-time monitoring, and treatment susceptibility testing. However, ctDNA fractions are highly variable, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::ad927c2b7379b9e9c0811136b7795f31
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077470

Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance.

Autor: Amodio V; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Lamba S; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Chilà R; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy., Cattaneo CM; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy., Mussolin B; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Corti G; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Rospo G; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Berrino E; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy; Department of Medical Sciences, University of Torino, Torino, Italy., Tripodo C; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, 90127 Palermo, Italy., Pisati F; Histopathology Unit, Cogentech S.C.a.R.L., 20139, Milan, Italy., Bartolini A; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Aquilano MC; Department of Hematology, Oncology, and Molecular Medicine, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy., Marsoni S; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy., Mauri G; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, 20162 Milan, Italy., Marchiò C; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy; Department of Medical Sciences, University of Torino, Torino, Italy., Abrignani S; Istituto Nazionale Genetica Molecolare INGM 'Romeo ed Enrica Invernizzi', 20122 Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy., Di Nicolantonio F; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy., Germano G; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy. Electronic address: giovanni.germano@unito.it., Bardelli A; Department of Oncology, University of Torino, 10060 Candiolo, TO, Italy; Candiolo Cancer Institute, FPO - IRCCS, 10060 Candiolo, TO, Italy. Electronic address: alberto.bardelli@unito.it.

Publikováno v: Cancer cell [Cancer Cell] 2023 Jan 09; Vol. 41 (1), pp. 196-209.e5. Date of Electronic Publication: 2022 Dec 29.

Memory CD8 ⁺ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination.

Autor: Brasu N; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Department of Oncology, University of Turin, Turin, Italy., Elia I; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Russo V; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Department of Oncology, University of Turin, Turin, Italy., Montacchiesi G; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Department of Oncology, University of Turin, Turin, Italy., Stabile SA; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., De Intinis C; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Fesi F; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Gizzi K; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Macagno M; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Montone M; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Mussolin B; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Grifoni A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA., Faravelli S; Armenise-Harvard Lab. of Structural Biology Dept. Biology and Biotechnology, University of Pavia, Pavia, Italy., Marchese S; Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy., Forneris F; Armenise-Harvard Lab. of Structural Biology Dept. Biology and Biotechnology, University of Pavia, Pavia, Italy., De Francesco R; Istituto Nazionale Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy.; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA.; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA, USA., Barnaba V; Pasteur Institute Italy-Fondazione Cenci Bolognetti, Rome, Italy.; Departement Scienze Cliniche, Interistiche, Anestesiologiche e Cardiovascolari, Sapienza University, Rome, Italy., Sottile A; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy., Sapino A; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy.; Department of Medical Sciences, University of Turin, Turin, Italy., Pace L; G. Armenise-Harvard Immune Regulation Unit, IIGM, Candiolo, TO, Italy. luigia.pace@iigm.it.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, TO, Italy. luigia.pace@iigm.it.

Publikováno v: Nature immunology [Nat Immunol] 2022 Oct; Vol. 23 (10), pp. 1445-1456. Date of Electronic Publication: 2022 Sep 22.

Temozolomide drives mismatch repair deficiency and fosters neoantigen generation in tumor cells

Autor: Amodio, V, Grmano, G, Barault, L, Lamba, S, Rospo, G, Magri, A, Maione, F, Crisafulli, G, Cancelliere, C, Lerda, G, Bartolini, A, Siravegna, G, Mussolin, B, Frappolli, R, Montone, M, Randon, G, de Braud, F, Angelozzi, Na, Marsoni, S, D'Incalci, M, Orlandi, A, Giraudo, E, Satore-Bianchi, A, Siena, S, Pietrantonio, F, Di Nicolantonio, F, Bardelli, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______970::db33f568681ce3329c4adb84dfcd50fb
http://hdl.handle.net/2318/1762737