Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mussie Ghezu Hadera"'
Autor:
Nils-Anders Labba, Hallvard Austin Wæhler, Nora Houdaifi, Denis Zosen, Fred Haugen, Ragnhild Elisabeth Paulsen, Mussie Ghezu Hadera, Ragnhild Eskeland
Publikováno v:
Toxicology and applied pharmacology. 449
Epidemiological studies have linked long-term/high-dose usage of paracetamol (N-acetyl-para-aminophenol, APAP) during pregnancy to adverse neuropsychiatric outcomes, primarily attention-deficit hyperactive disorder (ADHD), in the offspring. Though va
Autor:
Marthe Fredheim Fjelldal, Ana Šulović, Ragnhild E. Paulsen, Mussie Ghezu Hadera, Lars Peter Engeset Austdal, Jannike Mørch Andersen, Mette Kongstorp
Publikováno v:
International Journal of Developmental Neuroscience. 78:19-27
The use of opioids during pregnancy has been associated with neurodevelopmental toxicity in exposed children, leading to cognitive and behavioural deficits later in life. The N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B plays critical roles i
Autor:
Ragnhild E. Paulsen, Steven Verhaegen, Evelien Verbruggen, Marie Kerhoas, Erik Ropstad, Eva Henriette Willemijn Huiberts, Karin Elisabeth Zimmer, Hanne Friis Berntsen, Mussie Ghezu Hadera, Ajay Yadav
Publikováno v:
Reproductive Toxicology
Primary cultures of cerebellar granule neurons (CGNs) derived from chicken embryos were used to explore the effects on developmental neurotoxicity by a complex defined mixture of persistent organic pollutants (POPs). Its chemical composition and conc
Autor:
Hanne Friis Berntsen, Steven Verhaegen, Oddvar Myhre, Mussie Ghezu Hadera, Line Småstuen Haug, Karin Elisabeth Zimmer, Jan Ludvig Lyche, Ragnhild E. Paulsen, Vidar Berg, Ajay Yadav, Azemira Sabaredzovic, Fernando Boix, Erik Ropstad
Publikováno v:
Neurotoxicology
Persistent organic pollutants (POPs) can reach the fetal brain and contribute to developmental neurotoxicity. To explore the distribution of POPs to the fetal brain, we exposed chicken embryos to a POP mixture, containing 29 different compounds with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb65e3b62bcbf711dd793146923c619
https://hdl.handle.net/11250/3009307
https://hdl.handle.net/11250/3009307
Autor:
Mussie Ghezu Hadera, D. V. Zosen, Ragnhild E. Paulsen, Jannike Mørch Andersen, Josephine Sena Lumor
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 112:107105
Introduction Rodent models are routinely used to assess the safety and developmental toxicity of pharmaceuticals, along with analysis of their distribution. These models require sacrifice of parent females, have challenges in the estimation of the nu
Autor:
Lars Evje, Marcel Leist, Simon Gutbier, Paula M. Alves, Ana P. Teixeira, Mussie Ghezu Hadera, Catarina Brito, Ursula Sonnewald, Enrico Glaab, Margit Henry, Susanne Kleiderman, João V. Sá, Agapios Sachinidis
Publikováno v:
Glia. 64:695-715
Availability of homogeneous astrocyte populations would facilitate research concerning cell plasticity (metabolic and transcriptional adaptations; innate immune responses) and cell cycle reactivation. Current protocols to prepare astrocyte cultures d
Autor:
Ursula Sonnewald, Jan Albrecht, Magdalena Zielińska, Katarzyna Dąbrowska, Mussie Ghezu Hadera
Publikováno v:
Journal of Neurochemistry. 136:329-338
Glutamine (Gln) is synthesized in astrocytes from glutamate (Glu) and ammonia, whereupon it can be released to be transferred to neurons. This study evaluated the as yet not definitely established role of the astrocytic Gln transporters SN1 and SN2 (
Autor:
Olav B. Smeland, Haytham Eloqayli, Tore Wergeland Meisingset, Saied A. Jaradat, Karin Borges, Mussie Ghezu Hadera, Ursula Sonnewald, Tanya S. McDonald
Publikováno v:
Neurochemical Research. 41:86-95
Epilepsy is a severe neurological disorder characterized by altered electrical activity in the brain. Important pathophysiological mechanisms include disturbed metabolism and homeostasis of major excitatory and inhibitory neurotransmitters, glutamate
Publikováno v:
Journal of Neuroscience Research. 93:1157-1164
Pentylenetetrazol, kainic acid, or pilocarpine can be used to induce seizures in animal models of epilepsy. The present Review describes disturbances in astrocyte-neuron interactions in the acute, latent, and chronic phases analyzed by magnetic reson
Publikováno v:
IBRO Reports. 6:S465