Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Musleeha Chesor"'
Autor:
Jack Tuffin, Musleeha Chesor, Valeryia Kuzmuk, Tim Johnson, Simon C. Satchell, Gavin I. Welsh, Moin A. Saleem
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Tuffin et al. demonstrate a method for culturing conditionally immortalized human podocytes and GEnCs in 3D by forming spheroid cultures termed GlomSpheres, which are found to segregate in an organized manner. These are shown to establish a GBM-like
Externí odkaz:
https://doaj.org/article/3454bab16428421b8cab931ece01a44c
Autor:
Carl J. May, Musleeha Chesor, Sarah E. Hunter, Bryony Hayes, Rachel Barr, Tim Roberts, Fern A. Barrington, Louise Farmer, Lan Ni, Maisie Jackson, Heidi Snethen, Nadia Tavakolidakhrabadi, Max Goldstone, Rodney Gilbert, Matt Beesley, Rachel Lennon, Rebecca Foster, Richard Coward, Gavin I. Welsh, Moin A. Saleem
Publikováno v:
Kidney International.
Autor:
Gavin I. Welsh, Musleeha Chesor, Mario Barac-Nieto, Issam M. Francis, Slava Malatiali, Moin A. Saleem
Publikováno v:
Journal of Diabetes Mellitus. 10:27-40
Glomerular tuft immune reactive Ezrin surface area (EzA) and fraction of EzA to total glomerular tuft area significantly increased, indicating podocyte growth, rounding and altered cytoskeletal interactions at 1 week of STZ diabetes. Podocyte number
Autor:
Musleeha Chesor, Jack Tuffin, Carl May, Irene Ghobrial, Melissa Little, Gavin Welsh, Moin Saleem
Recurrence of steroid-resistant nephrotic syndrome (SRNS) is thought to be due to an unknown “circulating factor”, the identity of which has so far remained elusive. Our previous work suggests a signaling role for protease-activated receptor-1 (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec5cbf9af712e73c86c9a71a2b74f9b
https://doi.org/10.21203/rs.3.rs-1226619/v1
https://doi.org/10.21203/rs.3.rs-1226619/v1
Autor:
Musleeha Chesor, Gavin I. Welsh, Valeryia Kuzmuk, Tim Johnson, Jack Tuffin, Simon C. Satchell, Moin A. Saleem
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Tuffin, J, Chesor, M, Kuzmuk, V, Johnson, T, Satchell, S C, Welsh, G I & Saleem, M 2021, ' GlomSpheres as a 3D co-culture spheroid model of the kidney glomerulus for rapid drug-screening ', Communications Biology, vol. 4, no. 1, 1351 . https://doi.org/10.1038/s42003-021-02868-7
Communications Biology
Tuffin, J, Chesor, M, Kuzmuk, V, Johnson, T, Satchell, S C, Welsh, G I & Saleem, M 2021, ' GlomSpheres as a 3D co-culture spheroid model of the kidney glomerulus for rapid drug-screening ', Communications Biology, vol. 4, no. 1, 1351 . https://doi.org/10.1038/s42003-021-02868-7
The glomerulus is the filtration unit of the kidney. Injury to any component of this specialised structure leads to impaired filtration and eventually fibrosis and chronic kidney disease. Current two and three dimensional (2D and 3D) models that atte
Autor:
Kamphon Intharanut, Pussadee Tobunluepop, Phatchira Thattanon, Musleeha Chesor, Oytip Nathalang, Supattra Mitundee, Siriporn Nathalang
Publikováno v:
Indian Journal of Hematology and Blood Transfusion. 34:506-509
Diego (DI) blood group genotyping is clinically important in Asian populations. Data of Diego blood type among southern Thais is still unknown. This study aimed to report DI*A and DI*B allele frequencies in southern Thai blood donors and to estimate
Autor:
Gavin I. Welsh, Richard W J Lee, Musleeha Chesor, Carl May, Moin A. Saleem, Phillipa J. Lait, Lauren P Schewitz-Bowers
Publikováno v:
Am J Physiol Renal Physiol
May, C J, Welsh, G I, Chesor, M, Lait, P J, Schewitz-Bowers, L P, Lee, R W J & Saleem, M A 2019, ' Human Th17 cells produce a soluble mediator that increases podocyte motility via signaling pathways that mimic PAR-1 activation ', American Journal of Physiology-Renal Physiology, vol. 317, no. 4, pp. F913-F921 . https://doi.org/10.1152/ajprenal.00093.2019
May, C J, Welsh, G I, Chesor, M, Lait, P J, Schewitz-Bowers, L P, Lee, R W J & Saleem, M A 2019, ' Human Th17 cells produce a soluble mediator that increases podocyte motility via signaling pathways that mimic PAR-1 activation ', American Journal of Physiology-Renal Physiology, vol. 317, no. 4, pp. F913-F921 . https://doi.org/10.1152/ajprenal.00093.2019
The specific pathogenesis of idiopathic nephrotic syndrome (NS) is poorly understood, and the role of immune mediators remains contentious. However, there is good evidence for the role of a circulating factor, and we recently postulated circulating p
Publikováno v:
Oncology Reports. 31:1754-1760
The Wilms' tumor 1 (WT1) gene encodes a zinc finger which appears to be a transcriptional activator or repressor for many genes involved in cell differentiation, growth and apoptosis. In order to determine the relationship between WT1 and related pro