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A plant-produced H1N1 trimeric hemagglutinin protects mice from a lethal influenza virus challenge

Autor: Shoji, Y., Jones, R.M., Mett, V., Chichester, J.A., Musiychuk, K., Sun, X.J., Tumpey, T.M., Green, B.J., Shamloul, M., Norikane, J., Bi, H., Hartman, C.E., Bottone, C., Stewart, M., Streatfield, S.J., Yusibov, V.

The increased worldwide awareness of seasonal and pandemic influenza, including pandemic H1N1 virus, has stimulated interest in the development of economic platforms for rapid, large-scale production of safe and effective subunit vaccines. In recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::cd0c1efef0991b6930b154d6904bf393
https://publica.fraunhofer.de/handle/publica/232281

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A plant-produced protective antigen vaccine confers protection in rabbits against a lethal aerosolized challenge with Bacillus anthracis Ames spores

Autor: Chichester, J.A., Manceva, S.D., Rhee, A., Coffin, M.V., Musiychuk, K., Mett, V., Shamloul, M., Norikane, J., Streatfield, S.J., Yusibov, V.

The potential use of Bacillus anthracis as a bioterrorism weapon threatens the security of populations globally, requiring the immediate availability of safe, efficient and easily delivered anthrax vaccine for mass vaccination. Extensive research eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::322a15bdfc9c848a7585351d902b84d9
https://publica.fraunhofer.de/handle/publica/232282

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A plant-based system for rapid production of influenza vaccine antigens

Autor: Shoji, Y., Farrance, C.E., Bautista, J., Bi, H., Musiychuk, K., Horsey, A., Park, H., Jaje, J., Green, B.J., Shamloul, M., Sharma, S., Chichester, J.A., Mett, V., Yusibov, V.

Please cite this paper as: Shoji et al. (2011) A plant-based system for rapid production of influenza vaccine antigens. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2011.00295.x. Background: Influenza virus is a globally important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::8d52db962ab63ea4ad7b6a0553535289
https://publica.fraunhofer.de/handle/publica/228015

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Production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expressing bacterial PNGase F

Autor: Mamedov, T., Ghosh, A., Jones, R.M., Mett, V., Farrance, C.E., Musiychuk, K., Horsey, A., Yusibov, V.

Application of tools of molecular biology and genomics is increasingly leading towards the development of recombinant protein-based biologics. As such, it is leading to an increased diversity of targets that have important health applications and req

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::50407110ec8f74d3dce8f7553f01e40d
https://publica.fraunhofer.de/handle/publica/228982

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A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge

Autor: Mett, V., Chichester, J.A., Stewart, M.L., Musiychuk, K., Bi, H., Reifsnyder, C.J., Hull, A.K., Albrecht, M.T., Goldman, S., Baillie, L.W.J., Yusibov, V.

The health and economic burden of infectious diseases in general and bioterrorism in particular necessitate the development of medical countermeasures. One proven approach to reduce the disease burden and spread of pathogen is treatment with monoclon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::b46df5bc9899f4ea966ddc911e1b24d4
https://publica.fraunhofer.de/handle/publica/224953

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