Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Musheng, Xu"'
Autor:
Rabal, Obdulia, Sánchez-Arias, Juan A., Cuadrado-Tejedor, Mar, de Miguel, Irene, Pérez-González, Marta, García-Barroso, Carolina, Ugarte, Ana, Estella-Hermoso de Mendoza, Ander, Sáez, Elena, Espelosin, Maria, Ursua, Susana, Haizhong, Tan, Wei, Wu, Musheng, Xu, Garcia-Osta, Ana, Oyarzabal, Julen
Publikováno v:
In European Journal of Medicinal Chemistry 25 April 2018 150:506-524
Autor:
Robert A. Craig, Brian M. Fox, Cheng Hu, Katrina W. Lexa, Maksim Osipov, Arun P. Thottumkara, Martin Larhammar, Takashi Miyamoto, Anil Rana, Lesley A. Kane, Ernie Yulyaningsih, Hilda Solanoy, Hoang Nguyen, Roni Chau, Timothy Earr, Yuji Kajiwara, Daniel Fleck, Anthony Lucas, Patrick C. G. Haddick, Ryan H. Takahashi, Vincent Tong, Jing Wang, Mark J. Canet, Suresh B. Poda, Kimberly Scearce-Levie, Ankita Srivastava, Zachary K. Sweeney, Musheng Xu, Rui Zhang, Jianrong He, Yanan Lei, Zheng Zhuo, Javier de Vicente
Publikováno v:
Journal of Medicinal Chemistry. 65:16290-16312
Dual leucine zipper kinase (DLK) and leucine zipper-bearing kinase (LZK) are regulators of neuronal degeneration and axon growth. Therefore, there is a considerable interest in developing DLK/LZK inhibitors for neurodegenerative diseases. Herein, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba59c66263d4a021ad8e4342b49383cd
https://doi.org/10.1021/acs.jmedchem.2c01056
https://doi.org/10.1021/acs.jmedchem.2c01056
Publikováno v:
Environmental Science and Pollution Research. 30:4642-4652
Adsorption technology can effectively remove phosphorus from water and realize phosphorus recovery. Hence, it is used to curb the eutrophication of water and alleviate the crisis caused by the shortage of phosphorus resources. Resin has been attracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0841c10f4c6854d8282f847e744c480
https://doi.org/10.1007/s11356-022-22525-8
https://doi.org/10.1007/s11356-022-22525-8
Autor:
Elena Sáez, Musheng Xu, Raquel Ordoñez, Amaia Vilas-Zornoza, Feifei Zhang, Xabier Agirre, Antonio Pineda-Lucena, Obdulia Rabal, Julen Oyarzabal, Felipe Prosper, Edurne San José-Enériz, Estíbaliz Miranda, Irene de Miguel, Leire Garate, Juan A. Sánchez-Arias, Ander Estella, Wei Wu
Publikováno v:
Journal of Medicinal Chemistry. 64:3392-3426
Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8ef28e03f4b1381fbbbd762da2c60a
https://doi.org/10.1021/acs.jmedchem.0c02255
https://doi.org/10.1021/acs.jmedchem.0c02255
Autor:
Obdulia, Rabal, Edurne, San José-Enériz, Xabier, Agirre, Juan Antonio, Sánchez-Arias, Irene, de Miguel, Raquel, Ordoñez, Leire, Garate, Estíbaliz, Miranda, Elena, Sáez, Amaia, Vilas-Zornoza, Antonio, Pineda-Lucena, Ander, Estella, Feifei, Zhang, Wei, Wu, Musheng, Xu, Felipe, Prosper, Julen, Oyarzabal
Publikováno v:
Journal of medicinal chemistry. 64(6)
Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bad3640d9d5cb27668dc78f6b1e780a3
https://pubmed.ncbi.nlm.nih.gov/33661013
https://pubmed.ncbi.nlm.nih.gov/33661013
Publikováno v:
Elementa: Science of the Anthropocene. 9
Widespread overuse and misuse of antibiotics has led to unintended consequences, and it is necessary to find effective ways to remove antibiotics. In this study, a visible-light-response photocatalyst zinc ferrite (ZnFe2O4) was synthesized via a hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ee668f2b068e294bf4d92b3c0c9bb7
https://doi.org/10.1525/elementa.2020.00096
https://doi.org/10.1525/elementa.2020.00096
Autor:
Luke Whitesell, Luke Steere, Musheng Xu, Brittany H. Frederick, Sang Hu Kim, C. Tony Liu, Chunliang Liu, Yong-Kang Zhang, Cari McGregor, Haibo Zhou, Leah E. Cowen, Yasheen Zhou, Timothy Pastoor, Yan Cai, Jiangong Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 43:128089
Several boron-containing small molecules have been approved by the US FDA to treat human diseases. We explored potential applications of boron-containing compounds in modern agriculture by pursuing multiple research and development programs. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b333be7917b378479b6afd23df453adb
https://doi.org/10.1016/j.bmcl.2021.128089
https://doi.org/10.1016/j.bmcl.2021.128089
Autor:
Yingying Liu, Edurne San José-Enériz, Leire Garate, Jose A. Martinez-Climent, Raúl F. Pérez, Elena Sáez, Pablo Santamarina, Xabier Agirre, María José García-Barchino, Estíbaliz Miranda, Sergio Roa, Raquel Ordoñez, Amaia Vilas-Zornoza, Irene de Miguel, Juan A. Sánchez-Arias, Ana Ugarte, Musheng Xu, Mario F. Fraga, Obdulia Rabal, Julen Oyarzabal, Felipe Prosper, Wei Wu
Publikováno v:
Journal of medicinal chemistry. 61(15)
Using knowledge- and structure-based approaches, we designed and synthesized reversible chemical probes that simultaneously inhibit the activity of two epigenetic targets, histone 3 lysine 9 methyltransferase (G9a) and DNA methyltransferases (DNMT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18800942df446096b03a6a0ee2178016
https://pubmed.ncbi.nlm.nih.gov/29953809
https://pubmed.ncbi.nlm.nih.gov/29953809
Autor:
Edurne San José-Enériz, Leire Garate, Estíbaliz Miranda, Wei Wu, Xabier Agirre, Irene de Miguel, Jose A. Martinez-Climent, Yingying Liu, Juan A. Sánchez-Arias, Elena Sáez, Musheng Xu, Julen Oyarzabal, Obdulia Rabal, Felipe Prosper, Sergio Roa
Publikováno v:
Journal of medicinal chemistry. 61(15)
Epigenetic regulators that exhibit aberrant enzymatic activities or expression profiles are potential therapeutic targets for cancers. Specifically, enzymes responsible for methylation at histone-3 lysine-9 (like G9a) and aberrant DNA hypermethylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309f3af0971c525df6830e693ec4eb8a
https://pubmed.ncbi.nlm.nih.gov/29890830
https://pubmed.ncbi.nlm.nih.gov/29890830
Autor:
W-H Chang, T. Lu, L. Wang, C-H Chen, Thomas W. Weickert, Cs-J Fann, H-G Hwu, Cynthia Shannon Weickert, D Liu, Dai Zhang, Sarah Y. Mccoy, Y Shen, C-M Liu, Stephen V. Faraone, Yishan Shi, Y-L Liu, Weihua Yue, Xu-Feng Huang, Debora A. Rothmond, C-C Wen, Stephen J. Glatt, Danielle Weinberg, Ori S. Cohen, Musheng Xu, Tetsufumi Kanazawa, Wei Tang, Lin He, Ronglin Che, Cherrie Galletly, J Yan, T M Duncan, C-C Chang, Ming T. Tsuang, Jay L. Hess, L M Paish, Frank A. Middleton, Q Xu
Publikováno v:
Molecular Psychiatry. 21:975-982
The rs1076560 polymorphism of DRD2 (encoding dopamine receptor D2) is associated with alternative splicing and cognitive functioning; however, a mechanistic relationship to schizophrenia has not been shown. Here, we demonstrate that rs1076560(T) impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c8f2be3e1803af3f9f2f26542db07c
https://doi.org/10.1038/mp.2015.137
https://doi.org/10.1038/mp.2015.137