Výsledky vyhledávání - "Musemma K. Muhammed"

CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice

Autor: Torben Sølbeck Rasmussen, Anna Kirstine Koefoed, Ling Deng, Musemma K. Muhammed, Geneviève M. Rousseau, Witold Kot, Sabrina Sprotte, Horst Neve, Charles M.A.P. Franz, Axel Kornerup Hansen, Finn Kvist Vogensen, Sylvain Moineau, Dennis Sandris Nielsen

Publikováno v: Rasmussen, T S, Koefoed, A K, Deng, L, Muhammed, M K, Rousseau, G M, Kot, W, Sprotte, S, Neve, H, Franz, C M A P, Hansen, A K, Vogensen, F K, Moineau, S & Nielsen, D S 2023, ' CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice ', ISME Journal, vol. 17, pp. 432–442 . https://doi.org/10.1038/s41396-023-01358-4

Many prokaryotes harbor the adaptive CRISPR-Cas system, which stores small nucleotide fragments from previous invasions of nucleic acids via viruses or plasmids. This molecular archive blocks further invaders carrying identical or similar nucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936a5e4f180242def03930f516330093
https://curis.ku.dk/portal/da/publications/crisprcas-provides-limited-phage-immunity-to-a-prevalent-gut-bacterium-in-gnotobiotic-mice(44314f1b-810e-4360-80ea-c46333aef11c).html

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Akademický článek

A high-throughput qPCR system for simultaneous quantitative detection of dairy Lactococcus lactis and Leuconostoc bacteriophages.

Autor: Musemma K Muhammed, Lukasz Krych, Dennis S Nielsen, Finn K Vogensen

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174223 (2017)

Simultaneous quantitative detection of Lactococcus (Lc.) lactis and Leuconostoc species bacteriophages (phages) has not been reported in dairies using undefined mixed-strain DL-starters, probably due to the lack of applicable methods. We optimized a

Externí odkaz: https://doaj.org/article/fbdd7dcc3b164235be762660f970a6a9

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Correlates of Gut Function in Children Hospitalized for Severe Acute Malnutrition, a Cross-sectional Study in Uganda

Autor: Dennis Sandris Nielsen, Maria Wiese, Nicolette N Barungi, Pingping Jiang, Hanne Frøkiær, Benedikte Grenov, Betty Lanyero, Christian Mølgaard, Maren Jh Rytter, Henrik Friis, Ezekiel Mupere, Kim F. Michaelsen, Musemma K. Muhammed, Hanifa Namusoke, Hannah Pesu, Vibeke Brix Christensen

Publikováno v: Journal of Pediatric Gastroenterology & Nutrition. 69:292-298

Children with severe acute malnutrition (SAM) may have impaired intestinal function, which can result in malabsorption, diarrhoea, and poor growth. This study evaluated the gut function of children with SAM using fecal and blood biomarkers and assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5afb78e591330afa61e03a18989a690
https://doi.org/10.1097/mpg.0000000000002381

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Efficient chemical hydrophobization of lactic acid bacteria – One-step formation of double emulsion

Autor: Musemma K. Muhammed, Kathryn A. Whitehead, Jens Risbo, Elhamalsadat Shekarforoush, Nils Arneborg, Adam Cohen Simonsen, Xiaoyi Jiang

Publikováno v: Jiang, X, Shekarforoush, E, Muhammed, M K, Whitehead, K, Simonsen, A C, Arneborg, N & Risbo, J 2021, ' Efficient chemical hydrophobization of lactic acid bacteria – One-step formation of double emulsion ', Food Research International, vol. 147, 110460 . https://doi.org/10.1016/j.foodres.2021.110460

A novel concept of stabilizing multiple-phase food structure such as emulsion using solely the constitutional bacteria enables an all-natural food grade formulation and thus a clean label declaration. In this paper, we propose an efficient approach t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92b6119db51cf083903fa546aff630f
https://curis.ku.dk/ws/files/333631138/oa_LC_modification_symplectic.pdf

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Investigation of the bacteriophage community in induced lysates of undefined mesophilic mixed-strain DL-cultures using classical and metagenomic approaches

Autor: Søren J. Sørensen, Musemma K. Muhammed, Witold Kot, Horst Neve, Mette L. Olsen, Knut J. Heller, Dennis Sandris Nielsen, Thomas Janzen, Lars Hestbjerg Hansen, Finn K. Vogensen, Josué L. Castro-Mejía

Publikováno v: Muhammed, M K, Olsen, M L, Kot, W, Neve, H, Castro-Mejia, J L, Janzen, T, Hansen, L H, Nielsen, D S, Sorensen, S J, Heller, K J & Vogensen, F K 2018, ' Investigation of the bacteriophage community in induced lysates of undefined mesophilic mixed-strain DL-cultures using classical and metagenomic approaches ', International Journal of Food Microbiology, vol. 272, pp. 61-72 . https://doi.org/10.1016/j.ijfoodmicro.2018.02.012

To investigate the notion that starter cultures can be a reservoir of bacteriophages (phages) in the dairy environment, strains of three DL-starters (undefined mesophilic mixed-strain starters containing Lactococcus lactis subsp. lactis biovar. diace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0869e82a6a8c2d45c5789d7716ebfa25
https://doi.org/10.1016/j.ijfoodmicro.2018.02.012

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Metagenomic Analysis of Dairy Bacteriophages: Extraction Method and Pilot Study on Whey Samples Derived from Using Undefined and Defined Mesophilic Starter Cultures

Autor: Knut J. Heller, Finn K. Vogensen, Horst Neve, Dennis Sandris Nielsen, Josué L. Castro-Mejía, Douwe van Sinderen, Lukasz Krych, Witold Kot, Musemma K. Muhammed, Søren J. Sørensen, Jennifer Mahony, Lars Hestbjerg Hansen

Publikováno v: Muhammed, M K, Kot, W, Neve, H, Mahony, J, Castro-Mejia, J L, Krych, L, Hansen, L H, Nielsen, D S, Sorensen, S J, Heller, K J, van Sinderen, D & Vogensen, F K 2017, ' Metagenomic Analysis of Dairy Bacteriophages : Extraction Method and Pilot Study on Whey Samples Derived from Using Undefined and Defined Mesophilic Starter Cultures ', Applied and Environmental Microbiology, vol. 83, no. 19, e00888-17 . https://doi.org/10.1128/AEM.00888-17

Despite being potentially highly useful for characterizing the biodiversity of phages, metagenomic studies are currently not available for dairy bacteriophages, partly due to the lack of a standard procedure for phage extraction. We optimized an extr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927fe345ef612ba68aa6ba02fa8bc651
https://pubmed.ncbi.nlm.nih.gov/28754704

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A high-throughput qPCR system for simultaneous quantitative detection of dairy Lactococcus lactis and Leuconostoc bacteriophages

Autor: Lukasz Krych, Dennis Sandris Nielsen, Finn K. Vogensen, Musemma K. Muhammed

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174223 (2017)
PLoS ONE
Muhammed, M K, Krych, L, Nielsen, D S & Vogensen, F K 2017, ' A high-throughput qPCR system for simultaneous quantitative detection of dairy Lactococcus lactis and Leuconostoc bacteriophages ', PLOS ONE, vol. 12, no. 3, e0174223 . https://doi.org/10.1371/journal.pone.0174223

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02b0dd0a5c1852ee95de012be8dd477
http://europepmc.org/articles/PMC5365131?pdf=render

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New Insights into Staphylococcus aureus Stress Tolerance and Virulence Regulation from an Analysis of the Role of the ClpP Protease in the Strains Newman, COL, and SA564

Autor: Antti Sukura, Kerttu Koskenniemi, Julie H. Andersen, Kirsi Savijoki, Dereje Dadi Gudeta, Dorte Frees, Lene Hemmingsen, Pekka Varmanen, Tuula A. Nyman, Musemma K. Muhammed, Kristoffer T. Bæk

Publikováno v: Journal of Proteome Research. 11:95-108

In Staphylococcus aureus, ClpP proteases were previously shown to be essential for virulence and stress tolerance in strains derived from NCTC8325. Because these strains exhibit a severely reduced activity of the alternative sigma factor, SigB, we he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f48c0a0552dc6576ecbd75fd8964810
https://doi.org/10.1021/pr200956s

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Optimizing protocols for extraction of bacteriophages prior to metagenomic analyses of phage communities in the human gut

Autor: Charles M. A. P. Franz, Horst Neve, Lars Hestbjerg Hansen, Josué L. Castro-Mejía, Witold Kot, Dennis Sandris Nielsen, Musemma K. Muhammed, Finn K. Vogensen

Publikováno v: Castro Mejia, J L, Muhammed, M K, Kot, W P, Neve, H, Franz, C M A P, Hansen, L H, Vogensen, F K & Nielsen, D S 2015, ' Optimizing protocols for extraction of bacteriophages prior to metagenomic analyses of phage communities in the human gut ', Microbiome, vol. 3, 64 . https://doi.org/10.1186/s40168-015-0131-4
Microbiome

Background The human gut is densely populated with archaea, eukaryotes, bacteria, and their viruses, such as bacteriophages. Advances in high-throughput sequencing (HTS) as well as bioinformatics have opened new opportunities for characterizing the v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac16aeae28647247b485e6e37a1ab13
https://curis.ku.dk/ws/files/153042214/Castro_Mejia_2015_Optimizing_protocols_for_extraction.pdf

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