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Putative Receptors for Gravity Sensing in Mammalian Cells: The Effects of Microgravity

Autor: Michele Aventaggiato, Federica Barreca, Enza Vernucci, Mariano Bizzarri, Elisabetta Ferretti, Matteo A. Russo, Marco Tafani

Publikováno v: Applied Sciences, Vol 10, Iss 6, p 2028 (2020)

Gravity is a constitutive force that influences life on Earth. It is sensed and translated into biochemical stimuli through the so called “mechanosensors”, proteins able to change their molecular conformation in order to amplify external cues cau

Externí odkaz: https://doaj.org/article/b19757235c4249aeb9dfbb10c7bb54f1

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Putative Receptors for Gravity Sensing in Mammalian Cells: The Effects of Microgravity

Autor: Mariano Bizzarri, Enza Vernucci, Elisabetta Ferretti, Marco Tafani, Michele Aventaggiato, Matteo Antonio Russo, Federica Barreca

Publikováno v: Applied Sciences, Vol 10, Iss 6, p 2028 (2020)

Gravity is a constitutive force that influences life on Earth. It is sensed and translated into biochemical stimuli through the so called “mechanosensors”, proteins able to change their molecular conformation in order to amplify external cues cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3ca2f0ac0b38d7db67fcd15eef51c2
https://www.mdpi.com/2076-3417/10/6/2028

SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation

Autor: Shuang Zhao, Xuesong Li, Chan Chen, Jin Liu, Guoliang Meng, Zhe Lin, Yuanqing Gao, Lihong Pan, Meng-Lin Chao, Albert Ferro, Hong Jiang, Yi Han, Hongshan Chen, Xin Wang, Qiulun Lu, Hong Wang, Liping Xie, Xin Tang, Chun Wang, Yong Ji, Zhengrong Huang, Feiyue Dai

Publikováno v: Tang, X, Pan, L, Zhao, S, Dai, F, Chao, M, Jiang, H, Li, X, Lin, Z, Huang, Z, Meng, G, Wang, C, Chen, C, Liu, J, Wang, X, Ferro, A, Wang, H, Chen, H, Gao, Y, Lu, Q, Xie, L, Han, Y & Ji, Y 2020, ' SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation ', Circulation, vol. 141, no. 12, pp. 984-1000 . https://doi.org/10.1161/CIRCULATIONAHA.119.042336

Background: S-nitrosylation (SNO), a prototypic redox-based posttranslational modification, is involved in the pathogenesis of cardiovascular disease. The aim of this study was to determine the role of SNO of MLP (muscle LIM protein) in myocardial hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6c335fbdb8f66d387542506d6138f7
https://kclpure.kcl.ac.uk/ws/files/122069349/S_Nitrosylation_of_Muscle_TANG_Accepted18December2019_Published06January2020_AAM.pdf