Výsledky vyhledávání - "Muscle, Skeletal/cytology"

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

Autor: Nora Yucel, Glenn J. Markov, Peder J. Lund, Michael Angelo, Helen M. Blau, Yu Xin Wang, Ermelinda Porpiglia, Sean C. Bendall, Thach Mai, Benjamin A. Garcia

Publikováno v: Cell Reports, Vol 27, Iss 13, Pp 3939-3955.e6 (2019)
Yucel, N, Wang, Y X, Mai, T, Porpiglia, E, Lund, P J, Markov, G, Garcia, B A, Bendall, S C, Angelo, M & Blau, H M 2019, ' Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function ', Cell Reports, vol. 27, no. 13, pp. 3939-3955.e6 . https://doi.org/10.1016/j.celrep.2019.05.092
Cell reports

SUMMARY The impact of glucose metabolism on muscle regeneration remains unresolved. We identify glucose metabolism as a crucial driver of histone acetylation and myogenic cell fate. We use single-cell mass cytometry (CyTOF) and flow cytometry to char

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d904754dceaf42c26af3f27554043794
http://www.sciencedirect.com/science/article/pii/S2211124719307314

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The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses

Autor: Duan, Jingxian, Navarro-Dorado, Jorge, Clark, Jill H., Kinnear, Nicholas P., Meinke, Peter, Schirmer, Eric C., Evans, A. Mark

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Duan, J, Navarro-Dorado, J, Clark, J H, Kinnear, N P, Meinke, P, Schirmer, E C & Evans, A M 2019, ' The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses ', vol. 10, no. 1, 2299 . https://doi.org/10.1038/s41467-019-10055-w

Ca2+ coordinates diverse cellular processes, yet how function-specific signals arise is enigmatic. We describe a cell-wide network of distinct cytoplasmic nanocourses with the nucleus at its centre, demarcated by sarcoplasmic reticulum (SR) junctions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffc11d47fb4f5fa382f7478ce0c96696
https://doaj.org/article/1588c52787ed490bbdbdcbdbcc560603

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Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection

Autor: Lieselot Decroix, Pieter Annaert, Dacha Gholobova, Nico Callewaert, Lieven Thorrez, Melanie Gérard, Linda Desender

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports

The development of laboratory-grown tissues, referred to as organoids, bio-artificial tissue or tissue-engineered constructs, is clearly expanding. We describe for the first time how engineered human muscles can be applied as a pre- or non-clinical m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446606df3c41b060ebf7e9e9add381dd
http://link.springer.com/article/10.1038/s41598-018-30123-3

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Mechanoreciprocity in cell migration

Autor: Peter Friedl, Sjoerd van Helvert, Cornelis Storm

Publikováno v: Nature Cell Biology, 20(1), 8-20. Nature Publishing Group
Nature Cell Biology, 20, 1, pp. 8-20
Nature Cell Biology, 20, 8-20

Item does not contain fulltext Cell migration is an adaptive process that depends on and responds to physical and molecular triggers. Moving cells sense and respond to tissue mechanics and induce transient or permanent tissue modifications, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674204663ddb22d304f0e08eca0f0556
http://www.scopus.com/inward/record.url?scp=85042134690&partnerID=8YFLogxK

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Effects of Dietary Protein and Fat Content on Intrahepatocellular and Intramyocellular Lipids during a 6-Day Hypercaloric, High Sucrose Diet: A Randomized Controlled Trial in Normal Weight Healthy Subjects

Autor: Jérémy Cros, Virgile Lecoultre, Bertrand Pouymayou, Anna Surowska, Chris Boesch, Léonie Egli, Robin Rosset, Anne-Sophie Marques, Roland Kreis, Vanessa Campos, Luc Tappy, Philippe Schneiter, P. Jegatheesan

Publikováno v: Nutrients
Volume 11
Issue 1
Nutrients, vol. 11, no. 1
Surowska, Anna; Jegatheesan, Prasanthi; Campos, Vanessa; Marques, Anne-Sophie; Egli, Léonie; Cros, Jérémy; Rosset, Robin; Lecoultre, Virgile; Kreis, Roland; Boesch, Christoph Hans; Pouymayou, Bertrand Michel Marie; Kreis, Roland; Tappy, Luc (2019). Effects of Dietary Protein and Fat Content on Intrahepatocellular and Intramyocellular Lipids during a 6-Day Hypercaloric, High Sucrose Diet: A Randomized Controlled Trial in Normal Weight Healthy Subjects. Nutrients, 11(1) Molecular Diversity Preservation International MDPI 10.3390/nu11010209
Nutrients, Vol 11, Iss 1, p 209 (2019)

Sucrose overfeeding increases intrahepatocellular (IHCL) and intramyocellular (IMCL) lipid concentrations in healthy subjects. We hypothesized that these effects would be modulated by diet protein/fat content. Twelve healthy men and women were studie

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Congenital eyelid ptosis, decreased glomerular filtration, and orthostatic hypotension

Autor: Tessa Wassenberg, Michèl Willemsen, Henry Dijkman, Jaap Deinum, Leo Monnens

Publikováno v: Pediatric Nephrology, 32, 1171-1174
Pediatric Nephrology (Berlin, Germany)
Pediatric Nephrology, 32, 7, pp. 1171-1174

Contains fulltext : 174487.pdf (Publisher’s version ) (Open Access) 01 juli 2017

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb14810271cba70a15d2c1b10ec192c
https://biblio.vub.ac.be/vubir/(743361ad-ffe2-48fb-bd25-64ce6cfa449f).html

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Congenital eyelid ptosis, decreased glomerular filtration, and orthostatic hypotension: Questions

Autor: Leo A. H. Monnens, Tessa Wassenberg, Jaap Deinum, Henry B.P.M. Dijkman, Michèl A.A.P. Willemsen

Publikováno v: Pediatric Nephrology, 32, 1169-1170
Pediatric Nephrology, 32, 7, pp. 1169-1170
Pediatric Nephrology (Berlin, Germany)

Contains fulltext : 174488.pdf (Publisher’s version ) (Open Access) 01 juli 2017

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9601e8856624e1de8982341c08ad7063
https://doi.org/10.1007/s00467-016-3494-2

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Cellular and molecular investigations into the development of the pectoral girdle

Autor: April DeLaurier, Yaniv Hinits, Helen Sang, Petr Valasek, Darrell J. R. Evans, Gavin Brooks, Bodo Christ, Susanne Theis, James E.N. Minchin, Ruijin Huang, Graham Luke, Anthony Otto, Liwen He, Malcolm Logan, Ketan Patel

Publikováno v: Valasek, P, Theis, S, DeLaurier, A, Hinits, Y, Luke, G N, Otto, A M, Minchin, J, He, L W, Christ, B, Brooks, G, Sang, H, Evans, D J, Logan, M, Huang, R J & Patel, K 2011, ' Cellular and molecular investigations into the development of the pectoral girdle ', Developmental Biology, vol. 357, no. 1, pp. 108-116 . https://doi.org/10.1016/j.ydbio.2011.06.031

The forelimbs of higher vertebrates are composed of two portions: the appendicular region (stylopod, zeugopod and autopod) and the less prominent proximal girdle elements (scapula and clavicle) that brace the limb to the main trunk axis. We show that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c51eaf325a50cbb5bfa6ffd6f8b754
https://doi.org/10.1016/j.ydbio.2011.06.031

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