Zobrazeno 1 - 10
of 3 878
pro vyhledávání: '"Muscarinic acetylcholine receptor M3"'
Autor:
Beatrix Pfanzagl, Erika Jensen-Jarolim
Publikováno v:
Endocrine and Metabolic Science, Vol 15, Iss , Pp 100167- (2024)
The interaction of nutrients and bacterial-derived products and their enteroendocrine effects are still enigmatic. We used the human enteroendocrine tumour cell line P-STS isolated from the terminal ileum as cellular sentinel. In this model, P-STS ce
Externí odkaz:
https://doaj.org/article/3287a8d56c494fd296fcd2cbc891c102
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7560 (2024)
The muscarinic acetylcholine receptor M3 (M3-mAChR) is involved in various physiological and pathological processes. Owing to specific cardioprotective effects, M3-mAChR is an ideal diagnostic and therapeutic biomarker for cardiovascular diseases (CV
Externí odkaz:
https://doaj.org/article/e50e459c361640babf1a96bff31a2f80
Autor:
Tuoheti YAKUFU·, Kainan ZHANG, Hui ZHAO, Dawuti WUBULITALIFU·, Rui ZHANG, Renyong LIN, Guodong LYU
Publikováno v:
Zhongguo quanke yixue, Vol 25, Iss 17, Pp 2110-2114 (2022)
Background Alpha-fetoprotein (AFP) is a common diagnostic marker for hepatocellular carcinoma (HCC) , a highly malignant cancer, but its sensitivity is only 41%-65%, and the rate of missed diagnosis is relatively high. Therefore, there is an urgent n
Externí odkaz:
https://doaj.org/article/17e835e961bd4596b6698c63f0d0476e
Akademický článek
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Autor:
Leonard A. Lobbes, Marcel A. Schütze, Raoul Droeser, Marco Arndt, Ioannis Pozios, Johannes C. Lauscher, Nina A. Hering, Benjamin Weixler
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8198 (2023)
Muscarinic acetylcholine receptor M3 (M3R) has repeatedly been shown to be prominently expressed in human colorectal cancer (CRC), playing roles in proliferation and cell invasion. Its therapeutic targetability has been suggested in vitro and in anim
Externí odkaz:
https://doaj.org/article/2634da35d73d467f97caa6dd48c77442
Akademický článek
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Autor:
Chang-Hao Zhong, Di-Fei Chen, Yu-Long Luo, Ming-Yue Fan, Shiyue Li, Chun-Li Tang, Xiao-Bo Chen, Zhu-Quan Su, Yu Chen, Zi-Qing Zhou, Yanqiuzi Cheng
Publikováno v:
Allergology International, Vol 71, Iss 1, Pp 66-72 (2022)
Background The effects of bronchial thermoplasty (BT) on smooth muscle (SM) and nerves in small airways are unclear. Methods We recruited 15 patients with severe refractory asthma, who received BT treatment. Endobronchial optical-coherence tomography
Akademický článek
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Publikováno v:
Open Access Macedonian Journal of Medical Sciences. 9:890-899
AIM: This study aims to investigate the concentration of cyclic adenosine monophosphate (cAMP), inositol 1,4,5-trisphosphate (IP3), calcium (Ca2+), and the expression phosphorylated myosin light chain (MLC) in Rattus norvegicus scleral fibroblast cel
Autor:
Shunichi Kajioka, Takao Ishigami, Kazuyuki Sakamoto, Akiyoshi Someya, Masahiro Takeda, Hideyoshi Fuji, Kenichiro Ishizu, Naoki Yoshimura, Hajime Takamatsu, Hironori Yuyama, Risa Okimoto, Noriyuki Masuda, Katsutoshi Ino, Akiyoshi Ohtake
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:64-73
Muscarinic M3 (M3) receptors mediate a wide range of acetylcholine (ACh)-induced functions, including visceral smooth-muscle contraction and glandular secretion. Positive allosteric modulators (PAMs) can avoid various side effects of muscarinic agoni