Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Musashi Kubiura-Ichimaru"'
Autor:
Takamasa Ito, Musashi Kubiura-Ichimaru, Yuri Murakami, Aaron B. Bogutz, Louis Lefebvre, Isao Suetake, Shoji Tajima, Masako Tada
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of opposing enzymatic activities: DNA methyltransferases (DNMTs) and Ten-eleven translocation dioxygenases
Externí odkaz:
https://doaj.org/article/99641d88b0f941718b248c99fdd478dc
Autor:
Ken Higashimoto, Feifei Sun, Eri Imagawa, Ken Saida, Noriko Miyake, Satoshi Hara, Hitomi Yatsuki, Musashi Kubiura-Ichimaru, Atsushi Fujita, Takeshi Mizuguchi, Naomichi Matsumoto, Hidenobu Soejima
Publikováno v:
Journal of Medical Genetics; Jun2024, Vol. 61 Issue 6, p590-5, 12p
Autor:
Masako Tada, Takamasa Ito, Musashi Kubiura-Ichimaru, Fumihito Miura, Shinpei Yamaguchi, Shoji Tajima, M. Azim Surani, Takashi Ito
DNA methyltransferases and TET enzymes dynamically regulate the DNA methylation-demethylation cycles during mouse embryonic development. DNMT1 maintains cell-specific DNA methylation after DNA replication. However, little is known about the physiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12cadf3deb5cb2fe9aa2ec0ee8e3d8c
https://doi.org/10.21203/rs.3.rs-2788282/v1
https://doi.org/10.21203/rs.3.rs-2788282/v1
Autor:
Musashi Kubiura-Ichimaru, Christopher Penfold, Kazuaki Kojima, Constance Dollet, Haruka Yabukami, Katsunori Semi, Yasuhiro Takashima, Thorsten Boroviak, Hideya Kawaji, Knut Woltjen, Aki Minoda, Erika Sasaki, Toshiaki Watanabe
SummaryPrimate germ cell development remains largely unexplored due to limitations in sample collection and the long duration of development. In mice, primordial germ cell-like cells (PGCLCs) derived from pluripotent stem cells (PSCs) can develop int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d811b9f4bff310e4f03c64bb985b9111
https://doi.org/10.1101/2022.09.20.508677
https://doi.org/10.1101/2022.09.20.508677
Autor:
Keiko Ooeda1, Musashi Kubiura-Ichimaru1, Saori Tsuji2, Shota Okuyama1, Mao Yamashita1, Akari Mine1, Fumihiko Kawamura1, Takafumi Ueyama2, Masako Tada1 masako.tada@sci.toho-u.ac.jp
Publikováno v:
Pharmacology Research & Perspectives. Oct2020, Vol. 8 Issue 5, p1-12. 12p.
Autor:
Hiroshi Kimura, Mitsuo Oshimura, Yumi Asano, Miho Yoshii, Masako Tada, Ayaka Hayashi, Yoichi Matsuda, Takamasa Ito, Musashi Kubiura-Ichimaru
Publikováno v:
Genes & Genomics
Background DNA methylation is a significant epigenetic modification that is evolutionarily conserved in various species and often serves as a repressive mark for transcription. DNA methylation levels and patterns are regulated by a balance of opposin
Publikováno v:
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 29(2)
DNA methylation is an essential epigenetic mark that regulates normal mammalian embryonic development. DNA methylation profiles are not always static, especially during germline development. In zygotes, DNA is typically highly methylated but, during
Autor:
Takafumi Ueyama, Keiko Ooeda, Mao Yamashita, Musashi Kubiura-Ichimaru, Shota Okuyama, Masako Tada, Fumihiko Kawamura, Akari Mine, Saori Tsuji
Publikováno v:
Pharmacology Research & Perspectives
Cytochrome P450 enzymes (CYP) function in drug metabolism in the liver. To evaluate numerous drug candidates, a high‐content screening (HCS) system with hepatocyte‐like cells (HLCs) that can replace adult human hepatocytes is required. Human hepa