Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Murugesan Sasikumar"'
Autor:
Duraivelu, Hemanand, Dhamodharan, Udaya Suriya Rajkumar, Udayaraju, Pamula, Prakash, S. Jaya, Murugesan, Sasikumar
Publikováno v:
Journal of Information Technology Management (JITM); 2024, Vol. 16 Issue 1, p135-148, 14p
Publikováno v:
New Journal of Chemistry. 43:15052-15056
Novel dendrimer supported spiroborate catalysts 2 and 3 have been synthesized using a click reaction as a key step. The catalytic efficiency of the catalysts have been verified with reduction of (E)-O-benzyl oxime 13 as a model substrate. Catalyst 3
Autor:
Shirish P. Deshmukh, Mohammad Mujahid, Murugan Muthukrishnan, Murugesan Sasikumar, Prashant Mujumdar
Publikováno v:
Tetrahedron: Asymmetry. 28:983-986
A simple and efficient synthesis of the opioid analgesic agent ( R )-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.
Autor:
Murugesan Sasikumar, Murugan Muthukrishnan, Sunita S. Kunte, Jambu Subramanian, Viswanadh Nalla, Mohammad Mujahid
Publikováno v:
New Journal of Chemistry. 41:824-829
A concise and efficient enantioselective synthesis of both enantiomers of bepridil, a calcium channel blocker, is reported. Jacobsen's hydrolytic kinetic resolution method was utilized to resolve racemic 2-(isobutoxymethyl)oxirane. The incorporation
Autor:
Savio, Max1, Murugesan, Sasikumar2
Publikováno v:
International Journal on Electrical Engineering & Informatics. Mar2014, Vol. 6 Issue 1, p129-143. 15p.
Publikováno v:
Tetrahedron Letters. 57:861-863
An alternate synthesis of (R)-2-benzylmorpholine 1, an appetite suppressant agent has been accomplished starting from readily available trans-cinnamyl alcohol employing Sharpless asymmetric epoxidation strategy as a key step, with an overall yield of
Publikováno v:
Synthesis. 46:1751-1756
An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, suc
Autor:
Mohammad Mujahid, Sunita S. Kunte, Prashant Mujumdar, Murugan Muthukrishnan, Murugesan Sasikumar
Publikováno v:
Tetrahedron: Asymmetry. 23:1512-1515
A simple and efficient synthesis of levetiracetam has been achieved with high enantiopurity (>99%) starting from commercially available benzyl glycidyl ether. The method is amenable for industrial scale-up.
Autor:
Murugesan Sasikumar, Milind D. Nikalje
Publikováno v:
Synthetic Communications. 42:3061-3067
A refinement in the synthetic strategy for (S)-dapoxetine 1 is described. The key features of synthetic strategy include (a) a Sharpless asymmetric epoxidation reaction and regioselective reductive ring opening of a 2,3-epoxy alcohol to elaborate the
Publikováno v:
Tetrahedron: Asymmetry. 22:1353-1357
An efficient asymmetric synthesis of the new antiepileptic drug, Lacosamide is described in high enantiopurity (>98% ee), using Jacobsen’s hydrolytic kinetic resolution strategy as a key step.