Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Murugaiah, A M Subbaiah"'
Publikováno v:
Green Chemistry. 25:2368-2377
We report a metal catalyst-free, HF-free and open-flask green protocol for the electrophilic hydrazination of enoxy silanes at an energy-efficient room temperature, taking advantage of the eco-safe EtOH–H2O solvent.
Publikováno v:
The Journal of Organic Chemistry. 87:14778-14792
Synthetically important α-oxoketene aminal intermediates can now be accessed from readily available and inexpensive carbodiimides as starting materials via the nucleophilic addition of palladium enolates derived from enol silane precursors. This ope
Publikováno v:
The Journal of Organic Chemistry.
Publikováno v:
The Journal of organic chemistry. 87(21)
The scope of an umpolung approach to expand synthetic access to bifunctional γ-keto hydrazine intermediates
Publikováno v:
Journal of Medicinal Chemistry. 64:14046-14128
The benzene moiety is the most prevalent ring system in marketed drugs, underscoring its historic popularity in drug design either as a pharmacophore or as a scaffold that projects pharmacophoric elements. However, introspective analyses of medicinal
Publikováno v:
The Journal of Organic Chemistry. 86:14356-14370
In contrast to the conventional 1,4-addition process, regioselective 1,2-addition of silyl enol ethers to quinones can now be achieved via a palladium(II) enolate pathway that provides access to 4-hydroxy-4-(2-oxo-2-arylethyl)cyclohexa-2,5-dien-1-one
Autor:
Murugaiah, A M Subbaiah, Lakshumanan, Subramani, Thangeswaran, Ramar, Salil, Desai, Sarmistha, Sinha, Sandhya, Mandlekar, John F, Kadow, Susan, Jenkins, Mark, Krystal, Murali, Subramanian, Srikanth, Sridhar, Shweta, Padmanabhan, Priyadeep, Bhutani, Rambabu, Arla, Nicholas A, Meanwell
Publikováno v:
Journal of medicinal chemistry. 65(16)
Structure-property relationships associated with a series of (carbonyl)oxyalkyl amino acid ester prodrugs of the marketed HIV-1 protease inhibitor atazanavir (
Autor:
Siddheshwar Kisan Chauthe, Anuradha Gupta, Muralidhararao Bagadi, Lakshumanan Subramani, Murugesan Shyamsundar, Lakshmikant Bajpai, Arvind Mathur, Murugaiah A. M. Subbaiah
Publikováno v:
SEPARATION SCIENCE PLUS. 4:16-23
Publikováno v:
The Journal of organic chemistry. 87(7)
The scope of chemoselective β-hydride elimination in the context of arylation/alkenylation of homoenolates from cyclopropanol precursors using organoboronic reagents as transmetalation coupling partners was examined. The reaction optimization paradi
Publikováno v:
The Journal of organic chemistry. 85(12)
Organoborane reagents were investigated as coupling partners to cyclopropanol-derived β-ketone enolates in the presence of a chelated Pd(II) catalyst. Efficient coupling of a range of electronically and sterically diverse cyclopropanols and aryl/alk