Výsledky vyhledávání - "Murty Vundavalli V"

Akademický článek

Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha

Autor: Pothuri Bhavana, Wright Jason D, Kaufmann Andreas M, Subramaniyam Shivakumar, Nandula Subhadra V, Narayan Gopeshwar, Scotto Luigi, Mansukhani Mahesh, Schneider Achim, Arias-Pulido Hugo, Murty Vundavalli V

Publikováno v: Molecular Cancer, Vol 7, Iss 1, p 58 (2008)

Abstract Background Copy number gains and amplifications are characteristic feature of cervical cancer (CC) genomes for which the underlying mechanisms are unclear. These changes may possess oncogenic properties by deregulating tumor-related genes. G

Externí odkaz: https://doaj.org/article/46225dd79f0941d2b43eb9255d0b731d

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Akademický článek

Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression

Autor: Mansukhani Mahesh, Dürst Matthias, Schneider Achim, Kaufmann Andreas M, Arias-Pulido Hugo, Goparaju Chandra, Narayan Gopeshwar, Pothuri Bhavana, Murty Vundavalli V

Publikováno v: Molecular Cancer, Vol 5, Iss 1, p 16 (2006)

Abstract Background Cervical Cancer (CC) exhibits highly complex genomic alterations. These include hemizygous deletions at 4p15.3, 10q24, 5q35, 3p12.3, and 11q24, the chromosomal sites of Slit-Robo pathway genes. However, no candidate tumor suppress

Externí odkaz: https://doaj.org/article/530b51807cef426eb9e2b9b6470cc1b9

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Akademický článek

Frequent Promoter Methylation of CDH1, DAPK, RARB, and HIC1 Genes in Carcinoma of Cervix Uteri: Its Relationship to Clinical Outcome

Autor: Schneider Achim, Villella Jeannine, Zhang Fang F, Vargas Hernan, Koul Sanjay, Arias-Pulido Hugo, Narayan Gopeshwar, Terry Mary B, Mansukhani Mahesh, Murty Vundavalli V

Publikováno v: Molecular Cancer, Vol 2, Iss 1, p 24 (2003)

Abstract Background Cervical cancer (CC), a leading cause of cancer-related deaths in women worldwide, has been causally linked to genital human papillomavirus (HPV) infection. Although a host of genetic alterations have been identified, molecular ba

Externí odkaz: https://doaj.org/article/5dba1273efa04856a7301d036748d8b3

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Akademický článek

Characteristic promoter hypermethylation signatures in male germ cell tumors

Autor: Bosl George J, Reuter Victor E, McKiernan James M, Donadio Alessia, Mansukhani Mahesh M, Houldsworth Jane, Koul Sanjay, Chaganti Raju S, Murty Vundavalli V

Publikováno v: Molecular Cancer, Vol 1, Iss 1, p 8 (2002)

Abstract Background Human male germ cell tumors (GCTs) arise from undifferentiated primordial germ cells (PGCs), a stage in which extensive methylation reprogramming occurs. GCTs exhibit pluripotentality and are highly sensitive to cisplatin therapy.

Externí odkaz: https://doaj.org/article/e0f89dea9b704fbbbab45fb515b9667c

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