Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway.

Autor: Murtaza, Munazza¹, Khan, Gulnaz¹, Aftab, Meha Fatima¹, Afridi, Shabbir Khan¹, Ghaffar, Safina¹, Ahmed, Ayaz¹, Hafizur, Rahman M.¹, Waraich, Rizwana Sanaullah¹ rizwanas.waraich@gmail.com

Publikováno v: PLoS ONE. 6/9/2017, Vol. 12 Issue 6, p1-13. 13p.

A new glycotoxins inhibitor attenuates insulin resistance in liver and fat cells

Autor: Afridi, Shabbir Khan, Aftab, Meha Fatima, Murtaza, Munazza, Ghaffar, Safina, Karim, Aneela, Mughal, Uzma Rasool, Khan, Khalid Mohammed, Waraich, Rizwana Sanaullah

Publikováno v: In Biochemical and Biophysical Research Communications 5 August 2016 476(4):188-195

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A bis-Schiff base of isatin improves methylglyoxal mediated insulin resistance in skeletal muscle cells.

Autor: Aftab MF; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Afridi SK; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Ghaffar S; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Murtaza M; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Khan M; HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Karim A; HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Khan KM; HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Waraich RS; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan. rizwanas.waraich@gmail.com.

Publikováno v: Archives of pharmacal research [Arch Pharm Res] 2015 Oct 30, pp. . Date of Electronic Publication: 2015 Oct 30.