Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Murtada Shubbar"'
Autor:
Siming Chen, Murtada Shubbar, Zhe Chen, Xin Yang, Xin Liu, Josep Rizo, Qiong Wu, Lianying Jiao, Qi Zhang
Publikováno v:
Proc Natl Acad Sci U S A
Enhancer of Zeste Homolog 2 (EZH2) is the catalytic subunit of Polycomb Repressive Complex 2 (PRC2), which minimally requires two other subunits, EED and SUZ12, for enzymatic activity. EZH2 has been traditionally known to mediate histone H3K27 trimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c63cd3024830290941a198b91ada412
https://europepmc.org/articles/PMC7382310/
https://europepmc.org/articles/PMC7382310/
Autor:
Murtada Shubbar, Ilona Christy Unarta, Xuhui Huang, Xin Liu, Lizhe Zhu, Matthew A. Bratkowski
Publikováno v:
Journal of Biological Chemistry. 293:1651-1665
Functional cross-talk between the promoter and terminator of a gene has long been noted. Promoters and terminators are juxtaposed to form gene loops in several organisms, and gene looping is thought to be involved in transcriptional regulation. The g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0912247d362bbe2d03deec469d7a4b
https://doi.org/10.1074/jbc.m117.811521
https://doi.org/10.1074/jbc.m117.811521
Summary Developmentally regulated accessory subunits dictate PRC2 function. Here, we report the crystal structures of a 120 kDa heterotetrameric complex consisting of Suz12, Rbbp4, Jarid2, and Aebp2 fragments that is minimally active in nucleosome bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31e11c64070263c76b1cec6bc6673fa
https://europepmc.org/articles/PMC5912153/
https://europepmc.org/articles/PMC5912153/