Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mursal Nader"'
Autor:
Jiawei Wang, Mursal Nader, Can Cui, Martina Damo, Achia Khatun, Ivana William, Julie F. Cheung, Nikhil S. Joshi, Eric Fagerberg, Smita Krishnaswamy, Amanda Hutchins, Gena G. Foster, Weiguo Cui, Isabel Monroy, Moujtaba Y. Kasmani, Aarthi Venkat, Brittany Fitzgerald, Hongyu Zhao, Manik Kuchroo, Kelli A. Connolly, Noah I. Hornick, Dylan L. Mariuzza
Publikováno v:
Science Immunology. 6
Tumor-specific CD8 + T cells in stable tumor-draining lymph node reservoir are clonally and developmentally related to those in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41f715a2520f1cb44ad2833c27cb0906
https://doi.org/10.1126/sciimmunol.abg7836
https://doi.org/10.1126/sciimmunol.abg7836
Autor:
Kelli A, Connolly, Manik, Kuchroo, Aarthi, Venkat, Achia, Khatun, Jiawei, Wang, Ivana, William, Noah I, Hornick, Brittany L, Fitzgerald, Martina, Damo, Moujtaba Y, Kasmani, Can, Cui, Eric, Fagerberg, Isabel, Monroy, Amanda, Hutchins, Julie F, Cheung, Gena G, Foster, Dylan L, Mariuzza, Mursal, Nader, Hongyu, Zhao, Weiguo, Cui, Smita, Krishnaswamy, Nikhil S, Joshi
Publikováno v:
Sci Immunol
“Stem-like” TCF1(+) CD8(+) T cells (T(SL)) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e6e92f53c1eaaa1f1c6306e7c6ecb7b
https://pubmed.ncbi.nlm.nih.gov/34597124
https://pubmed.ncbi.nlm.nih.gov/34597124
Autor:
Elliot H. Akama-Garren, Da-Yae Lee, Vasilena Gocheva, Leah Marie Schmidt, Brittany Fitzgerald, Alice Boileve, Can Cui, Nikhil S. Joshi, Julie Cheung, Martina Damo, Gena G. Foster, Isabel Monroy, Peter Cabeceiras, Yisi Lu, Prashanth Gokare, Josephine H. Wilson, Kelli A. Connolly, Tyler Jacks, Mursal Nader, Ivana William, Greg P. Chang
Mouse models with inducible neoantigens have been historically difficult to generate because of leaky expression of antigens in the thymus, which causes central tolerance in developing CD8 and CD4 T cells. Attempts to resolve this problem using exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8a12dd9cc0c0c518a51a2d27e37af0
https://doi.org/10.1101/2020.01.09.900894
https://doi.org/10.1101/2020.01.09.900894
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1845
Genetically engineered mouse models (GEMMs), in which autochthonous tumors develop into advanced-stage disease in the presence of a functional immune system, have contributed significantly to the understanding of most types of cancer. Using a GEMM of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8a2f41155920e53f9d4acd97c145e30
https://pubmed.ncbi.nlm.nih.gov/30141018
https://pubmed.ncbi.nlm.nih.gov/30141018
Publikováno v:
Tertiary Lymphoid Structures ISBN: 9781493987085
Genetically engineered mouse models (GEMMs), in which autochthonous tumors develop into advanced-stage disease in the presence of a functional immune system, have contributed significantly to the understanding of most types of cancer. Using a GEMM of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::825461ddd0216a351339bf5c2415a4a2
https://doi.org/10.1007/978-1-4939-8709-2_15
https://doi.org/10.1007/978-1-4939-8709-2_15
Publikováno v:
Clinical Cancer Research. 24:PR06-PR06
Ectopic lymphoid aggregates (LA) located in the vicinity of solid tumors have been identified in human patients with many types of cancers and have been largely associated with improved outcomes. In particular, LA in patients with non-small cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ae1cfd68e0cc64164155ca7fc6cc28
https://doi.org/10.1158/1557-3265.aacriaslc18-pr06
https://doi.org/10.1158/1557-3265.aacriaslc18-pr06
Autor:
Mursal Nader, Nikhil S. Joshi
Publikováno v:
Cancer Research. 78:LB-353
In many human cancer types (i.e., lung, breast, melanoma), infiltrating immune cells are found in complex, lymph node (LN)-like structures known as the tumor-associated tertiary lymphoid structures (TA-TLSs). TA-TLSs are associated with longer patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fc1190dc8f4258f62d93a68b9fc8522
https://doi.org/10.1158/1538-7445.am2018-lb-353
https://doi.org/10.1158/1538-7445.am2018-lb-353