Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mursal, Nader"'
Autor:
Jiawei Wang, Mursal Nader, Can Cui, Martina Damo, Achia Khatun, Ivana William, Julie F. Cheung, Nikhil S. Joshi, Eric Fagerberg, Smita Krishnaswamy, Amanda Hutchins, Gena G. Foster, Weiguo Cui, Isabel Monroy, Moujtaba Y. Kasmani, Aarthi Venkat, Brittany Fitzgerald, Hongyu Zhao, Manik Kuchroo, Kelli A. Connolly, Noah I. Hornick, Dylan L. Mariuzza
Publikováno v:
Science Immunology. 6
Tumor-specific CD8 + T cells in stable tumor-draining lymph node reservoir are clonally and developmentally related to those in tumors.
Autor:
Kelli A, Connolly, Manik, Kuchroo, Aarthi, Venkat, Achia, Khatun, Jiawei, Wang, Ivana, William, Noah I, Hornick, Brittany L, Fitzgerald, Martina, Damo, Moujtaba Y, Kasmani, Can, Cui, Eric, Fagerberg, Isabel, Monroy, Amanda, Hutchins, Julie F, Cheung, Gena G, Foster, Dylan L, Mariuzza, Mursal, Nader, Hongyu, Zhao, Weiguo, Cui, Smita, Krishnaswamy, Nikhil S, Joshi
Publikováno v:
Sci Immunol
“Stem-like” TCF1(+) CD8(+) T cells (T(SL)) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintai
Autor:
Elliot H. Akama-Garren, Da-Yae Lee, Vasilena Gocheva, Leah Marie Schmidt, Brittany Fitzgerald, Alice Boileve, Can Cui, Nikhil S. Joshi, Julie Cheung, Martina Damo, Gena G. Foster, Isabel Monroy, Peter Cabeceiras, Yisi Lu, Prashanth Gokare, Josephine H. Wilson, Kelli A. Connolly, Tyler Jacks, Mursal Nader, Ivana William, Greg P. Chang
Mouse models with inducible neoantigens have been historically difficult to generate because of leaky expression of antigens in the thymus, which causes central tolerance in developing CD8 and CD4 T cells. Attempts to resolve this problem using exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8a12dd9cc0c0c518a51a2d27e37af0
https://doi.org/10.1101/2020.01.09.900894
https://doi.org/10.1101/2020.01.09.900894
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1845
Genetically engineered mouse models (GEMMs), in which autochthonous tumors develop into advanced-stage disease in the presence of a functional immune system, have contributed significantly to the understanding of most types of cancer. Using a GEMM of
Publikováno v:
Tertiary Lymphoid Structures ISBN: 9781493987085
Genetically engineered mouse models (GEMMs), in which autochthonous tumors develop into advanced-stage disease in the presence of a functional immune system, have contributed significantly to the understanding of most types of cancer. Using a GEMM of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::825461ddd0216a351339bf5c2415a4a2
https://doi.org/10.1007/978-1-4939-8709-2_15
https://doi.org/10.1007/978-1-4939-8709-2_15
Publikováno v:
Clinical Cancer Research. 24:PR06-PR06
Ectopic lymphoid aggregates (LA) located in the vicinity of solid tumors have been identified in human patients with many types of cancers and have been largely associated with improved outcomes. In particular, LA in patients with non-small cell lung
Autor:
Mursal Nader, Nikhil S. Joshi
Publikováno v:
Cancer Research. 78:LB-353
In many human cancer types (i.e., lung, breast, melanoma), infiltrating immune cells are found in complex, lymph node (LN)-like structures known as the tumor-associated tertiary lymphoid structures (TA-TLSs). TA-TLSs are associated with longer patien