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of 20
pro vyhledávání: '"Murry A. Stein"'
Autor:
Murry A. Stein, Joel B. Baseman, Jimmy J. Wewer, Victoria E. Centonze, Jorge Timenetsky, Marianna Cagle, Priscilla M. Ueno, Manickam Krishnan
Publikováno v:
Microbiology. 154:3033-3041
Mycoplasma genitalium (Mg) is a mollicute that causes a range of human urogenital infections. A hallmark of these bacteria is their ability to establish chronic infections that can persist despite completion of appropriate antibiotic therapies and in
Autor:
Murry A. Stein, Joel B. Baseman
Publikováno v:
Clinical Microbiology Newsletter. 28:41-48
Mycoplasma genitalium has the smallest genome of any organism capable of independent growth. Sequence comparisons among completed bacterial genomes indicate that the 580-kb genome of M. genitalium arose by minimization of the 816-kb genome of the hum
Autor:
Daniel V. Zurawski, Murry A. Stein
Publikováno v:
Microbiology. 150:2055-2068
SseA, a keySalmonellavirulence determinant, is a small, basic pI protein encoded within theSalmonellapathogenicity island 2 and serves as a type III secretion system chaperone for SseB and SseD. Both SseA partners are subunits of the surface-localize
Publikováno v:
Molecular Microbiology. 48:549-559
The intracellular pathogen, Salmonella enterica serovar Typhimurium, is able to proliferate in phagocytes, although reactive oxygen and nitrogen intermediates are lethal to most phagocytosed bacteria. To determine whether repair of oxidatively damage
Publikováno v:
Infection and Immunity. 71:2247-2252
Three Mu d J prototrophs demonstrated that intracellular replication is a Salmonella virulence trait (K. Y. Leung and B. B. Finlay, Proc. Natl. Acad. Sci. USA, 88: 11470-11474, 1991). mutS and mutH are disrupted in mutants 3-11 and 12-23, and ssaQ is
Autor:
Daniel V. Zurawski, Murry A. Stein
Publikováno v:
Molecular Microbiology. 47:1341-1351
Summary The Salmonella Pathogenicity Island 2 (SPI2) encodes a type III secretion system (TTSS) shown to be critical for adaptation to the intracellular environment within both phagocytic and epithelial cell types. Within SPI2, the Effector region en
Publikováno v:
Journal of Microbiological Methods. 42:129-138
The study of microbial intracellular pathogenesis has benefited from the application of immunofluorescence microscopy to characterize interactions of the pathogen with host cells. Unfortunately, immunofluorescence microscopy is impractical for screen
Publikováno v:
Molecular Microbiology. 37:1417-1435
Salmonella-induced aggregation of host endosomal compartments into tubules, termed lgp-tubules, requires sifA and ompR. Lgp-tubules result from Salmonella-directed alteration of the endocytic system and typify the unique intracellular locale where Sa
Publikováno v:
Infection and Immunity. 66:1806-1811
Outer membrane porin genes of Salmonella typhimurium , including ompC , ompF , and tppB , are regulated by the products of ompB , a two-component regulatory locus encoding OmpR and EnvZ. S. typhimurium ompR mutants are attenuated in mice, but to date
Publikováno v:
Infection and Immunity. 64:4820-4825
It is presumed, but not proven, that enteropathogenic Escherichia coli (EPEC) causes secretory diarrhea by altering ion transport in enterocytes. In this study we used the whole-cell, current clamp variant of the patch clamp technique to demonstrate