First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of EU-GEI Data

Autor: Ferraro, L, Quattrone, D, La Barbera, D, La Cascia, C, Morgan, C, Kirkbride, JB, Cardno, AG, Sham, P, Tripoli, G, Sideli, L, Seminerio, F, Sartorio, C, Szoke, A, Tarricone, I, Bernardo, M, Rodriguez, V, Stilo, SA, Gayer-Anderson, C, de Haan, L, Velthorst, E, Jongsma, H, Bart, RBP, Richards, A, Arango, C, Menezez, PR, Lasalvia, A, Tosato, S, Tortelli, A, Del Ben, CM, Selten, J-P, Jones, PB, van Os, J, The WP2 EU-GEI Group, Di Forti, M, Vassos, E, Murray, RM

Publikováno v: Schizophrenia bulletin, 49(1), 218-227. Oxford University Press
Schizophrenia Bulletin, 49(1). Oxford University Press
Schizophrenia Bulletin, 49(1), 218-227. Oxford University Press

Cluster studies identified a subgroup of patients with psychosis whose premorbid adjustment deteriorates before the onset, which may reflect variation in genetic influence. However, other studies reported a complex relationship between distinctive pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa3d35b94704f25e96f4f4d4f2a6b68
https://doi.org/10.1093/schbul/sbac100

Early intervention in psychosis during the COVID-19 pandemic: Maudsley recommendations

Autor: Jauhar, S, Lai, S, Bonoldi, I, Salazar de Pablo, G, di Forti, M, Alameda, L, Donocik, J, Iacoponi, E, Spencer, T, Haege, B, McLaughlan, D, Taylor, D, Young, AH, Thornicroft, G, Gaughran, F, MacCabe, JH, Murray, RM, McGuire, P, Fusar-Poli, P

Publikováno v: In European Neuropsychopharmacology June 2021 47:130-135

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Autor: Bigdeli, T. B, Ripke, S, Bacanu, Sa, Lee, S. H, Wray, Nr, Gejman, P. V, Rietschel, M, Cichon, S, St Clair, D, Corvin, A, Kirov, G, Mcquillin, A, Gurling, H, Rujescu, D, Andreassen, O. A, Werge, T, Blackwood, D. H. R, Pato, C. N, Pato, M. T, Malhotra, A. K, O'Donovan, M. C, Kendler, K. S, Fanous, A. H, Neale, Bm, Walters, Jt, Farh, Kh, Holmans, Pa, Lee, P, Bulik Sullivan, B, Collier, Da, Huang, H, Pers, Th, Agartz, I, Agerbo, E, Albus, M, Alexander, M, Amin, F, Begemann, M, Belliveau, Ra, Bene, J, Bergen, Se, Bevilacqua, E, Bigdeli, Tb, Black, Dw, Børglum, Ad, Bruggeman, R, Buccola, Ng, Buckner, Rl, Byerley, W, Cahn, W, Cai, G, Campion, D, Cantor, Rm, Carr, Vj, Carrera, N, Catts, Sv, Chambert, Kd, Chan, Rc, Chen, Ry, Chen, Ey, Cheng, W, Cheung, Ef, Chong, Sa, Cloninger, C, Cohen, D, Cohen, N, Cormican, P, Craddock, N, Crowley, Jj, Curtis, D, Davidson, M, Davis, Kl, Degenhardt, F, Del, Favero, J, Delisi, Le, Demontis, D, Dikeos, D, Dinan, T, Djurovic, S, Donohoe, G, Drapeau, E, Duan, J, Dudbridge, F, Durmishi, N, Eichhammer, P, Eriksson, J, Escott Price, V, Essioux, L, Fanous, Ah, Farrell, Ms, Frank, J, Franke, L, Freedman, R, Freimer, Nb, Friedl, M, Friedman, Ji, Fromer, M, Genovese, G, Georgieva, L, Gershon, Es, Giegling, I, Giusti Rodríguez, P, Godard, S, Goldstein, Ji, Golimbet, V, Gopal, S, Gratten, J, Grove, J, Haan, De, L, Hammer, C, Hamshere, Ml, Hansen, M, Hansen, T, Haroutunian, V, Hartmann, Am, Henskens, Fa, Herms, S, Hirschhorn, Jn, Hoffmann, P, Hofman, A, Hollegaard, Mv, Hougaard, Dm, Ikeda, M, Joa, I, Julìa, A, Kahn, Rs, Kalaydjieva, L, Karachanak Yankova, S, Karjalainen, J, Kavanagh, D, Keller, Mc, Kelly, Bj, Kennedy, Jl, Khrunin, A, Kim, Y, Klovins, J, Knowles, Ja, Konte, B, Kucinskas, V, Kucinskiene, Za, Kuzelova Ptackova, H, Kähler, Ak, Laurent, C, Keong, Jl, Lee, S, Legge, Se, Lerer, B, Li, M, Li, T, Liang, Ky, Lieberman, J, Limborska, S, Loughland, Cm, Lubinski, J, Lönnqvist, J, Macek, M, Magnusson, Pk, Maher, Bs, Maier, W, Mallet, J, Marsal, S, Mattheisen, M, Mattingsdal, M, Mccarley, Rw, Mcdonald, C, Mcintosh, Am, Meier, S, Meijer, Cj, Melegh, B, Melle, I, Mesholam Gately, Ri, Metspalu, A, Michie, Pt, Milani, L, Milanova, V, Mokrab, Y, Morris, Dw, Mors, O, Mortensen, Pb, Murphy, Kc, Murray, Rm, Myin Germeys, I, Müller Myhsok, B, Nelis, M, Nenadic, I, Nertney, Da, Nestadt, G, Nicodemus, Kk, Nikitina Zake, L, Nisenbaum, L, Nordin, A, O'Callaghan, E, O'Dushlaine, C, O'Neill, F, Sy, Oh, Olincy, A, Olsen, L, Jv, Os, Pantelis, C, Papadimitriou, Gn, Papiol, S, Parkhomenko, E, Pato, Mt, Paunio, T, Pejovic Milovancevic, M, Perkins, Do, Pietiläinen, O, Pimm, J, Pocklington, Aj, Powell, J, Price, A, Pulver, Ae, Purcell, Sm, Quested, D, Rasmussen, Hb, Reichenberg, A, Reimers, Ma, Richards, Al, Roffman, Jl, Roussos, P, Ruderfer, Dm, Salomaa, V, Sanders, Ar, Schall, U, Schubert, Cr, Schulze, Tg, Schwab, Sg, Scolnick, Em, Scott, Rj, Seidman, Lj, Shi, J, Sigurdsson, E, Silagadze, T, Silverman, Jm, Sim, K, Slominsky, P, Smoller, Jw, Hc, So, Spencer, Cc, Stahl, Ea, Stefansson, H, Steinberg, S, Stogmann, E, Straub, Re, Strengman, E, Strohmaier, J, Stroup, T, Subramaniam, M, Suvisaari, J, Svrakic, Dm, Szatkiewicz, Jp, Söderman, E, Thirumalai, S, Toncheva, D, Tooney, Pa, Tosato, Sarah, Veijola, J, Waddington, J, Walsh, D, Wang, D, Wang, Q, Webb, Bt, Weiser, M, Wildenauer, Db, Williams, Nm, Williams, S, Witt, Sh, Wolen, Ar, Wong, Eh, Wormley, Bk, Jq, Wu, Hs, Xi, Zai, Cc, Zheng, X, Zimprich, F, Stefansson, K, Visscher, Pm, Adolfsson, R, Andreassen, Oa, Blackwood, Dh, Bramon, E, Buxbaum, Jd, Darvasi, A, Domenici, E, Ehrenreich, H, Esko, T, Gejman, Pv, Gill, M, Hultman, Cm, Iwata, N, Jablensky, Av, Jönsson, Eg, Kendler, Ks, Knight, J, Lencz, T, Levinson, Df, Qs, Li, Liu, J, Malhotra, Ak, Mccarroll, Sa, Moran, Jl, Mowry, Bj, Nöthen, Mm, Ophoff, Ra, Owen, Mj, Palotie, A, Pato, Cn, Petryshen, Tl, Posthuma, D, Riley, Bp, Sham, Pc, Sklar, P, Clair, Ds, Weinberger, Dr, Wendland, Jr, Daly, Mj, Sullivan, Pf, O'Donovan, Mc

Publikováno v: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 276-289. Wiley-Liss Inc.
ISSUE=171B;STARTPAGE=276;ENDPAGE=289;ISSN=1552-4841;TITLE=American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
American journal of medical genetics. Part B, Neuropsychiatric genetics, 171BB(2), 276-289. Wiley-Liss Inc.
Bigdeli, T B, Ripke, S, Bacanu, S A, Lee, S H, Schizophrenia Working Group of the Psychiatric Genomics, U & Posthuma, D 2016, ' Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, no. 171B, 2, pp. 276-289 . https://doi.org/10.1002/ajmg.b.32402
American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 171(2), 276-289. Wiley
American journal of medical genetics: part B: neuropsychiatric genetics

Genome-wide association studies (GWAS) of schizophrenia have yielded more than 100 common susceptibility variants, and strongly support a substantial polygenic contribution of a large number of small allelic effects. It has been hypothesized that fam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41167d3bb4b14f55524797d8ec72f866
https://doi.org/10.1002/ajmg.b.32402

Treated Incidence of Psychotic Disorders in the Multinational EU-GEI Study

Autor: Jongsma HE, Gayer-Anderson C, Lasalvia A, Quattrone D, Mulè A, Szöke A, Selten JP, Turner C, Arango C, Tarricone I, Berardi D, Tortelli A, Llorca PM, de Haan L, Bobes J, Bernardo M, Sanjuán J, Santos JL, Arrojo M, Del-Ben CM, Menezes PR, Velthorst E, Murray RM, Rutten BP, Jones PB, van Os J, Morgan C, Kirkbride JB, European Network of National Schizophrenia Networks Studying Gene-Environment In

Publikováno v: JAMA Psychiatry
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::864b1413a9adaf7f0f2ea925ca8e0b36
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=1842

Antipsychotic treatment resistance in first-episode psychosis:prevalence, subtypes and predictors

Autor: Demjaha, A, Lappin, JM, Stahl, D, Patel, MX, MacCabe, JH, Howes, OD, Heslin, M, Reininghaus, Ulrich, Donoghue, K, Lomas, B, Charalambides, M, Onyejiaka, A, Fearon, P, Jones, P, Doody, G, Morgan, C, Dazzan, P, Murray, RM

Publikováno v: Demjaha, A, Lappin, J M, Stahl, D, Patel, M X, MacCabe, J H, Howes, O D, Heslin, M, Reininghaus, U A, Donoghue, K, Lomas, B, Charalambides, M, Onyejiaka, A, Fearon, P, Jones, P, Doody, G, Morgan, C, Dazzan, P & Murray, R M 2017, ' Antipsychotic treatment resistance in first-episode psychosis : prevalence, subtypes and predictors ', Psychological Medicine, vol. 47, no. 11, pp. 1981-1989 . https://doi.org/10.1017/S0033291717000435

BACKGROUND: We examined longitudinally the course and predictors of treatment resistance in a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic treatment. We hypothesized that antipsychotic treatment resistance i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7bfeb236b1d18043013ba518c02b951e
https://kclpure.kcl.ac.uk/ws/files/67495602/Antipsychotic_treatment_resistance_in_DEMJAHA_FirstonlineApril112017_GOLD_VoR_CC_BY_.pdf