Zobrazeno 1 - 10
of 1 022
pro vyhledávání: '"Murray B, Stein"'
Autor:
Alice Braun, Sudhanshu Shekhar, Daniel F. Levey, Peter Straub, Julia Kraft, Georgia M. Panagiotaropoulou, Karl Heilbron, Swapnil Awasthi, Rafael Meleka Hanna, Sarah Hoffmann, Maike Stein, Sophie Lehnerer, Philipp Mergenthaler, Abdelrahman G. Elnahas, Apostolia Topaloudi, Maria Koromina, Teemu Palviainen, Bergrun Asbjornsdottir, Hreinn Stefansson, Astros Th. Skuladóttir, Ingileif Jónsdóttir, Kari Stefansson, Kadri Reis, Tõnu Esko, Aarno Palotie, Frank Leypoldt, Murray B. Stein, Pierre Fontanillas, Estonian Biobank Research Team, andMe Research Team, Jaakko Kaprio, Joel Gelernter, Lea K. Davis, Peristera Paschou, Martijn R. Tannemaat, Jan J.G.M. Verschuuren, Gregor Kuhlenbäumer, Peter K. Gregersen, Maartje G. Huijbers, Frauke Stascheit, Andreas Meisel, Stephan Ripke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Myasthenia gravis (MG) is a rare autoantibody-mediated disease affecting the neuromuscular junction. We performed a genome-wide association study of 5708 MG cases and 432,028 controls of European ancestry and a replication study in 3989 case
Externí odkaz:
https://doaj.org/article/60cf6148fd9f44d284695ed5465db1c0
Autor:
Agaz H. Wani, Seyma Katrinli, Xiang Zhao, Nikolaos P. Daskalakis, Anthony S. Zannas, Allison E. Aiello, Dewleen G. Baker, Marco P. Boks, Leslie A. Brick, Chia-Yen Chen, Shareefa Dalvie, Catherine Fortier, Elbert Geuze, Jasmeet P. Hayes, Ronald C. Kessler, Anthony P. King, Nastassja Koen, Israel Liberzon, Adriana Lori, Jurjen J. Luykx, Adam X. Maihofer, William Milberg, Mark W. Miller, Mary S. Mufford, Nicole R. Nugent, Sheila Rauch, Kerry J. Ressler, Victoria B. Risbrough, Bart P. F. Rutten, Dan J. Stein, Murray B. Stein, Robert J. Ursano, Mieke H. Verfaellie, Eric Vermetten, Christiaan H. Vinkers, Erin B. Ware, Derek E. Wildman, Erika J. Wolf, Caroline M. Nievergelt, Mark W. Logue, Alicia K. Smith, Monica Uddin
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex disorders such as PTSD. Our goal was to develop and validate Methylation
Externí odkaz:
https://doaj.org/article/71292b89b7524386adcc89a2a04c6480
Autor:
Kaarina Kowalec, Arvid Harder, Casandra Dolovich, Kathryn C. Fitzgerald, Amber Salter, Yi Lu, Charles N. Bernstein, James M. Bolton, Gary Cutter, John D. Fisk, Joel Gelernter, Lesley A. Graff, Sara Hägg, Carol A. Hitchon, Daniel F. Levey, Fred D. Lublin, Kyla A. McKay, Scott Patten, Amit Patki, Murray B. Stein, Hemant K. Tiwari, Jerry S. Wolinsky, Ruth A. Marrie
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1393-1404 (2024)
Abstract Objective Comorbid anxiety occurs often in MS and is associated with disability progression. Polygenic scores offer a possible means of anxiety risk prediction but often have not been validated outside the original discovery population. We a
Externí odkaz:
https://doaj.org/article/44eb7cddf85b402196eae2d92bb7367c
Autor:
John K. Yue, John H. Kanter, Jason K. Barber, Michael C. Huang, Thomas A. van Essen, Mahmoud M. Elguindy, Brandon Foreman, Frederick K. Korley, Patrick J. Belton, Dana Pisică, Young M. Lee, Ryan S. Kitagawa, Mary J. Vassar, Xiaoying Sun, Gabriela G. Satris, Justin C. Wong, Adam R. Ferguson, J. Russell Huie, Kevin K.W. Wang, Hansen Deng, Vincent Y. Wang, Yelena G. Bodien, Sabrina R. Taylor, Debbie Y. Madhok, Michael A. McCrea, Laura B. Ngwenya, Anthony M. DiGiorgio, Phiroz E. Tarapore, Murray B. Stein, Ava M. Puccio, Joseph T. Giacino, Ramon Diaz-Arrastia, Hester F. Lingsma, Pratik Mukherjee, Esther L. Yuh, Claudia S. Robertson, David K. Menon, Andrew I.R. Maas, Amy J. Markowitz, Sonia Jain, David O. Okonkwo, Nancy R. Temkin, Geoffrey T. Manley, Jason E. Chung, Bukre Coskun, Shawn R. Eagle, Leila L. Etemad, Brian Fabian, Feeser V. Ramana, Shankar Gopinath, Christine J. Gotthardt, Ramesh Grandhi, Sabah Hamidi, Ruchira M. Jha, Christopher Madden, Randall Merchant, Lindsay D. Nelson, Richard B. Rodgers, Andrea L.C. Schneider, David M. Schnyer, Abel Torres-Espin, Joye X. Tracey, Alex B. Valadka, Ross D. Zafonte
Publikováno v:
The Lancet Regional Health. Americas, Vol 39, Iss , Pp 100915- (2024)
Summary: Background: Contemporary surgical practices for traumatic brain injury (TBI) remain unclear. We describe the clinical profile of an 18-centre US TBI cohort with cranial surgery. Methods: The prospective, observational Transforming Research a
Externí odkaz:
https://doaj.org/article/b9bb6c159a2e4ea2a1a70824491e0091
Autor:
Catherine L. Dempsey, Jingning Ao, Matthew W. Georg, Pablo A. Aliaga, David A. Brent, David M. Benedek, Kelly L. Zuromski, Matthew K. Nock, Steven G. Heeringa, Ronald C. Kessler, Murray B. Stein, Robert J. Ursano
Publikováno v:
Journal of Mood and Anxiety Disorders, Vol 7, Iss , Pp 100064- (2024)
Objectives: The rate of suicide increased in members of the United States Army since 2011 after the Iraq and Afghanistan wars and continues to be a major concern. In order to reverse this disturbing trend, it is vital to understand the risk and prote
Externí odkaz:
https://doaj.org/article/71afeb5a8058476ea2573bfa2726525d
Autor:
Adam X. Maihofer, Andrew Ratanatharathorn, Sian M. J. Hemmings, Karen H. Costenbader, Vasiliki Michopoulos, Renato Polimanti, Alex O. Rothbaum, Soraya Seedat, Elizabeth A. Mikita, CHARGE Inflammation Working Group, Psychiatric Genomics Consortium PTSD Working Group, Alicia K. Smith, Rany M. Salem, Richard A. Shaffer, Tianying Wu, Jonathan Sebat, Kerry J. Ressler, Murray B. Stein, Karestan C. Koenen, Erika J. Wolf, Jennifer A. Sumner, Caroline M. Nievergelt
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Observational studies suggest that posttraumatic stress disorder (PTSD) increases risk for various autoimmune diseases. Insights into shared biology and causal relationships between these diseases may inform intervention approaches to PTSD a
Externí odkaz:
https://doaj.org/article/3c74f81f134f46e6b77fd3adc226573a
Autor:
Ruoyu Tian, Tian Ge, Hyeokmoon Kweon, Daniel B. Rocha, Max Lam, Jimmy Z. Liu, Kritika Singh, Biogen Biobank Team, Daniel F. Levey, Joel Gelernter, Murray B. Stein, Ellen A. Tsai, Hailiang Huang, Christopher F. Chabris, Todd Lencz, Heiko Runz, Chia-Yen Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Nearly two hundred common-variant depression risk loci have been identified by genome-wide association studies (GWAS). However, the impact of rare coding variants on depression remains poorly understood. Here, we present whole-exome sequenci
Externí odkaz:
https://doaj.org/article/1855eca93fd445689cfb3f9e92f93eee
Autor:
Royce E. Clifford, Adam X. Maihofer, Chris Chatzinakos, Jonathan R. I. Coleman, Nikolaos P. Daskalakis, Marianna Gasperi, Kelleigh Hogan, Elizabeth A. Mikita, Murray B. Stein, Catherine Tcheandjieu, Francesca Telese, Yanning Zuo, Allen F. Ryan, Caroline M. Nievergelt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Tinnitus is a heritable, highly prevalent auditory disorder treated by multiple medical specialties. Previous GWAS indicated high genetic correlations between tinnitus and hearing loss, with little indication of differentiating signals. We p
Externí odkaz:
https://doaj.org/article/30de7f1a439945cab2722d0a874ce2a8
Autor:
Isabelle Austin-Zimmerman, Daniel F. Levey, Olga Giannakopoulou, Joseph D. Deak, Marco Galimberti, Keyrun Adhikari, Hang Zhou, Spiros Denaxas, Haritz Irizar, Karoline Kuchenbaecker, Andrew McQuillin, the Million Veteran Program, John Concato, Daniel J. Buysse, J. Michael Gaziano, Daniel J. Gottlieb, Renato Polimanti, Murray B. Stein, Elvira Bramon, Joel Gelernter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Sleep duration has been linked to a wide range of negative health outcomes and to reduced life expectancy. We present genome-wide association studies of short ( ≤ 5 h) and long ( ≥ 10 h) sleep duration in adults of European (N = 445,966)
Externí odkaz:
https://doaj.org/article/cab1fa0e42ad4eaaa9e305b317868c0f
Autor:
Holly B. Herberman Mash, Robert J. Ursano, Ronald C. Kessler, James A. Naifeh, Carol S. Fullerton, Pablo A. Aliaga, Hieu M. Dinh, Nancy A. Sampson, Tzu-Cheg Kao, Murray B. Stein
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Understanding mental health predictors of imminent suicide attempt (SA; within 30 days) among soldiers with depression and no prior suicide ideation (SI) can inform prevention and treatment. The current study aimed to identify soc
Externí odkaz:
https://doaj.org/article/f0a44438a4604d97811de6e595c79bc4