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Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis.

Autor: Middha P; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Thummalapalli R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Betti MJ; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Yao L; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Quandt Z; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco, San Francisco, CA, USA., Balaratnam K; Princess Margaret Cancer Centre, Toronto, ON, Canada., Bejan CA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Cardenas E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Falcon CJ; Fiona and Stanley Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Faleck DM; Gastroenterology, Hepatology & Nutrition Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gubens MA; Medical Oncology, University of California San Francisco, San Francisco, CA, USA.; Department of Medicine, Weill Cornell Medical Center, New York, NY, USA., Huntsman S; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Johnson DB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kachuri L; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University of Medicine, Stanford, CA, USA., Khan K; Princess Margaret Cancer Centre, Toronto, ON, Canada., Li M; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Lovly CM; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN, USA., Murray MH; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Patel D; Princess Margaret Cancer Centre, Toronto, ON, Canada., Werking K; Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Xu Y; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Zhan LJ; Princess Margaret Cancer Centre, Toronto, ON, Canada., Balko JM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Liu G; Princess Margaret Cancer Centre, Temerty School of Medicine, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Aldrich MC; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Schoenfeld AJ; Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York., Ziv E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, Center for Genes, Environment and Health and Institute for Human Genetics, University of California San Francisco, San Francisco, California.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Sep 13. Date of Electronic Publication: 2023 Sep 13.