Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Murphy Lam Yim Wan"'
Autor:
Hien Thi Tran, Murphy Lam Yim Wan, Ines Ambite, Michele Cavalera, Mario Grossi, Jaromir Háček, Parisa Esmaeili, António N. B. M. Carneiro, Arunima Chaudhuri, Shahram Ahmadi, Catharina Svanborg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Though new targeted therapies for colorectal cancer, which progresses from local intestinal tumors to metastatic disease, are being developed, tumor specificity remains an important problem, and side effects a major concern. Here, we show th
Externí odkaz:
https://doaj.org/article/5d4193e27f994f76a38cd041fc8fd884
Autor:
Ines Ambite, Thi Hien Tran, Daniel S. C. Butler, Michele Cavalera, Murphy Lam Yim Wan, Shahram Ahmadi, Catharina Svanborg
Publikováno v:
Pathogens, Vol 13, Iss 1, p 42 (2023)
Innate immunity is essential for the anti-microbial defense, but excessive immune activation may cause severe disease. In this study, immunotherapy was shown to prevent excessive innate immune activation and restore the anti-bacterial defense. E. col
Externí odkaz:
https://doaj.org/article/b944b834c8904e4c93330d4ab6e90837
Autor:
Antonín Brisuda, James C. S. Ho, Pancham S. Kandiyal, Justin T-Y. Ng, Ines Ambite, Daniel S. C. Butler, Jaromir Háček, Murphy Lam Yim Wan, Thi Hien Tran, Aftab Nadeem, Tuan Hiep Tran, Anna Hastings, Petter Storm, Daniel L. Fortunati, Parisa Esmaeili, Hana Novotna, Jakub Horňák, Y. G. Mu, K. H. Mok, Marek Babjuk, Catharina Svanborg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Partially unfolded alpha-lactalbumin forms an oleic acid complex with antitumorigenic properties. Here, the authors define a structurally flexible, peptide-based oleate complex and report a phase I/II clinical trial where this complex is used to trea
Externí odkaz:
https://doaj.org/article/8bab807c461e46258408ec0d77b8d766
Publikováno v:
Process Biochemistry. 130:272-280
Autor:
Daniel Butler, Ines Ambite, Murphy Lam Yim Wan, Thi Hien Tran, Björn Wullt, Catharina Svanborg
Publikováno v:
Nature Reviews Urology. 19:419-437
Innovative solutions are needed for the treatment of bacterial infections, and a range of antibacterial molecules have been explored as alternatives to antibiotics. A different approach is to investigate the immune system of the host for new ways of
Autor:
Tran Thi Hien, Ines Ambite, Murphy Lam Yim Wan, Michele Cavalera, Parisa Esmaeili, Arunima Chaudhuri, Samudra Sabari, Marek Babjuk, Catharina Svanborg
Publikováno v:
International Journal of Cancer.
Schisandrin B (Sch-B) is a predominant bioactive lignan in the fruit of a traditional Chinese medicinal plantSchisandra Chinensiswith widely reported anti-cancer properties. Using a xenograft mouse model of colorectal cancer (CRC), we showed potent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9743490afb79c87d248b520e9d45ad45
https://doi.org/10.1101/2022.11.28.518277
https://doi.org/10.1101/2022.11.28.518277
Autor:
Thi Hien Tran, Petter Storm, Kenneth Hun Mok, Antonin Brisuda, Catharina Svanborg, Anna Hastings, Justin Tze Yang Ng, Murphy Lam Yim Wan, Marek Babjuk, Pancham S. Kandiyal, Tuan Hiep Tran, James C. S. Ho, Hana Novotna, Daniel S.C. Butler, Yuguang Mu, Jaromir Hacek, Jakub Horňák, Aftab Nadeem, Ines Ambite, Daniel L. Fortunati, Parisa Esmaeili
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Partially unfolded alpha-lactalbumin forms the oleic acid complex HAMLET, with potent tumoricidal activity. Here we define a peptide-based molecular approach for targeting and killing tumor cells, and evidence of its clinical potential (ClinicalTrial
Publikováno v:
Critical reviews in food science and nutrition. 62(24)
Endocrine-disrupting compounds (EDCs) are ubiquitous substances that are found in our everyday lives, including pesticides, plasticizers, pharmaceutical agents, personal care products, and also in food products and food packaging. Increasing epidemio
Autor:
Charlotte Welinder, Thi Hien Tran, Shahram Ahmadi, Johannes Putze, Ulrich Dobrindt, Murphy Lam Yim Wan, Sing Ming Chao, Catharina Svanborg, Daniel S.C. Butler, Sven Kjellström, Caterina Cafaro, Ines Ambite
Publikováno v:
Nature Biotechnology
Is the oncogene MYC upregulated or hyperactive? In the majority of human cancers, finding agents that target c-MYC has proved difficult. Here we report specific bacterial effector molecules that inhibit cellular MYC (c-MYC) in human cells. We show th