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Stability of Ti 3 C 2 T x MXene Films and Devices under Clinical Sterilization Processes.

Autor: Averbeck SR; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Xu D; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Murphy BB; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Shevchuk K; Department of Material Science and Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States.; A.J Drexel Nanomaterials Institute, Drexel University, Philadelphia, Pennsylvania 19104, United States., Shankar S; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Anayee M; Department of Material Science and Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States.; A.J Drexel Nanomaterials Institute, Drexel University, Philadelphia, Pennsylvania 19104, United States., Der Torossian Torres M; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Departments of Psychiatry and Microbiology, Perelman School of Medicine University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Beauchamp MS; Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., de la Fuente-Nunez C; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Departments of Psychiatry and Microbiology, Perelman School of Medicine University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Gogotsi Y; Department of Material Science and Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States.; A.J Drexel Nanomaterials Institute, Drexel University, Philadelphia, Pennsylvania 19104, United States., Vitale F; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, United States.

Publikováno v: ACS nano [ACS Nano] 2023 May 23; Vol. 17 (10), pp. 9442-9454. Date of Electronic Publication: 2023 May 12.

Vitamin C-reduced graphene oxide improves the performance and stability of multimodal neural microelectrodes.

Autor: Murphy BB; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Apollo NV; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Unegbu P; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Posey T; Department of Biomedical Engineering, University of South Carolina, Columbia, SC 29206, USA., Rodriguez-Perez N; School of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, AZ 85281, USA., Hendricks Q; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA., Cimino F; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA., Richardson AG; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Vitale F; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, PA 19146, USA.

Publikováno v: IScience [iScience] 2022 Jun 22; Vol. 25 (7), pp. 104652. Date of Electronic Publication: 2022 Jun 22 (Print Publication: 2022).

MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation.

Autor: Driscoll N; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Erickson B; Department of Psychology, Drexel University, Philadelphia, PA 19104, USA., Murphy BB; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Richardson AG; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Robbins G; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, PA 19104, USA., Apollo NV; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Mentzelopoulos G; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Mathis T; Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.; A.J. Drexel Nanomaterials Institute, Drexel University, Philadelphia, PA 19104, USA., Hantanasirisakul K; Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.; A.J. Drexel Nanomaterials Institute, Drexel University, Philadelphia, PA 19104, USA., Bagga P; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Gullbrand SE; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA.; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Sergison M; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Reddy R; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA., Wolf JA; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Chen HI; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Lucas TH; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Dillingham TR; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, PA 19104, USA., Davis KA; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA., Gogotsi Y; Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.; A.J. Drexel Nanomaterials Institute, Drexel University, Philadelphia, PA 19104, USA., Medaglia JD; Department of Psychology, Drexel University, Philadelphia, PA 19104, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Neurology, Drexel University, Philadelphia, PA 19104, USA., Vitale F; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, PA 19104, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2021 Sep 22; Vol. 13 (612), pp. eabf8629. Date of Electronic Publication: 2021 Sep 22.

Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale.

Autor: Driscoll N; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Rosch RE; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.; Department of Paediatric Neurology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Murphy BB; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA., Ashourvan A; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA., Vishnubhotla R; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA., Dickens OO; Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA, USA., Johnson ATC; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA., Davis KA; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Litt B; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bassett DS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Electrical & Systems Engineering, University of Pennsylvania, Philadelphia, PA, USA.; Santa Fe Institute, Santa Fe, NM, USA., Takano H; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. takanoh@email.chop.edu.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. takanoh@email.chop.edu., Vitale F; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA. vitalef@pennmedicine.upenn.edu.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA. vitalef@pennmedicine.upenn.edu.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. vitalef@pennmedicine.upenn.edu.; Department of Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, PA, USA. vitalef@pennmedicine.upenn.edu.

Publikováno v: Communications biology [Commun Biol] 2021 Jan 29; Vol. 4 (1), pp. 136. Date of Electronic Publication: 2021 Jan 29.