Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Autor: Wang, Z, Aguilar, EG, Luna, JI, Dunai, C, Khuat, LT, Le, CT, Mirsoian, A, Minnar, CM, Stoffel, KM, Sturgill, IR, Grossenbacher, SK, Withers, SS, Rebhun, RB, Hartigan-O’Connor, DJ, Méndez-Lagares, G, Tarantal, AF, Isseroff, RR, Griffith, TS, Schalper, KA, Merleev, A, Saha, A, Maverakis, E, Kelly, K, Aljumaily, R, Ibrahimi, S, Mukherjee, S, Machiorlatti, M, Vesely, SK, Longo, DL, Blazar, BR, Canter, RJ, Murphy, WJ, Monjazeb, AM

Publikováno v: Nature medicine, vol 25, iss 1
Hepatobiliary Surg Nutr
Wang, Z; Aguilar, EG; Luna, JI; Dunai, C; Khuat, LT; Le, CT; et al.(2018). Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. Nature Medicine. doi: 10.1038/s41591-018-0221-5. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/14v385n0

© 2018, The Author(s), under exclusive licence to Springer Nature America, Inc. The recent successes of immunotherapy have shifted the paradigm in cancer treatment, but because only a percentage of patients are responsive to immunotherapy, it is imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f6c29817d4fa55c123dc8a25111d8a1f
https://escholarship.org/uc/item/14v385n0

Induction of CD4(+) T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta(1)

Autor: Zeller JC, Panoskaltsis Mortari A, Murphy WJ, Ruscetti FW, Narula S, Blazar BR, RONCAROLO , MARIA GRAZIA

Induction and maintenance of Ag-specific tolerance are pivotal for immune homeostasis, prevention of autoimmune disorders, and the goal of transplantation. Recent studies suggest that certain cytokines, notably IL-10 and TGF-beta, may play a role in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::0c9792b6b2f4a4093a35c328cd599c32

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