Výsledky vyhledávání - "Murphy, P.R."

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells

Autor: Wong, C., Darby, J.M., Murphy, P.R., Pinfold, T.L., Lennard, P.R., Woods, G.M., Lyons, A.B., Flies, A.S.

Immune checkpoint immunotherapy is a pillar of human oncology treatment with potential for non-human species. The first checkpoint immunotherapy approved for human cancers targeted the CTLA4 protein. CTLA4 can inhibit T cell activation by capturing a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::c5de31e6fa810cde108218c77d4d1b19
https://hdl.handle.net/1887/3628181

Zobrazit plný text záznamu

Generation and testing of fluorescent adaptable simple theranostic (FAST) proteins

Autor: Flies, A.S., Darby, J.M., Murphy, P.R., Pinfold, T.L., Patchett, A.L., Lennard, P.R.

This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins that can be secreted from mammalian cell lines. This builds on many other recombinant protein and fluorescent protein techniques, but is among the first to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::18d4b4a5178f561014308661eaf1d08f
https://hdl.handle.net/1887/3627034

Zobrazit plný text záznamu

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

Autor: Flies, A.S., Darby, J.M., Lennard, P.R., Murphy, P.R., Ong, C.E.B., Pinfold, T.L., Luca, A. de, Lyons, A.B., Woods, G.M., Patchett, A.L.

Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their lifetime, compared to less than 10% for most species. In addition, devils are affected by two of the three known transmissible cancers in mammals. Immune checkpo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::f2a765e1cc37828c58db381c6d952f52
https://hdl.handle.net/1887/3627032

Zobrazit plný text záznamu