Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Murli Narayan"'
Autor:
Christian Brander, David T. Scadden, Todd J. Suscovich, Sheila C. Dollard, Tania M. Welzel, Daniel Kaufmann, Kenneth M. Kaye, Elizabeth E. Brown, Jeffrey N. Martin, Fred Wang, John V. Chisholm, Leah M. Henry, Murli Narayan, Florian Bihl, Tauheed Zaman
Publikováno v:
Journal of Virology. 81:4904-4908
The cellular immunity against Kaposi's sarcoma-associated herpesvirus (KSHV) is poorly characterized and has not been compared to T-cell responses against other human herpesviruses. Here, novel and dominant targets of KSHV-specific cellular immunity
Publikováno v:
Journal of Virology. 77:12829-12840
The Rex protein of human T-cell leukemia virus (HTLV) acts posttranscriptionally to induce the cytoplasmic expression of the unspliced and incompletely spliced viral RNAs encoding the viral structural and enzymatic proteins and is therefore essential
Publikováno v:
Journal of Molecular Biology. 321:807-819
DNA helicases are molecular motors that use the energy from NTP hydrolysis to drive the process of duplex DNA strand separation. Here, we measure the translocation and energy coupling efficiency of a replicative DNA helicase from bacteriophage T7 tha
Publikováno v:
Journal of Virology. 74:2655-2662
Human T-cell leukemia virus (HTLV) Tax protein has been implicated in the HTLV oncogenic process, primarily due to its pleiotropic effects on cellular genes involved in growth regulation and cell cycle control. To date, several approaches attempting
Publikováno v:
International Journal of Cancer. 72:728-734
To determine whether the multidrug-resistance-gene product phospho-glycoprotein (P-gp) is implicated in progression of oral tumours and/or drug resistance, the expression of P-gp was examined in different stages of oral oncogenesis using monoclonal a
Autor:
Steven H. Kleinstein, Lyndsay Harris, Ian E. Krop, Kimberly Lezon-Geyda, Murli Narayan, David Tuck, Emmett Sprecher, Sudipa Sarkar, Eric P. Winer
Publikováno v:
BCB
Human epidermal growth factor receptor 2 amplified (HER2+) breast cancer is common and aggressive. Trastuzumab is a targeted therapy to the HER2 cell surface receptor and has greatly improved prognosis for HER2+ breast cancer patients, but trastuzuma
Publikováno v:
Breast Cancer Research : BCR
Introduction HER2 and estrogen receptor (ER) are important in breast cancer and are therapeutic targets of trastuzumab (Herceptin) and tamoxifen, respectively. Retinoids inhibit breast cancer growth, and modulate signaling by HER2 and ER. We hypothes
Autor:
Murli Narayan, Lyndsay Harris, Jason A. Wilken, Andre T. Baron, Nita J. Maihle, Kimberly D. Kimbler
Publikováno v:
Cancer research. 69(6)
Although trastuzumab (Herceptin) is an important advance in the treatment of breast cancer, a significant proportion of patients do not respond to trastuzumab either alone or in combination with chemotherapy. In this study, we observe that epidermal
The function of the human T-cell leukemia virus (HTLV) Rex phosphoprotein is to increase the level of the viral structural and enzymatic gene products expressed from the incompletely spliced viral RNAs containing the Rex-responsive element. The phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab683bd2f8e07f611d566880261a69f
https://europepmc.org/articles/PMC115089/
https://europepmc.org/articles/PMC115089/
Autor:
Susan Radke, Yoon Jung Kim, Lyndsay Harris, Amanika Kumar, Murli Narayan, Kimberly Geyda, Katharine R. Cecchini, Tae Hoon Kim, David Tuck
Publikováno v:
Cancer Research. 70:2992-2992
Inhibition of cancer cell growth by histone deacetylase (HDAC) inhibitors has been observed in a number of malignancies. Multiple mechanisms have been proposed to explain the cancer-specific cytotoxic effect of HDAC inhibition, including transcriptio