Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Muris Humo"'
Autor:
Léa J. Becker, Clémentine Fillinger, Robin Waegaert, Sarah H. Journée, Pierre Hener, Beyza Ayazgok, Muris Humo, Meltem Karatas, Maxime Thouaye, Mithil Gaikwad, Laetitia Degiorgis, Marie des Neiges Santin, Mary Mondino, Michel Barrot, El Chérif Ibrahim, Gustavo Turecki, Raoul Belzeaux, Pierre Veinante, Laura A. Harsan, Sylvain Hugel, Pierre-Eric Lutz, Ipek Yalcin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract While depression and chronic pain are frequently comorbid, underlying neuronal circuits and their psychopathological relevance remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking the basolateral amy
Externí odkaz:
https://doaj.org/article/79edb28876214399bf2915cb6fdcd98c
Autor:
Léa J Becker, Clémentine Fillinger, Robin Waegaert, Pierre Hener, Beyza Ayazgok, Muris Humo, Sarah H Journée, Meltem Karatas, Laetitia Degiorgis, Marie des Neiges Santin, Mary Mondino, Michel Barrot, El Chérif Ibrahim, Gustavo Turecki, Raoul Belzeaux, Pierre Veinante, Laura A Harsan, Sylvain Hugel, Pierre-Eric Lutz, Ipek Yalcin
While depression and chronic pain are frequently comorbid, underlying neuronal circuits, and their relevance for the understanding of psychopathology, remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::208c90ab4996acd0d348066196b9937d
https://doi.org/10.1101/2022.08.09.503276
https://doi.org/10.1101/2022.08.09.503276
Publikováno v:
Cell and Tissue Research. 377:21-43
The increasing number of individuals with comorbidities poses an urgent need to improve the management of patients with multiple co-existing diseases. Among these comorbidities, chronic pain and mood disorders, two long-lasting disabling conditions t
Autor:
Beyza Ayazgök, Tomi Rantamäki, Elisabeth Waltisperger, Muris Humo, Léa J. Becker, Ipek Yalcin
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 100, pp.109898. ⟨10.1016/j.pnpbp.2020.109898⟩
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 100, pp.109898. ⟨10.1016/j.pnpbp.2020.109898⟩
International audience; Chronic pain produces psychologic distress, which often leads to mood disorders such as depression. Co-existing chronic pain and depression pose a serious socioeconomic burden and result in disability affecting millions indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca7d7a720b225bd79a79d814237e642
https://hal.archives-ouvertes.fr/hal-03001563/file/PNP_2020_accepted.pdf
https://hal.archives-ouvertes.fr/hal-03001563/file/PNP_2020_accepted.pdf
Publikováno v:
Cell Adhesion & Migration. 9:417-421
Growth cone guidance is driven by attractive and repulsive signaling cues. Until recently, repulsive signaling by semaphorins was thought to be mediated through Plexin receptors, whereas Slits-induced repulsion was solely mediated through Robo recept
Autor:
Michel Barrot, Ipek Yalcin, François Daubeuf, Nelly Frossard, Frédéric Bihel, Martine Schmitt, Patrick Wagner, Jean-Jacques Bourguignon, Maud Bollenbach, Léa J. Becker, Baptiste Letellier, Adeline Obrecht, Muris Humo, Eric Salvat, Pascal Villa
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
4-phenylpyridin-2-yl-guanidine (5b): a new inhibitor of the overproduction of pro-inflammatory cytokines (TNFα and Il1β) was identified from a high-throughput screening of a chemical library on human peripheral blood mononuclear cells (PBMCs) after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff5ae2e3d53d5dcbce7ceeae4c559a8
https://hal.archives-ouvertes.fr/hal-02323729
https://hal.archives-ouvertes.fr/hal-02323729
Autor:
Lutz Hein, Muris Humo, Samuel Leman, Ipek Yalcin, Ralf Gilsbach, Elisabeth Waltisperger, Catherine Belzung, Anne-Laurence Boutillier, Michel Barrot, Florent Barthas, Meltem Karatas
Publikováno v:
Biological Psychiatry
Biological Psychiatry, Elsevier, 2017, 82 (5), pp.370-379. ⟨10.1016/j.biopsych.2017.01.019⟩
Biological Psychiatry, 2017, 82 (5), pp.370-379. ⟨10.1016/j.biopsych.2017.01.019⟩
Biological Psychiatry, Elsevier, 2017, 82 (5), pp.370-379. ⟨10.1016/j.biopsych.2017.01.019⟩
Biological Psychiatry, 2017, 82 (5), pp.370-379. ⟨10.1016/j.biopsych.2017.01.019⟩
Background Depression is frequently associated with chronic pain or chronic stress. Among cortical areas, the anterior cingulate cortex (ACC, areas 24a and 24b) appears to be important for mood disorders and constitutes a neuroanatomical substrate fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccf9510534d0244ea3a81f22181bb83
https://hal.archives-ouvertes.fr/hal-02106543
https://hal.archives-ouvertes.fr/hal-02106543