Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial.

Autor: Tomazini BM; Hcor Research Institute, São Paulo (SP), Brazil.; Brazilian Research in Intensive Care Network (BRICNet), São Paulo (SP), Brazil.; Hospital Sírio-Libanês, São Paulo (SP), Brazil., Tramujas L; Hcor Research Institute, São Paulo (SP), Brazil., Medrado FA Junior; Hcor Research Institute, São Paulo (SP), Brazil., Gomes SPDC; Hcor Research Institute, São Paulo (SP), Brazil., Negrelli KL; Hcor Research Institute, São Paulo (SP), Brazil., Murinize GS; Hcor Research Institute, São Paulo (SP), Brazil., Santos RHN; Hcor Research Institute, São Paulo (SP), Brazil., Vianna BMP; Hcor Research Institute, São Paulo (SP), Brazil., Piotto BF; Hcor Research Institute, São Paulo (SP), Brazil., Veiga TS; Hcor Research Institute, São Paulo (SP), Brazil., Santos BRD; Hcor Research Institute, São Paulo (SP), Brazil., Peneluppi Horak AC; Hcor Research Institute, São Paulo (SP), Brazil., Lemos OMC; Hospital do Coração (HCor), São Paulo (SP), Brazil., Lopes MA; Hcor Research Institute, São Paulo (SP), Brazil., Olicheski BB; Hospital do Coração (HCor), São Paulo (SP), Brazil., Campones DL; Hospital do Coração (HCor), São Paulo (SP), Brazil., Peixoto LAA; Hospital do Coração (HCor), São Paulo (SP), Brazil., Basilio ADAC; Hospital do Coração (HCor), São Paulo (SP), Brazil., Gebara OCE; Hospital Santa Paula, São Paulo (SP), Brazil., Lopes ATA; Hospital Santa Paula, São Paulo (SP), Brazil., Saconato H; Hospital Santa Paula, São Paulo (SP), Brazil., Valeis N; Hcor Research Institute, São Paulo (SP), Brazil., Miranda TA; Hcor Research Institute, São Paulo (SP), Brazil., Laranjeira LN; Hcor Research Institute, São Paulo (SP), Brazil., Santucci EV; Hcor Research Institute, São Paulo (SP), Brazil., Carlin AF; Departments of Pathology and Medicine, University of California, San Diego, La Jolla, California, United States of America., Esko JD; Department of Cellular and Molecular Medicine and Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America., Gordts PLSM; Department of Medicine, and Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, United States of America., Tsimikas S; Division of Cardiovascular Medicine, Sulpizio Cardiovascular Center, University of California San Diego, La Jolla, California, United States of America., Cavalcanti AB; Hcor Research Institute, São Paulo (SP), Brazil.; Brazilian Research in Intensive Care Network (BRICNet), São Paulo (SP), Brazil.

Publikováno v: PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0299197. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).