Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Murilo L Bello"'
Autor:
Murilo L Bello, Aridio M Junior, Bárbara A Vieira, Luiza R S Dias, Valéria P de Sousa, Helena C Castro, Carlos R Rodrigues, Lucio M Cabral
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121110 (2015)
Layered drug delivery carriers are current targets of nanotechnology studies since they are able to accommodate pharmacologically active substances and are effective at modulating drug release. Sodium montmorillonite (Na-MMT) is a clay that has suita
Externí odkaz:
https://doaj.org/article/02b6c64408ed4b3dbe889bed3fc4a04b
Autor:
Daniel T. G. Gonzaga, Felipe H. Oliveira, N. L. von Ranke, G. Q. Pinho, Juliana P. Salles, Murilo L. Bello, Carlos R. Rodrigues, Helena C. Castro, Hellen V. C. M. de Souza, Caroline R. C. Reis, Rennan P. P. Leme, João C. M. Mafra, Luiz C. S. Pinheiro, Lucas V. B. Hoelz, Nubia Boechat, Robson X. Faria
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay),
Externí odkaz:
https://doaj.org/article/9ab312f8957145ae9c80d75e8662765a
Autor:
Juliana P S, Dos Santos, Ruan Carlos B, Ribeiro, Juliana V, Faria, Murilo L, Bello, Carolina G S, Lima, Fernanda P, Pauli, Amanda A, Borges, David R, Rocha, Matheus G, Moraes, Luana S M, Forezi, Vitor F, Ferreira, Robson X, Faria, Fernando de C, da Silva
Publikováno v:
Journal of bioenergetics and biomembranes. 54(5-6)
The P2X7 receptor (P2X7R) is an ion channel that promotes the passage of ions through the membrane through brief stimulation once activated by ATP, its endogenous opener. However, prolonged stimulation with ATP, which occurs in pathological processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::659a5d3144030c9382cea82f2f629710
https://pubmed.ncbi.nlm.nih.gov/36070071
https://pubmed.ncbi.nlm.nih.gov/36070071
Autor:
Murilo L. Bello, Arídio M. Junior, Caroline A. Freitas, Marina L.A. Moreira, Juliana P. da Costa, Matheus A. de Souza, Bianca A.M.C. Santos, Valeria P. de Sousa, Helena C. Castro, Carlos R. Rodrigues, Lucio M. Cabral
Publikováno v:
European Journal of Pharmaceutical Sciences. 175:106222
The drug delivery systems are an important strategy of pharmaceutical technology to modulate undesirable properties, increasing efficacy, and reducing the side effects of active pharmaceutical ingredients (API). The sustained release is a type of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62939f5326f6df0a154f70d746ad79a8
https://doi.org/10.1016/j.ejps.2022.106222
https://doi.org/10.1016/j.ejps.2022.106222
Autor:
Robson X. Faria, Vinícius R. Campos, Raíssa Maria Dos Santos Galvão, Murilo L. Bello, Vitor F. Ferreira, Fernanda P. Pauli, Thais de B. da Silva, Luana da S. M. Forezi, Kathya N.K. Ji, Ana F.M. Faria, Jackson A. L. C. Resende, Fernando de C. da Silva
Publikováno v:
Bioorganic Chemistry. 116:105250
1,2,3-triazole heterocycles stand out in medicinal chemistry for having great structural diversity and bioactivities. In this study, two series of triazoles were synthesized. One was obtained by the 1,3-dipolar cycloaddition reaction between ethyl cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e089f1f346680e8cd1971f0b716b9840
https://doi.org/10.1016/j.bioorg.2021.105250
https://doi.org/10.1016/j.bioorg.2021.105250
Autor:
RAQUEL R.S. SALVADOR, MURILO L. BELLO, IGOR R.L. BARRETO, MARIA A.F. VERA, ESTELA M.F. MURI, SÉRGIO DE ALBUQUERQUE, LUIZA R.S. DIAS
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0
ABSTRACT This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds wer
Externí odkaz:
https://doaj.org/article/e9ebd4f728da48ed83c5b83a72f04335
Autor:
SIMONE S.S. OLIVEIRA, MURILO L. BELLO, CARLOS R. RODRIGUES, PAULA L. DE AZEVEDO, MARIA C.K.V. RAMOS, FRANCISCO R. DE AQUINO-NETO, SORELE B. FIAUX, LUIZA R.S. DIAS
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0
ABSTRACT This study presents the bioreduction of six β-ketoesters by whole cells of Kluyveromyces marxianus and molecular investigation of a series of 13 β-ketoesters by hologram quantitative structure-activity relationship (HQSAR) in order to rela
Externí odkaz:
https://doaj.org/article/6345130ea2a244668eafbc4bc0c0f902