Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Murilo F. Cerri"'
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Synthesis, Antitumor Activity and Docking of 2,3-(Substituted)-1,4-Naphthoquinone Derivatives Containing Nitrogen, Oxygen and Sulfur
Autor: Wanderson Romão, Alex Gutterres Taranto, Sandro J. Greco, Klesia Pirola Madeira, Leticia Batista Azevedo Rangel, Renata Dalmaschio Daltoé, Murilo F. Cerri, Valdemar Lacerda Júnior, Maicon Delarmelina
Publikováno v: Journal of the Brazilian Chemical Society v.26 n.9 2015
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 26, Issue: 9, Pages: 1804-1816, Published: SEP 2015
Eleven 2,3-(substituted)-1,4-naphthoquinone derivatives were synthesized in yields ranging from 52-89%. These derivatives were evaluated for their cytotoxic effects on human lungs (H460), triple-negative breast (MDA-MB-231) and ovarian (A2780) cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881348f65800d07a422584edb140fda2
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000901804
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3
Abstract 463: Evaluation of relative expression of SLC34A2/NaPi-IIb in lung cancer cell lines treated with estrogen and PKC and PKA pathway modulators
Autor: Lucas Cunha Dias de Rezende, Marcela F. Paes, Nayara G. Tessarollo, Leticia Batista Azevedo Rangel, Klesia Pirola Madeira, Murilo F. Cerri, Renata Dalmaschio Daltoé, Ian Victor Silva
Publikováno v: Cancer Research. 74:463-463
Background: Lung cancer (LC) represents a major health challenge worldwide, being the leading cause of cancer-related deaths in both men and women. SLC34A2 is a member of the solute carrier family and encodes the type IIb sodium phosphate cotransport
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40890f3e92c3f2d661dd285869fed5ff
https://doi.org/10.1158/1538-7445.am2014-463
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4
Abstract 3343: Anomalous expression of claudin 16 in ovarian cancer: Role of PKC, PI3K and estrogen
Autor: Klesia Pirola Madeira, Renata Dalmaschio Daltoé, Nayara G. Tessarollo, Marcela F. Paes, Leticia Batista Azevedo Rangel, Alice Laschuk Herlinger, Ian Victor Silva, Murilo F. Cerri
Publikováno v: Cancer Research. 74:3343-3343
Background: We have demonstrated that 63% of primary epithelial ovarian cancer (EOC) anomalously overexpressed CLDN16 in the cell cytoplasm, regardless of tumor histological type or grade, thus suggesting that this is an early event in EOC developmen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3032ae2be395f8dea910e435fd79cfe3
https://doi.org/10.1158/1538-7445.am2014-3343
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Abstract 2626: Novel naphtoquinone PIC21 targets PI3K in triple negative breast cancer cell line
Autor: Renata D. Daltoe, Klesia P. Madeira, Murilo F. Cerri, João F. Allochio Filho, Maicon Delarmelina, Marcella L. Porto, Silvana S. Meirelles, Ian V. Silva, Sandro J. Greco, Leticia B A Rangel
Publikováno v: Cancer Research. 74:2626-2626
Background: Triple negative breast cancer (TNBC) is a heterogeneous subgroup (ER-, PR-, and HER2-) of aggressive breast cancer, which poor prognosis is partially due to chemoresistance to available drugs. We have synthesized and screened 43 novel nap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bffd5fe5e4a65fd30f8b9543eb8bda75
https://doi.org/10.1158/1538-7445.am2014-2626
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Abstract 924: In vitro study of the potential antineoplastic effect of synthetic naphthoquinones in cisplatin-resistant ovarian cancer lineage
Autor: Leticia Ba Rangel, Murilo F. Cerri, João F. Allochio-Filho, Iuri C. Valadão, Klesia Pirola Madeira, Isabella dos Santos Guimarães, Renata Dalmaschio Daltoé, Sarah Fernandes Teixeira, Lucas Cd Rezende, Sandro J. Greco, Alice Laschuk Herlinger
Publikováno v: Cancer Research. 72:924-924
Background: Cancer development has been associated with alterations in polyamine biosynthesis and metabolism, which induce cell proliferation, angiogenesis, expression of genes related to tumor invasion and metastasis; whereas inhibit apoptosis. Base
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a23a4148abd1604a5a746649f1d8f3e
https://doi.org/10.1158/1538-7445.am2012-924
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10
A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil
Autor: Leticia Ba Rangel, Luciana B Coitinho, Alex Assis de Carvalho, Letícia Soncini Souza, Murilo F. Cerri, Alice Laschuk Herlinger, Klesia Pirola Madeira, Gabriela Modenesi Sirtoli, Renata Dalmaschio Daltoé, Débora Silva, Marcela F. Paes, Ian Victor Silva, Lucas Cd Rezende, Ana Cristina Nascimento Chiaradia
Publikováno v: Journal of Ovarian Research, Vol 4, Iss 1, p 14 (2011)
Journal of Ovarian Research
Background Ovarian cancer is sixth most common cancer among women and the leading cause of death in women with gynecological malignancies. Despite the great impact ovarian cancer has on women's health and its great impact in public economy, Brazil st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b187b48ea60a6f7eea73d7a8cb8627
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