Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Murielle Rinaldi-Carmona"'
Autor:
Laurent Boulu, Francis Barth, Gérard Fabre, Murielle Rinaldi-Carmona, Christian Congy, Olivier Finance, Freddy Sadoun, Laurent Hortala
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4573-4577
A new series of 2,3-diarylpyrroles have been prepared and evaluated as CB(1) antagonists. Modulation of the topological polar surface area allowed the identification of high affinity peripherally-restricted CB(1) antagonists. Compound 11, obtained af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d71b0218d55df7e2645fe0f3adb929c
https://doi.org/10.1016/j.bmcl.2010.06.017
https://doi.org/10.1016/j.bmcl.2010.06.017
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 191:933-940
RESUME Le systeme endocannabinoide (EC) est un systeme physiologique qui jour un role important dans la regulation de nombreuses fonctions biologiques tant au niveau central que peripherique. Dans certaines conditions, il devient hyperactif et peut i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c8e7812cbfaced9e28d705a4d60e18
https://doi.org/10.1016/s0001-4079(19)33031-6
https://doi.org/10.1016/s0001-4079(19)33031-6
Autor:
Frank Tourrel, Thierry Durand, Mikhail Bobrov, Agnès Muller, Oumeya Adjali, Olivier Payet, Vladimir V. Bezuglov, Natalia Gretskaya, Murielle Rinaldi-Carmona, Laurence Maurin
Publikováno v:
Life Sciences. 77:1425-1440
The pharmacological and neuroprotective properties of two ester analogs of the endocannabinoids, arachidonoylethyleneglycol (AA-EG) and α,α,-dimethyl arachidonoylethyleneglycol (DMA-EG), were investigated. We examined the interaction of both compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841e2ca2ada9e5677697dffde14b5154
https://doi.org/10.1016/j.lfs.2005.02.011
https://doi.org/10.1016/j.lfs.2005.02.011
Autor:
Jean-Pierre Maffrand, Marco Landi, Tiziano Croci, Gérard Le Fur, Murielle Rinaldi-Carmona, Luciano Manara
Publikováno v:
European Journal of Pharmacology. 450:77-83
We studied the delay in gastric emptying and gastrointestinal transit induced by the cannabinoid receptor agonists (+)-WIN 55,212-2 (R(+)-[2,3-dihydro-5-methyl-3-[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)methanone me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5533f688ef81b0c62c56621a32f5095
https://doi.org/10.1016/s0014-2999(02)02053-8
https://doi.org/10.1016/s0014-2999(02)02053-8
Autor:
John L. Musachio, Francis Barth, William B. Mathews, Robert F. Dannals, Murielle Rinaldi-Carmona, Hayden T. Ravert, Richard A. Frank
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 42:589-596
A cannabinoid receptor antagonist, SR144385, has been labeled with fluorine-18. [18F] SR144385 was synthesized in a multi-step reaction in which fluorine-18 was introduced by nucleophilic halogen displacement on a bromo precursor. The fluorine-18 lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98ea80f69d46f991d09d4e2413a920e
https://doi.org/10.1002/(sici)1099-1344(199906)42:6<589::aid-jlcr219>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199906)42:6<589::aid-jlcr219>3.0.co
Autor:
M. Portier, Laura Milligan, Francis Barth, Johannes Lupker, Pierre Casellas, Florence Pecceu, Xavier Canat, Gérard Le Fur, Sylvie Perrachon, Jean-Pierre Maffrand, Murielle Rinaldi-Carmona, Monsif Bouaboula, Bernard Calandra
Publikováno v:
Journal of Biological Chemistry. 272:22330-22339
In the present study, we showed that Chinese hamster ovary (CHO) cells transfected with human central cannabinoid receptor (CB1) exhibit high constitutive activity at both levels of mitogen-activated protein kinase (MAPK) and adenylyl cyclase. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2d2795db8da78ee363a8f9c34cd530
https://doi.org/10.1074/jbc.272.35.22330
https://doi.org/10.1074/jbc.272.35.22330
Autor:
Pascual Ferrara, David Shire, Daniel Caput, Bernard Calandra, Odile Bonnin-Cabanne, Gérard Le Fur, Murielle Rinaldi-Carmona, Didier Oustric, Bernard Pessegue
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1307:132-136
We have cloned the peripheral cannabinoid receptor, mCB2, from a mouse splenocyte cDNA library. The 3.7 kb sequence contains an open reading frame encoding a protein of 347 residues sharing 82% overall identity with the only other known peripheral re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a339058313b9d4428aef032212ef87
https://doi.org/10.1016/0167-4781(96)00047-4
https://doi.org/10.1016/0167-4781(96)00047-4
Autor:
Caroline Poinot-Chazel, Jean Marchand, Pierre Casellas, Xavier Canat, Bernard Calandra, Gérard Le Fur, Murielle Rinaldi-Carmona, Monsif Bouaboula, Bernard Bourrie
Publikováno v:
European Journal of Biochemistry. 237:704-711
Cannabinoids, known for their psychoactive effects, also possess immunomodulatory properties. The recent isolation and cloning of the G-protein-coupled peripheral cannabinoid receptor (CB2), mainly expressed in immune tissues, have provided molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac278ee67c6f9aa9a3bf508b1f98aeab
https://doi.org/10.1111/j.1432-1033.1996.0704p.x
https://doi.org/10.1111/j.1432-1033.1996.0704p.x
Autor:
Christiane Gueudet, Murielle Rinaldi-Carmona, Gérard Le Fur, Vincent Santucci, Philippe Soubrie
Publikováno v:
NeuroReport. 6:1421-1425
CB 1 receptors and their putative natural ligand anandamide, have been tentatively involved in the control of midbrain extrapyramidal function. Electrophysiological activity of dopamine neurones was measured after acute and repeated administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc5d265ad7e2ecde07d8ce77ea77816
https://doi.org/10.1097/00001756-199507100-00015
https://doi.org/10.1097/00001756-199507100-00015
Autor:
Michel Heaulme, Murielle Rinaldi-Carmona, Francis Barth, Philippe Soubrie, R. Alonso, Gérard Le Fur, Christian Congy, David Shire, Jean-Claude Breliere
Publikováno v:
Life Sciences. 56:1941-1947
SR141716A is a selective, potent and orally active antagonist of the brain cannabinoid receptor with a long duration of action. This compound shows high affinity for the central cannabinoid receptor (Ki = 2 nM), displays low affinity for the peripher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aa4e4e2c0ebb9124bbfd8178b26b7f
https://doi.org/10.1016/0024-3205(95)00174-5
https://doi.org/10.1016/0024-3205(95)00174-5