Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Muriel T. Davisson"'
Publikováno v:
BioTechniques, Vol 35, Iss 6, Pp 1170-1180 (2003)
The Ts65Dn mouse is a segmentally trisomic model for Down syndrome. Until now, Ts65Dn mice have been identified by the laborious methods of either chromosomal analysis of cultured peripheral lymphocytes or fluorescent in situ hybridization (FISH). We
Externí odkaz:
https://doaj.org/article/7b76cca8f70b448b9e9a6cb3033d5d60
Autor:
Muriel T. Davisson
Publikováno v:
BioTechniques, Vol 35, Iss 4, p 651 (2003)
Externí odkaz:
https://doaj.org/article/0d980d103f834758823eb68634092aec
Autor:
Muriel T Davisson, Roderick T Bronson, Abigail L D Tadenev, William W Motley, Arjun Krishnaswamy, Kevin L Seburn, Robert W Burgess
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29538 (2011)
Mutations in the gene encoding the immunoglobulin-superfamily member cell adhesion molecule contactin1 (CNTN1) cause lethal congenital myopathy in human patients and neurodevelopmental phenotypes in knockout mice. Whether the mutant mice provide an a
Externí odkaz:
https://doaj.org/article/a183325e00574c9e9215b7329df1512a
Publikováno v:
Neurobiology of Aging. 57:120-132
The Ts65Dn is a popular mouse model of Down syndrome (DS). It displays DS-relevant features of learning/memory deficits and age-related loss of functional markers in basal forebrain cholinergic neurons. Here we describe protein expression abnormaliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404da78d51992655d30865e1c48bf6ec
https://doi.org/10.1016/j.neurobiolaging.2017.05.002
https://doi.org/10.1016/j.neurobiolaging.2017.05.002
Autor:
Roderick T. Bronson, Ron Korstanje, Christina R. Caputo, Rosalinda A Doty, Susan A. Cook, Muriel T. Davisson, Jeffrey H. Miner
Publikováno v:
Kidney international
A spontaneous mutation termed bilateral wasting kidneys ( bwk ) was identified in a colony of NONcNZO recombinant inbred mice. These mice exhibit a rapid increase of urinary albumin at an early age associated with glomerulosclerosis, interstitial nep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482962353874fb0c394163914b334b44
https://doi.org/10.1038/ki.2013.493
https://doi.org/10.1038/ki.2013.493
Autor:
Roderick T. Bronson, Cheryl A. Kitt, Anny Wohn, Roger H. Reeves, Sangram S. Sisodia, N.G. Irving, Cecilia Schmidt, Muriel T. Davisson, Timothy H. Moran
Trisomy 21 or Down syndrome (DS) is the most frequent genetic cause of mental retardation, affecting one in 800 live born human beings. Mice with segmental trisomy 16 (Ts65Dn mice) are at dosage imbalance for genes corresponding to those on human chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8cb81f4c97de7b4a236b7455b5de4e
https://ora.ox.ac.uk/objects/uuid:25bd558e-7dd4-4e44-8810-6e3241c7ae32
https://ora.ox.ac.uk/objects/uuid:25bd558e-7dd4-4e44-8810-6e3241c7ae32
Publikováno v:
Journal of Proteome Research. 11:1251-1263
The Ts65Dn mouse model of Down syndrome (DS) is trisomic for orthologs of 88 of 161 classical protein coding genes present on human chromosome 21 (HSA21). Ts65Dn mice display learning and memory impairments and neuroanatomical, electrophysiological,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf228c92b20f8d0556563396b51b214
https://doi.org/10.1021/pr2011582
https://doi.org/10.1021/pr2011582
Autor:
Jiangping Zhang, Cong Tian, Casey Nava, Qing Yin Zheng, Fengchan Han, Heping Yu, Muriel T. Davisson, Cecilia Schmidt
Publikováno v:
International Journal of Experimental Pathology. 90:480-488
The Ts65Dn mouse shares many phenotypic characteristics of human Down syndrome. Here, we report that otitis media, characterized by effusion in the middle ear and hearing loss, was prevalent in Ts65Dn mice. Of the 53 Ts65Dn mice tested, 81.1% had hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460e401826d9ab6cf62e8ad0ed821c91
https://doi.org/10.1111/j.1365-2613.2009.00677.x
https://doi.org/10.1111/j.1365-2613.2009.00677.x
Autor:
Sujin Park, Yanling Zhang, Dan Goldowitz, Li Liu, Natsuko Jin, Muriel T. Davisson, Miriam H. Meisler, Clement Y. Chow, Roderick T. Bronson, Jason E. Duex, Jason L. Petersen, Lois S. Weisman, Sergey N. Zolov
Publikováno v:
The EMBO Journal. 27:3221-3234
The signalling lipid PI(3,5)P2 is generated on endosomes and regulates retrograde traffic to the trans-Golgi network. Physiological signals regulate rapid, transient changes in PI(3,5)P2 levels. Mutations that lower PI(3,5)P2 cause neurodegeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62436af7828515aa53e3a59499e73b68
https://doi.org/10.1038/emboj.2008.248
https://doi.org/10.1038/emboj.2008.248