Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Muriel Perron"'
Autor:
Juliette Bitard, Elodie-Kim Grellier, Sophie Lourdel, Helena Prior Filipe, Annaïg Hamon, François Fenaille, Florence Anne Castelli, Emeline Chu-Van, Jérôme E. Roger, Morgane Locker, Muriel Perron
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Glaucoma is a multifactorial neurodegenerative disease characterized by the progressive and irreversible degeneration of the optic nerve and retinal ganglion cells. Despite medical advances aiming at slowing degeneration, around 40% of treat
Externí odkaz:
https://doaj.org/article/5094564ec34949d59e846b3ed1d20852
Autor:
Béatrice Bocquet, Caroline Borday, Nejla Erkilic, Daria Mamaeva, Alicia Donval, Christel Masson, Karine Parain, Karolina Kaminska, Mathieu Quinodoz, Irene Perea-Romero, Gema Garcia-Garcia, Carla Jimenez-Medina, Hassan Boukhaddaoui, Arthur Coget, Nicolas Leboucq, Giacomo Calzetti, Stefano Gandolfi, Antonio Percesepe, Valeria Barili, Vera Uliana, Marco Delsante, Francesca Bozzetti, Hendrik P.N. Scholl, Marta Corton, Carmen Ayuso, Jose M. Millan, Carlo Rivolta, Isabelle Meunier, Muriel Perron, Vasiliki Kalatzis
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Retinitis pigmentosa (RP) is the most common inherited retinal disease (IRD) and is characterized by photoreceptor degeneration and progressive vision loss. We report 4 patients presenting with RP from 3 unrelated families with variants in TBC1D32, w
Externí odkaz:
https://doaj.org/article/95febfe0764a45129e5a016236db8fd5
Autor:
Rodrigo Meléndez García, Olivier Haccard, Albert Chesneau, Hemalatha Narassimprakash, Jérôme Roger, Muriel Perron, Kathrin Marheineke, Odile Bronchain
Publikováno v:
eLife, Vol 11 (2022)
In multicellular eukaryotic organisms, the initiation of DNA replication occurs asynchronously throughout S-phase according to a regulated replication timing program. Here, using Xenopus egg extracts, we showed that Yap (Yes-associated protein 1), a
Externí odkaz:
https://doaj.org/article/fcf16b0a76db442aa7209c9db2d822c1
Publikováno v:
Cells, Vol 11, Iss 18, p 2898 (2022)
Glycogen synthase kinase 3 (GSK3) is a key regulator of many cellular signaling processes and performs a wide range of biological functions in the nervous system. Due to its central role in numerous cellular processes involved in cell degeneration, a
Externí odkaz:
https://doaj.org/article/0d42f5133c9c4b23b602a90d1096189d
Autor:
Karine Parain, Sophie Lourdel, Alicia Donval, Albert Chesneau, Caroline Borday, Odile Bronchain, Morgane Locker, Muriel Perron
Publikováno v:
Cells, Vol 11, Iss 5, p 807 (2022)
Retinitis pigmentosa is an inherited retinal dystrophy that ultimately leads to blindness due to the progressive degeneration of rod photoreceptors and the subsequent non-cell autonomous death of cones. Rhodopsin is the most frequently mutated gene i
Externí odkaz:
https://doaj.org/article/34b9309b04e5467f96c918c127021bd6
Publikováno v:
Neural Development, Vol 12, Iss 1, Pp 1-15 (2017)
Abstract Background Amacrine interneurons that modulate synaptic plasticity between bipolar and ganglion cells constitute the most diverse cell type in the retina. Most are inhibitory neurons using either GABA or glycine as neurotransmitters. Althoug
Externí odkaz:
https://doaj.org/article/dfa85cf66cc04019934e852a9b065da5
Autor:
Annaïg Hamon, Diana García-García, Divya Ail, Juliette Bitard, Albert Chesneau, Deniz Dalkara, Morgane Locker, Jérôme E. Roger, Muriel Perron
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1712-1725.e6 (2019)
Summary: Contrasting with fish or amphibian, retinal regeneration from Müller glia is largely limited in mammals. In our quest toward the identification of molecular cues that may boost their stemness potential, we investigated the involvement of th
Externí odkaz:
https://doaj.org/article/f26f83ecc4714a97add9c99a0b53472d
Autor:
Caroline Borday, Karine Parain, Hong Thi Tran, Kris Vleminckx, Muriel Perron, Anne H Monsoro-Burq
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0193606 (2018)
Wnt proteins form a family of highly conserved secreted molecules that are critical mediators of cell-cell signaling during embryogenesis. Partial data on Wnt activity in different tissues and at different stages have been reported in frog embryos. O
Externí odkaz:
https://doaj.org/article/0bdf522920914900a251b4ac1a00b8b9
Autor:
Pauline Cabochette, Guillermo Vega-Lopez, Juliette Bitard, Karine Parain, Romain Chemouny, Christel Masson, Caroline Borday, Marie Hedderich, Kristine A Henningfeld, Morgane Locker, Odile Bronchain, Muriel Perron
Publikováno v:
eLife, Vol 4 (2015)
The adult frog retina retains a reservoir of active neural stem cells that contribute to continuous eye growth throughout life. We found that Yap, a downstream effector of the Hippo pathway, is specifically expressed in these stem cells. Yap knock-do
Externí odkaz:
https://doaj.org/article/d8299e71dae248db9470842400591f76
Autor:
Nicolas Mazurier, Karine Parain, Damien Parlier, Silvia Pretto, Johanna Hamdache, Philippe Vernier, Morgane Locker, Eric Bellefroid, Muriel Perron
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92113 (2014)
In contrast with the wealth of data involving bHLH and homeodomain transcription factors in retinal cell type determination, the molecular bases underlying neurotransmitter subtype specification is far less understood. Using both gain and loss of fun
Externí odkaz:
https://doaj.org/article/e79fa2241d394a538c19da9c9db111c3