Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Muriel Mazet"'
Autor:
Oriana Villafraz, Hélène Baudouin, Muriel Mazet, Hanna Kulyk, Jean-William Dupuy, Erika Pineda, Cyrille Botté, Daniel Ken Inaoka, Jean-Charles Portais, Frédéric Bringaud
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Unusual compartmentalization of metabolic pathways within organelles is one of the most enigmatic features of trypanosomatids. These unicellular eukaryotes are the only organisms that sequestered glycolysis inside peroxisomes (glycosomes), although t
Externí odkaz:
https://doaj.org/article/087ef0462d394133934b9d2367a4afc4
Autor:
Erika Pineda, Magali Thonnus, Muriel Mazet, Arnaud Mourier, Edern Cahoreau, Hanna Kulyk, Jean-William Dupuy, Marc Biran, Cyril Masante, Stefan Allmann, Loïc Rivière, Brice Rotureau, Jean-Charles Portais, Frédéric Bringaud
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007412 (2018)
The bloodstream forms of Trypanosoma brucei (BSF), the parasite protist causing sleeping sickness, primarily proliferate in the blood of their mammalian hosts. The skin and adipose tissues were recently identified as additional major sites for parasi
Externí odkaz:
https://doaj.org/article/62070a37071f4a23bf79a14ce1ae0583
Autor:
Yoann Millerioux, Muriel Mazet, Guillaume Bouyssou, Stefan Allmann, Tiila-Riikka Kiema, Eloïse Bertiaux, Laetitia Fouillen, Chandan Thapa, Marc Biran, Nicolas Plazolles, Franziska Dittrich-Domergue, Aline Crouzols, Rik K Wierenga, Brice Rotureau, Patrick Moreau, Frédéric Bringaud
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007116 (2018)
De novo biosynthesis of lipids is essential for Trypanosoma brucei, a protist responsible for the sleeping sickness. Here, we demonstrate that the ketogenic carbon sources, threonine, acetate and glucose, are precursors for both fatty acid and sterol
Externí odkaz:
https://doaj.org/article/9b8c7166f68b4ddd91c300754abc93b5
Autor:
Darren J Creek, Muriel Mazet, Fiona Achcar, Jana Anderson, Dong-Hyun Kim, Ruwida Kamour, Pauline Morand, Yoann Millerioux, Marc Biran, Eduard J Kerkhoven, Achuthanunni Chokkathukalam, Stefan K Weidt, Karl E V Burgess, Rainer Breitling, David G Watson, Frédéric Bringaud, Michael P Barrett
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004689 (2015)
Metabolomics coupled with heavy-atom isotope-labelled glucose has been used to probe the metabolic pathways active in cultured bloodstream form trypomastigotes of Trypanosoma brucei, a parasite responsible for human African trypanosomiasis. Glucose e
Externí odkaz:
https://doaj.org/article/6f5a415b91f34ce6b29b7e4fca138d7b
Autor:
Stefan Allmann, Muriel Mazet, Nicole Ziebart, Guillaume Bouyssou, Laetitia Fouillen, Jean-William Dupuy, Marc Bonneu, Patrick Moreau, Frédéric Bringaud, Michael Boshart
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114628 (2014)
Carbon storage is likely to enable adaptation of trypanosomes to nutritional challenges or bottlenecks during their stage development and migration in the tsetse. Lipid droplets are candidates for this function. This report shows that feeding of T. b
Externí odkaz:
https://doaj.org/article/5618831748784703bb0b711b6a31d90c
Autor:
Simone Pieretti, Jurgen R Haanstra, Muriel Mazet, Remo Perozzo, Christian Bergamini, Federica Prati, Romana Fato, Giorgio Lenaz, Giovanni Capranico, Reto Brun, Barbara M Bakker, Paul A M Michels, Leonardo Scapozza, Maria Laura Bolognesi, Andrea Cavalli
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e2012 (2013)
BACKGROUND AND METHODOLOGY: Recently, we reported on a new class of naphthoquinone derivatives showing a promising anti-trypanosomatid profile in cell-based experiments. The lead of this series (B6, 2-phenoxy-1,4-naphthoquinone) showed an ED(50) of 8
Externí odkaz:
https://doaj.org/article/4fcce31f431e43818aac51b0c0fcd7e6
Autor:
Muriel Mazet, Pauline Morand, Marc Biran, Guillaume Bouyssou, Pierrette Courtois, Sylvie Daulouède, Yoann Millerioux, Jean-Michel Franconi, Philippe Vincendeau, Patrick Moreau, Frédéric Bringaud
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2587 (2013)
BACKGROUND: The bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness, rely solely on glycolysis for ATP production. It is generally accepted that pyruvate is the major end-product excreted from glucose metabolism by the p
Externí odkaz:
https://doaj.org/article/d64332a40ccc4dbeb5a11d3150ce32eb
Autor:
Erika Pineda, Jean-Charles Portais, Cyrille Y. Botté, Hélène Baudouin, Jean-William Dupuy, Hanna Kulyk, Daniel Ken Inaoka, Oriana Villafraz, Frédéric Bringaud, Muriel Mazet
Publikováno v:
mBio
mBio, 2021, 12 (3), ⟨10.1128/mBio.00375-21⟩
mBio, 2021, 12 (3), ⟨10.1128/mBio.00375-21⟩
Glycosomes are peroxisome-related organelles of trypanosomatid parasites containing metabolic pathways usually present in the cytosol of other eukaryotes, such as glycolysis and biosynthesis of sugar nucleotides. UDP-glucose pyrophosphorylase (UGP),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9181f733a61d8936686afcb664c8fe24
https://hal.archives-ouvertes.fr/hal-03364995
https://hal.archives-ouvertes.fr/hal-03364995
Autor:
Muriel Mazet
Au cours de son existence chacun possède son propre chemin à parcourir. Parfois il nous arrive de le perdre, mais il nous est aussi possible de le retrouver afin de le poursuivre durant toute notre vie.Mais qu'est-ce que donner un sens à sa vie? L
Autor:
Daniel Ken Inaoka, Keisuke Fukuda, Emmanuel Oluwadare Balogun, Michael Boshart, Muriel Mazet, Yoann Millerioux, Kenji Hirayama, Kota Mochizuki, Frédéric Bringaud, Tomoo Shiba, Shigeharu Harada, Hana Kurasawa, Kiyoshi Kita
Publikováno v:
Biochimica biophysica acta (BBA)-Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2020, 1861 (11), pp.148283. ⟨10.1016/j.bbabio.2020.148283⟩
Biochimica et Biophysica Acta. Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2020, 1861 (11), pp.148283. ⟨10.1016/j.bbabio.2020.148283⟩
Biochimica et Biophysica Acta. Bioenergetics
Acetate:succinate CoA transferase (ASCT) is a mitochondrial enzyme that catalyzes the production of acetate and succinyl-CoA, which is coupled to ATP production with succinyl-CoA synthetase (SCS) in a process called the ASCT/SCS cycle. This cycle has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66d59bd4a132d226291e1fe78b57801
https://hal.archives-ouvertes.fr/hal-03009591/file/TbASCT-Manuscript-woTC-200609-2-pdf.pdf
https://hal.archives-ouvertes.fr/hal-03009591/file/TbASCT-Manuscript-woTC-200609-2-pdf.pdf