Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Muriel J. Caslake"'
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 9, Pp 2086-2095 (2007)
Isotopic tracer methods of determining triglyceride-rich lipoprotein (TRL) kinetics are costly, time-consuming, and labor-intensive. This study aimed to develop a simpler and cost-effective method of obtaining TRL kinetic data, based on the fact that
Externí odkaz:
https://doaj.org/article/c2b9c5e0f2dd44ebb6c2df568dddc311
Autor:
Martin Adiels, Chris Packard, Muriel J. Caslake, Philip Stewart, Aino Soro, Jukka Westerbacka, Bernt Wennberg, Sven-Olof Olofsson, Marja-Riitta Taskinen, Jan Borén
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 1, Pp 58-67 (2005)
The use of stable isotopes in conjunction with compartmental modeling analysis has greatly facilitated studies of the metabolism of the apolipoprotein B (apoB)-containing lipoproteins in humans. The aim of this study was to develop a multicompartment
Externí odkaz:
https://doaj.org/article/10684d1c450f45ea876b875d3903b048
Autor:
Hazel A. Ardern, G. Martin Benson, Keith E. Suckling, Muriel J. Caslake, James Shepherd, Chris J. Packard
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 12, Pp 2234-2243 (1999)
The St. Thomas' mixed hyperlipidemic (SMHL) rabbit (previously St. Thomas' Hospital rabbit) is a putative model of familial combined hyperlipidemia (FCH). When fed a low (0.08%) cholesterol diet, it exhibits elevations in both plasma cholesterol and
Externí odkaz:
https://doaj.org/article/82067a83eb6d4cc9adc6d138fc5a9a2d
Autor:
Chris J. Packard, Philip C. Calder, Christopher K. Armah, Bettina M. Kofler, Elizabeth A. Miles, J. Madden, Christine M. Williams, Allan Clark, Anne Marie Minihane, Muriel J. Caslake, John C. Mathers, Peter J. Curtis, Georg Lietz
Publikováno v:
The Journal of Nutrition. 146:516-523
BACKGROUND: Although many randomized controlled trials (RCTs) have examined the effects of the n-3 (ω-3) fatty acids eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) on blood pressure (BP) and vascular function, the major
Autor:
Kieren G. Hollingsworth, Ahmad Al-Mrabeh, Muriel J. Caslake, Benjamin S. Aribisala, Roy Taylor, S Steven, Leah Avery
Publikováno v:
Diabetes care. 41(6)
An error has been identified in the formula used to calculate VLDL1 production rate in the article cited above. This error does not affect the conclusions of the study …
Autor:
Jamie Robertson, Muriel J. Caslake, Duncan Porter, Iain B. McInnes, Naveed Sattar, Chris J. Packard, D McCarey
Publikováno v:
Annals of the rheumatic diseases. 76(11)
ObjectivesPatients with rheumatoid arthritis (RA) have reduced serum low-density lipoprotein cholesterol (LDL-c), which increases following therapeutic IL-6 blockade. We aimed to define the metabolic pathways underlying these lipid changes.MethodsIn
Publikováno v:
Sodi, R, Eastwood, J, Caslake, M, Packard, C J & Denby, L 2017, ' Relationship between circulating microRNA-30c with total-and LDL-cholesterol, their circulatory transportation and effect of statins ', Clinica Chimica Acta, vol. 466, pp. 13-19 . https://doi.org/10.1016/j.cca.2016.12.031
Background: Small non-coding microRNAs (miR) have important regulatory roles and are used as biomarkers of\ud disease. We investigated the relationship between lipoproteins and circulating miR-30c, evaluated how they are\ud transported in circulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c24bec539e8cd97aaeb3843713a5c6
https://eprints.gla.ac.uk/134644/1/134644.pdf
https://eprints.gla.ac.uk/134644/1/134644.pdf
Autor:
Dewan S. Alam, Martina Müller-Nurasyid, Pei Gao, Akinori Kimura, Danish Saleheen, Emanuele Di Angelantonio, Stefan Blankenberg, Taishi Sasaoka, Jean Ferrières, Børge G. Nordestgaard, Panos Deloukas, Abbas Dehghan, Eric Boerwinkle, Maria Uria-Nickelsen, Simon G. Thompson, Markus Perola, Chris J. Packard, Giovanni Veronesi, Dominique Arveiler, Dermot F. Reilly, Patricia B. Munroe, Stephen Burgess, Rajiv Chowdhury, Philippe Amouyel, J. Wouter Jukema, Alex Thompson, Francesco Gianfagna, Satu Männistö, Honghuang Lin, Nathan O. Stitziel, Heribert Schunkert, Naveed Sattar, Vladan Mijatovic, Abdulla Al Shafi Majumder, Nilesh J. Samani, Daniel F. Freitag, Stephen Kaptoge, Sekar Kathiresan, Stella Trompet, Peter Willeit, Jukka Kontto, John Danesh, Georg Ehret, Veikko Salomaa, Adam S. Butterworth, Joanna M. M. Howson, Ian Ford, Mathias Gorski, Kari Kuulasmaa, Yoshiji Yamada, Norihiro Kato, John M. Gregson, Frank Kee, Fumihiko Takeuchi, Praveen Surendran, James R Staley, Linda M. Polfus, Sune F. Nielsen, Anders Mälarstig, Thomas F. Vogt, Muriel J. Caslake
Publikováno v:
European Journal of Preventive Cardiology, 24(5), 492-504
Gregson, J M, Freitag, D F, Surendran, P, Stitziel, N O, Chowdhury, R, Burgess, S, Kaptoge, S, Gao, P, Staley, J R, Willeit, P, Nielsen, S F, Caslake, M, Trompet, S, Polfus, L M, Kuulasmaa, K, Kontto, J, Perola, M, Blankenberg, S, Veronesi, G, Gianfagna, F, Männistö, S, Kimura, A, Lin, H, Reilly, D F, Gorski, M, Mijatovic, V, Munroe, P B, Ehret, G B, Thompson, A, Uria-Nickelsen, M, Malarstig, A, Dehghan, A, Vogt, T F, Sasaoka, T, Takeuchi, F, Kato, N, Yamada, Y, Kee, F, Müller-Nurasyid, M, Ferrières, J, Arveiler, D, Amouyel, P, Salomaa, V, Boerwinkle, E, Thompson, S G, Ford, I, Wouter Jukema, J, Sattar, N, Packard, C J, Shafi Majumder, A A, Alam, D S, Deloukas, P, Schunkert, H, Samani, N J, Kathiresan, S, Nordestgaard, B G, Saleheen, D, Howson, J M, Di Angelantonio, E, Butterworth, A S & Danesh, J 2017, ' Genetic invalidation of Lp-PLA 2 as a therapeutic target : Large-scale study of five functional Lp-PLA 2-lowering alleles ', European Journal of Preventive Cardiology, vol. 24, no. 5, pp. 492-504 . https://doi.org/10.1177/2047487316682186
European journal of preventive cardiology, vol. 24, no. 5, pp. 492-504
European Journal of Preventive Cardiology, 24(5), 492-504. SAGE Publications Ltd
Gregson, J M, Freitag, D F, Surendran, P, Stitziel, N O, Chowdhury, R, Burgess, S, Stephen, K, Gao, P, Staley, J R, Willeit, P, Nielsen, S F, Caslake, M, Trompet, S, Polfus, L M, Kuulasmaa, K, Kontto, J, Perola, M, Blankenberg, S, Veronesi, G, Gianfagna, F, Mannisto, S, Kimura, A, Lin, H, Reilly, D F, Gorski, M, Mijatovic, V, CKDGen consortium, Munroe, P B, Ehret, G B, International Consortium for Blood Pressure, Thompson, A, Uria-Nickelsen, M, Malarstig, A, Dehghan, A, CHARGE inflammation working group, Vogt, T F, Sasaoka, T, Takeuchi, F, Kato, N, Yamada, Y, Kee, F, Muller-Nurasyid, M, Ferrieres, J, Arveiler, D, Amouyel, P, Salomaa, V, Boerwinkle, E, Thompson, S G, Ford, I, Jukema, J W, Sattar, N, Packard, C J, Majumder, A A S, Alam, D S, Deloukas, P, Schunkert, H, Samani, N J, Kathiresan, S, MICAD Exome consortium, Nordestgaard, B G, Saleheen, D, Howson, J M M, Di Angelantonio, E, Butterworth, A S, Danesh, J, EPIC-CVD consortium & CHD Exome+ consortium 2017, ' Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles ', European Journal of Preventive Cardiology, vol. 24, no. 5, pp. 492-504 . https://doi.org/10.1177/2047487316682186
Gregson, J M, Freitag, D F, Surendran, P, Stitziel, N O, Chowdhury, R, Burgess, S, Kaptoge, S, Gao, P, Staley, J R, Willeit, P, Nielsen, S F, Caslake, M, Trompet, S, Polfus, L M, Kuulasmaa, K, Kontto, J, Perola, M, Blankenberg, S, Veronesi, G, Gianfagna, F, Männistö, S, Kimura, A, Lin, H, Reilly, D F, Gorski, M, Mijatovic, V, Munroe, P B, Ehret, G B, Thompson, A, Uria-Nickelsen, M, Malarstig, A, Dehghan, A, Vogt, T F, Sasaoka, T, Takeuchi, F, Kato, N, Yamada, Y, Kee, F, Müller-Nurasyid, M, Ferrières, J, Arveiler, D, Amouyel, P, Salomaa, V, Boerwinkle, E, Thompson, S G, Ford, I, Wouter Jukema, J, Sattar, N, Packard, C J, Shafi Majumder, A A, Alam, D S, Deloukas, P, Schunkert, H, Samani, N J, Kathiresan, S, Nordestgaard, B G, Saleheen, D, Howson, J M, Di Angelantonio, E, Butterworth, A S & Danesh, J 2017, ' Genetic invalidation of Lp-PLA 2 as a therapeutic target : Large-scale study of five functional Lp-PLA 2-lowering alleles ', European Journal of Preventive Cardiology, vol. 24, no. 5, pp. 492-504 . https://doi.org/10.1177/2047487316682186
European journal of preventive cardiology, vol. 24, no. 5, pp. 492-504
European Journal of Preventive Cardiology, 24(5), 492-504. SAGE Publications Ltd
Gregson, J M, Freitag, D F, Surendran, P, Stitziel, N O, Chowdhury, R, Burgess, S, Stephen, K, Gao, P, Staley, J R, Willeit, P, Nielsen, S F, Caslake, M, Trompet, S, Polfus, L M, Kuulasmaa, K, Kontto, J, Perola, M, Blankenberg, S, Veronesi, G, Gianfagna, F, Mannisto, S, Kimura, A, Lin, H, Reilly, D F, Gorski, M, Mijatovic, V, CKDGen consortium, Munroe, P B, Ehret, G B, International Consortium for Blood Pressure, Thompson, A, Uria-Nickelsen, M, Malarstig, A, Dehghan, A, CHARGE inflammation working group, Vogt, T F, Sasaoka, T, Takeuchi, F, Kato, N, Yamada, Y, Kee, F, Muller-Nurasyid, M, Ferrieres, J, Arveiler, D, Amouyel, P, Salomaa, V, Boerwinkle, E, Thompson, S G, Ford, I, Jukema, J W, Sattar, N, Packard, C J, Majumder, A A S, Alam, D S, Deloukas, P, Schunkert, H, Samani, N J, Kathiresan, S, MICAD Exome consortium, Nordestgaard, B G, Saleheen, D, Howson, J M M, Di Angelantonio, E, Butterworth, A S, Danesh, J, EPIC-CVD consortium & CHD Exome+ consortium 2017, ' Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles ', European Journal of Preventive Cardiology, vol. 24, no. 5, pp. 492-504 . https://doi.org/10.1177/2047487316682186
Aims Darapladib, a potent inhibitor of lipoprotein-associated phospholipase A javax.xml.bind.JAXBElement@3ed2b341 (Lp-PLA javax.xml.bind.JAXBElement@3d94c871 ), has not reduced risk of cardiovascular disease outcomes in recent randomized trials. We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b2ff2015d30a1017632842598090d2
http://hdl.handle.net/10044/1/54554
http://hdl.handle.net/10044/1/54554
Autor:
Christopher J. Packard, Philip J. Stewart, Johan Björkegren, Muriel J. Caslake, James Shepherd, Fredrik Karpe, Dorothy Bedford, L Foster, Anders Hamsten
Publikováno v:
Scopus-Elsevier
Journal of Lipid Research, Vol 37, Iss 1, Pp 76-86 (1996)
Journal of Lipid Research, Vol 37, Iss 1, Pp 76-86 (1996)
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5068698692187ee55f74a6f6e3e0e9c
https://ora.ox.ac.uk/objects/uuid:62446e3d-edd6-4bb0-95a5-8b166c4dc430
https://ora.ox.ac.uk/objects/uuid:62446e3d-edd6-4bb0-95a5-8b166c4dc430
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 462
Circulating miR-30c has been linked to various aspects of cholesterol homeostasis. The aim of this study was to determine the association of circulating miR-30c with the atherogenic lipoprotein subfractions. Samples from subjects who were given place