Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Muriel Gondry"'
Autor:
Fabien Le Chevalier, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, Pascal Belin
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CD
Externí odkaz:
https://doaj.org/article/f25dc7239b8a4460a3d5f4a96e21e08c
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Cyclodipeptide synthases (CDPSs) form various cyclodipeptides from two aminoacyl tRNAs via a stepwise mechanism with the formation of a dipeptidyl enzyme intermediate. As a final step of the catalytic reaction, the dipeptidyl group undergoes
Externí odkaz:
https://doaj.org/article/67204e16422a4345b9f2793575e3a217
Autor:
Muriel Gondry, Isabelle B. Jacques, Robert Thai, Morgan Babin, Nicolas Canu, Jérôme Seguin, Pascal Belin, Jean-Luc Pernodet, Mireille Moutiez
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Cyclodipeptide synthases (CDPSs) use as substrates two amino acids activated as aminoacyl-tRNAs to synthesize cyclodipeptides in secondary metabolites biosynthetic pathways. Since the first description of a CDPS in 2002, the number of putative CDPSs
Externí odkaz:
https://doaj.org/article/38fc13c19ddf4b8dbba2bb0e59d6d428
Autor:
Carine Tellier, Robin Vinck, Robert Thai, Morgan Babin, Nicolas Canu, Mireille Moutiez, Olivier Cinquin, Jean-Christophe Cintrat, Jérôme Seguin, Inès Ajel, Muriel Gondry, Pascal Belin
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (20), ⟨10.1093/nar/gkaa903⟩
Nucleic Acids Research, 2020, 48 (20), ⟨10.1093/nar/gkaa903⟩
Cyclodipeptide synthases (CDPSs) use two aminoacyl-tRNAs (AA-tRNAs) to catalyse cyclodipeptide formation in a ping-pong mechanism. Despite intense studies of these enzymes in past years, the tRNA regions of the two substrates required for CDPS activi
Autor:
Nicolas Canu, Muriel Gondry, Isabelle Correia, Pascal Belin, Robert Thai, Olivier Lequin, Isabelle Jacques, Pavlina Dubois, Steven G. DuBois, Fabien Le Chevalier, Mireille Moutiez
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Prenylated indole diketopiperazine (DKP) alkaloids are important bioactive molecules or their precursors. In the context of synthetic biology, efficient means for their biological production would increase their chemical diversification and the disco
Publikováno v:
Biochemistry
Biochemistry, 2021, 60 (1), pp.64-76. ⟨10.1021/acs.biochem.0c00761⟩
Biochemistry, American Chemical Society, 2021, 60 (1), pp.64-76. ⟨10.1021/acs.biochem.0c00761⟩
Biochemistry, 2021, 60 (1), pp.64-76. ⟨10.1021/acs.biochem.0c00761⟩
Biochemistry, American Chemical Society, 2021, 60 (1), pp.64-76. ⟨10.1021/acs.biochem.0c00761⟩
International audience; Cyclodipeptide synthases (CDPSs) perform nonribosomal protein synthesis using two aminoacyl-tRNA substrates to produce cyclodipeptides. There is no available structural detail on the CDPS:tRNA interaction to date. Using AlbC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536421fea2c3f2cc0198ea4cdb051ca6
https://hal.science/hal-03084339
https://hal.science/hal-03084339
Autor:
Olivier Lequin, Nicolas Canu, Muriel Gondry, Pascal Belin, Isabelle Correia, Mireille Moutiez, Morgan Babin, Lucrèce Matheron, Fabien Le Chevalier
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, 2020, 19 (1), pp.178. ⟨10.1186/s12934-020-01432-y⟩
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Microbial Cell Factories, 2020, 19 (1), pp.178. ⟨10.1186/s12934-020-01432-y⟩
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-depen
Publikováno v:
Natural Product Reports
Natural Product Reports, Royal Society of Chemistry, 2020, ⟨10.1039/c9np00036d⟩
Natural Product Reports, 2020, ⟨10.1039/c9np00036d⟩
Natural Product Reports, Royal Society of Chemistry, 2020, ⟨10.1039/c9np00036d⟩
Natural Product Reports, 2020, ⟨10.1039/c9np00036d⟩
Covering: Up to mid-2019 Cyclodipeptide synthases (CDPSs) catalyse the formation of cyclodipeptides using aminoacylated-tRNA as substrates. The recent characterization of large sets of CDPSs has revealed that they can produce highly diverse products,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e47fd6854eb455c1f591b7c2be86a8
https://hal.archives-ouvertes.fr/hal-02415937
https://hal.archives-ouvertes.fr/hal-02415937
Autor:
Pavlina Dubois, Robert Thai, Mireille Moutiez, Steven G. DuBois, Muriel Gondry, Pascal Belin, Isabelle Correia, Nicolas Canu, Fabien Le Chevalier, Olivier Lequin, Isabelle Jacques
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-2 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, 2019, 9 (1), pp.15009. ⟨10.1038/s41598-019-51404-5⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-2 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches
Autor:
Jérôme Seguin, Emmanuel Favry, Isabelle Correia, Jean-Luc Pernodet, Sylvie Lautru, Jerzy Witwinowski, Laëtitia Caraty, Mireille Moutiez, Matthieu Coupet, Corinne Saulnier, Olivier Lequin, Muriel Gondry, Pascal Belin, Emmanuelle Darbon, Antonio C. Ruzzini
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.20226. ⟨10.1038/s41598-019-56747-7⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-56747-7⟩
Scientific Reports, 2019, 9 (1), pp.20226. ⟨10.1038/s41598-019-56747-7⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.20226. ⟨10.1038/s41598-019-56747-7⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-56747-7⟩
Scientific Reports, 2019, 9 (1), pp.20226. ⟨10.1038/s41598-019-56747-7⟩
The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737ea58699d6e1abfd1d6af06e9a0677
https://hal.archives-ouvertes.fr/hal-02431235/document
https://hal.archives-ouvertes.fr/hal-02431235/document