A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.

Autor: Augusto DG; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA.; Department of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, NC, USA.; Programa de Pós-Graduação em Genética, Universidade Federal do Paraná, Curitiba, Brazil., Murdolo LD; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Chatzileontiadou DSM; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Sabatino JJ Jr; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Yusufali T; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Peyser ND; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Butcher X; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Kizer K; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Guthrie K; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Murray VW; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Pae V; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Sarvadhavabhatla S; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Beltran F; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Gill GS; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Lynch KL; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Yun C; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Maguire CT; Clinical and Translational Science Institute, University of Utah, Salt Lake City, UT, USA., Peluso MJ; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Hoh R; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Henrich TJ; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Deeks SG; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Davidson M; Department of Medicine, University of California, San Francisco, CA, USA., Lu S; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Goldberg SA; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Kelly JD; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.; F.I. Proctor Foundation, University of California, San Francisco, CA, USA., Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Vierra-Green CA; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Spellman SR; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Langton DJ; ExplantLab, Newcastle-upon-Tyne, UK., Dewar-Oldis MJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Smith C; QIMR Berghofer Centre for Immunotherapy and Vaccine Development Brisbane, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Barnard PJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Lee S; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Marcus GM; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Olgin JE; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Pletcher MJ; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.; Division of General Internal Medicine, University of California, San Francisco, CA, USA., Maiers M; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Gras S; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Hollenbach JA; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.

Publikováno v: Nature [Nature] 2023 Aug; Vol. 620 (7972), pp. 128-136. Date of Electronic Publication: 2023 Jul 19.

A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.

Autor: Augusto DG; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Programa de Pós-Graduação em Genética, Universidade Federal do Paraná, Curitiba, Brazil.; Department of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, NC, USA., Yusufali T; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Sabatino JJ Jr; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Peyser ND; Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Murdolo LD; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia., Butcher X; Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Murray V; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Pae V; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Sarvadhavabhatla S; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Beltran F; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Gill G; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Lynch K; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA., Yun C; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA., Maguire C; University of Utah, Clinical and Translational Science Institute, Salt Lake City, UT., Peluso MJ; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Hoh R; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Henrich TJ; Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Deeks SG; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Davidson M; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Lu S; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA., Goldberg SA; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA., Kelly JD; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.; F.I. Proctor Foundation, University of California San Francisco, San Francisco, CA, USA., Martin JN; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA., Viera-Green CA; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, Minnesota., Spellman SR; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, Minnesota., Langton DJ; ExplantLab, The Biosphere, Newcastle Helix, Newcastle-upon-Tyne, UK., Lee S; Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Marcus GM; Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Olgin JE; Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Pletcher MJ; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.; Division of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA., Gras S; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia., Maiers M; National Marrow Donor Program, Minneapolis, MN., Hollenbach JA; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2022 Oct 12. Date of Electronic Publication: 2022 Oct 12.