A second space age spanning omics, platforms and medicine across orbits.

Autor: Mason CE; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA. chm2042@med.cornell.edu.; The WorldQuant Initiative for Quantitative Prediction, New York, NY, USA. chm2042@med.cornell.edu., Green J; Metavisionairies, Oxford, UK., Adamopoulos KI; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Biomedical Engineering Laboratory, School of Electrical and Computer Engineering, National University of Athens, Athens, Greece., Afshin EE; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Baechle JJ; Buck Artificial Intelligence Platform, Buck Institute for Research on Aging, Novato, CA, USA., Basner M; Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bailey SM; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA., Bielski L; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Borg J; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.; Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Msida, Malta., Borg J; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.; Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Msida, Malta., Broddrick JT; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Burke M; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA.; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, USA., Caicedo A; Instituto de Investigaciones en Biomedicina iBioMed, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Escuela de Medicina, Colegio de Ciencias de la Salud COCSA, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Sistemas Médicos SIME, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Mito-Act Research Consortium, Quito, Ecuador., Castañeda V; Faculty of Medicine, Universidad de los Andes, Santiago, Chile.; IMPACT, Center of Interventional Medicine for Precision and Advanced Cellular Therapy, Santiago, Chile.; Molecular Biology and Bioinformatics Lab, Program in Molecular Biology and Bioinformatics, Center for Biomedical Research and Innovation (CIIB), Universidad de los Andes, Santiago, Chile., Chatterjee S; Southwest Research Institute, Boulder, CO, USA., Chin CR; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Church G; Harvard Medical School, Boston, MA, USA., Costes SV; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., De Vlaminck I; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Desai RI; Integrative Neurochemistry Laboratory, Behavioral Biology Program, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA., Dhir R; Seed Health, Venice, CA, USA.; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland., Diaz JE; Data Science Institute, School of Business, Universidad San Francisco de Quito USFQ, Quito, Ecuador., Etlin SM; Department of Astrobiology, Cornell University, New York, NY, USA., Feinstein Z; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Furman D; Buck Institute for Research on Aging, Novato, CA, USA.; Stanford 1000 Immunomes Project, Stanford University School of Medicine, Stanford, CA, USA.; Institute for Research in Translational Medicine, Universidad Austral, CONICET, Pilar, Argentina., Garcia-Medina JS; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Garrett-Bakelman F; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Giacomello S; Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden., Gupta A; ANYg Labs, San Diego, CA, USA., Hassanin A; Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Houerbi N; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Irby I; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Javorsky E; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Future of Life Institute, Campbell, CA, USA., Jirak P; Paracelsus Medical University, Salzburg, Austria.; Department of Internal Medicine, Hospital Gmünd, Lower Austria, Austria., Jones CW; Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Kamal KY; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA.; Department of Kinesiology, Iowa State University, Ames, USA., Kangas BD; Behavioral Biology Program, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA., Karouia F; Blue Marble Institute of Science, Exobiology Branch NASA Ames Research Center, Moffett Field, CA, USA.; Space Research Within Reach, San Francisco, CA, USA.; Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.; BioServe Space Technologies, Smead Aerospace Engineering Science Department, University of Colorado Boulder, Boulder, CO, USA., Kim J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Kim JH; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Kleinman AS; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Lam T; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA., Lawler JM; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Lee JA; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Limoli CL; Department of Radiation Oncology, University of California, Irvine, CA, USA., Lucaci A; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., MacKay M; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., McDonald JT; Department of Radiation Medicine, Georgetown University School of Medicine, Washington, D.C., USA., Melnick AM; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Meydan C; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Mieczkowski J; International Research Agenda 3P-Medicine Laboratory, Medical University of Gdansk, Gdansk, Poland., Muratani M; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan., Najjar D; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Othman MA; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Overbey EG; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; BioAstra, New York, NY, USA., Paar V; Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University, Salzburg, Austria., Park J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Paul AM; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, USA., Perdyan A; International Research Agenda 3P-Medicine Laboratory, Medical University of Gdansk, Gdansk, Poland.; Department of Biology, Stanford University, Stanford, CA, USA., Proszynski J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Reynolds RJ; University of Texas Medical Branch, Galveston, TX, USA.; KBR, Inc., Houston, TX, USA., Ronca AE; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Wake Forest Medical School, Dept of Obstetrics and Gynecology, Winston-Salem, NC, USA., Rubins K; NASA Johnson Space Center, Houston, TX, USA., Ryon KA; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Sanders LM; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Glowe PS; BioAstra, Los Angeles, CA, USA., Shevde Y; Ursa Biotechnology Corporation, Ursa Bio, New York, NY, USA., Schmidt MA; Sovaris Aerospace, Boulder, CO, USA., Scott RT; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Shirah B; Department of Neuroscience, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia., Sienkiewicz K; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Sierra MA; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Siew K; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Theriot CA; University of Texas Medical Branch, Galveston, TX, USA., Tierney BT; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Venkateswaran K; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA., Hirschberg JW; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Walsh SB; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Walter C; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Winer DA; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Division of Cellular and Molecular Biology, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Yu M; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA., Zea L; Smead Aerospace Engineering Sciences Department, University of Colorado Boulder, Boulder, CO, USA.; Jaguar Space, LLC, Erie, CO, USA., Mateus J; Space Exploration Technologies Corporation (SpaceX), Hawthorne, CA, USA., Beheshti A; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA. abehesht@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. abehesht@broadinstitute.org.

Publikováno v: Nature [Nature] 2024 Aug; Vol. 632 (8027), pp. 995-1008. Date of Electronic Publication: 2024 Jun 11.

Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel.

Autor: Okamura Y; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; College of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, 305-8575, Japan., Gochi K; Department of Cellular Physiological Chemistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, 113-8549, Japan.; Department of Rehabilitation for Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities, Saitama, 359-8555, Japan., Ishikawa T; Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, 230-0045, Japan., Hayashi T; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Fuseya S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, 305-8565, Japan., Suzuki R; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Kanai M; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Inoue Y; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Murakami Y; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan., Sadaki S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Ph.D. Program in Humanics, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan., Jeon H; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Hayama M; Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, 230-0045, Japan., Ishii H; Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, 230-0045, Japan., Tsunakawa Y; Department of Rehabilitation for Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities, Saitama, 359-8555, Japan., Ochi H; Department of Rehabilitation for Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities, Saitama, 359-8555, Japan., Sato S; Center for Innovative Cancer Treatment, Institute of Science Tokyo, Tokyo, 113-8510, Japan., Hamada M; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan., Abe C; Department of Physiology, Gifu University Graduate School of Medicine, Gifu, 501-1194, Japan., Morita H; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan.; Department of Nutrition Management, Tokai Gakuin University, Gifu, 504-8511, Japan., Okada R; Space Environment Utilization Center, Human Spaceflight Technology Directorate, JAXA, Tsukuba, Ibaraki, 305-8505, Japan., Shiba D; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan.; Space Environment Utilization Center, Human Spaceflight Technology Directorate, JAXA, Tsukuba, Ibaraki, 305-8505, Japan., Muratani M; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan.; Department of Genome Biology, Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan., Shinohara M; Department of Rehabilitation for Movement Functions, Research Institute, National Rehabilitation Center for Persons with Disabilities, Saitama, 359-8555, Japan.; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan., Akiyama T; Laboratory for Immune Homeostasis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, 230-0045, Japan.; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan., Kudo T; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. t-kudo@md.tsukuba.ac.jp.; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan. t-kudo@md.tsukuba.ac.jp., Takahashi S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. satoruta@md.tsukuba.ac.jp.; Mouse Epigenetics Project, ISS/Kibo Experiment, Japan Aerospace Exploration, Tsukuba, Japan. satoruta@md.tsukuba.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2024 Nov 20; Vol. 14 (1), pp. 28774. Date of Electronic Publication: 2024 Nov 20.

Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation.

Autor: Hayashi T; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Sadaki S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.; PhD Program in Humanics, School of Integrative and Global Majors, University of Tsukuba, Ibaraki 305-8575, Japan., Tsuji R; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.; PhD Program in Humanics, School of Integrative and Global Majors, University of Tsukuba, Ibaraki 305-8575, Japan., Okada R; JEM Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency (JAXA), Ibaraki 305-8505, Japan., Fuseya S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Ibaraki 305-8565, Japan., Kanai M; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Nakamura A; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.; College of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Ibaraki 305-8575, Japan., Okamura Y; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.; College of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Ibaraki 305-8575, Japan., Muratani M; Department of Genome Biology, Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Wenchao G; Department of Diagnostic and Interventional Radiology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Sugasawa T; Laboratory of Clinical Examination and Sports Medicine, Department of Clinical Medicine, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Laboratory Animal Science, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Warabi E; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Kudo T; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Takahashi S; Laboratory Animal Resource Center in Transborder Medical Research Center, and Department of Anatomy and Embryology, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan., Fujita R; Division of Regenerative Medicine, Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan.

Publikováno v: Stem cells (Dayton, Ohio) [Stem Cells] 2024 Sep 10; Vol. 42 (9), pp. 830-847.

Protective alleles and precision healthcare in crewed spaceflight.

Autor: Rutter LA; Transborder Medical Research Center, University of Tsukuba, Ibaraki, 305-8575, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., MacKay MJ; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA., Cope H; School of Medicine, University of Nottingham, Nottingham, DE22 3DT, UK., Szewczyk NJ; School of Medicine, University of Nottingham, Nottingham, DE22 3DT, UK.; Ohio Musculoskeletal and Neurological Institute (OMNI), Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA., Kim J; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA., Overbey E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA., Tierney BT; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA., Muratani M; Transborder Medical Research Center, University of Tsukuba, Ibaraki, 305-8575, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan., Lamm B; Colossal Biosciences, 1401 Lavaca St, Unit #155 Austin, Austin, TX, 78701, USA., Bezdan D; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen (NCCT), University of Tübingen, Tübingen, Germany.; Yuri GmbH, Meckenbeuren, Germany., Paul AM; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, 32114, USA., Schmidt MA; Sovaris Aerospace, Boulder, CO, 80302, USA. mschmidtphd@patternanalysis.org.; Advanced Pattern Analysis & Human Performance Group, Boulder, CO, 80302, USA. mschmidtphd@patternanalysis.org., Church GM; GC Therapeutics Inc, Cambridge, MA, 02139, USA. gc@hms.harvard.edu.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA. gc@hms.harvard.edu.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, 02115, USA. gc@hms.harvard.edu., Giacomello S; SciLifeLab, KTH Royal Institute of Technology, Stockholm, 17165, Sweden. stefania.giacomello@scilifelab.se., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA. chm2042@med.cornell.edu.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, 02115, USA. chm2042@med.cornell.edu.; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 22; Vol. 15 (1), pp. 6158. Date of Electronic Publication: 2024 Jul 22.

Astronaut omics and the impact of space on the human body at scale.

Autor: Rutter LA; Transborder Medical Research Center, University of Tsukuba, 305-8575, Tsukuba, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, 305-8575, Tsukuba, Japan.; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Cope H; School of Medicine, University of Nottingham, Derby, DE22 3DT, UK., MacKay MJ; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA., Herranz R; Centro de Investigaciones Biológicas 'Margarita Salas' (CSIC), Ramiro de Maeztu 9, Madrid, 28040, Spain., Das S; Department of Biochemistry, Atal Bihari Vajpayee Institute of Medical Sciences & Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India., Ponomarev SA; Department of Immunology and Microbiology, Institute for the Biomedical Problems, Russian Academy of Sciences, 123007, Moscow, Russia., Costes SV; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, USA., Paul AM; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, 32114, USA., Barker R; Department of Botany, University of Wisconsin-Madison, Madison, WI, 53706, USA., Taylor DM; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Bezdan D; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, 72076, Germany.; NGS Competence Center Tübingen (NCCT), University of Tübingen, Tübingen, 72076, Germany.; yuri GmbH, Meckenbeuren, 88074, Germany., Szewczyk NJ; School of Medicine, University of Nottingham, Derby, DE22 3DT, UK.; Ohio Musculoskeletal and Neurological Institute (OMNI), Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA., Muratani M; Transborder Medical Research Center, University of Tsukuba, 305-8575, Tsukuba, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, 305-8575, Tsukuba, Japan., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA. chm2042@med.cornell.edu.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu., Giacomello S; SciLifeLab, KTH Royal Institute of Technology, Stockholm, 17165, Sweden. stefania.giacomello@scilifelab.se.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 11; Vol. 15 (1), pp. 4952. Date of Electronic Publication: 2024 Jun 11.