Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Murat S Durakoglugil"'
Autor:
Catherine R. Wasser, Gordon C. Werthmann, Eric M. Hall, Kristina Kuhbandner, Connie H. Wong, Murat S. Durakoglugil, Joachim Herz
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-24 (2023)
Abstract Background ApoE4, the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), sequesters a pro-synaptogenic Reelin receptor, Apoer2, in the endosomal compartment and prevents its normal recycling. In the adult brain,
Externí odkaz:
https://doaj.org/article/7a77c3c7cc5e441990b9400990388085
Autor:
Theresa Pohlkamp, Xunde Xian, Connie H Wong, Murat S Durakoglugil, Gordon Chandler Werthmann, Takaomi C Saido, Bret M Evers, Charles L White III, Jade Connor, Robert E Hammer, Joachim Herz
Publikováno v:
eLife, Vol 10 (2021)
Apolipoprotein E4 (ApoE4) is the most important and prevalent risk factor for late-onset Alzheimer’s disease (AD). The isoelectric point of ApoE4 matches the pH of the early endosome (EE), causing its delayed dissociation from ApoE receptors and he
Externí odkaz:
https://doaj.org/article/3091328afffb402889ce2628db3b91a1
Autor:
Xunde Xian, Theresa Pohlkamp, Murat S Durakoglugil, Connie H Wong, Jürgen K Beck, Courtney Lane-Donovan, Florian Plattner, Joachim Herz
Publikováno v:
eLife, Vol 7 (2018)
ApoE4 genotype is the most prevalent and also clinically most important risk factor for late-onset Alzheimer’s disease (AD). Available evidence suggests that the root cause for this increased risk is a trafficking defect at the level of the early e
Externí odkaz:
https://doaj.org/article/56ac5602a3b543ba97edca746b7d6a70
Autor:
Bret M. Evers, Robert E. Hammer, Xunde Xian, Murat S. Durakoglugil, Theresa Pohlkamp, Gordon Chandler Werthmann, Charles L. White, Connie H Wong, Joachim Herz, Jade Connor, Takaomi C. Saido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55c8d383b446156584cf3109354d87f6
https://doi.org/10.7554/elife.72034.sa2
https://doi.org/10.7554/elife.72034.sa2
Autor:
Robert E. Hammer, Bret M. Evers, Theresa Pohlkamp, Gordon Chandler Werthmann, Charles L. White, Connie H Wong, Jade Connor, Takaomi C. Saido, Xunde Xian, Joachim Herz, Murat S. Durakoglugil
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Apolipoprotein E4 (ApoE4) is the most important and prevalent risk factor for late-onset Alzheimer’s disease (AD). The isoelectric point of ApoE4 matches the pH of the early endosome (EE), causing its delayed dissociation from ApoE receptors and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f65e4560a463a9031b0abb07240bdeb
https://doi.org/10.1101/2021.03.22.436385
https://doi.org/10.1101/2021.03.22.436385
Autor:
Lea Naestle, Joachim Herz, Xunde Xian, Catherine R. Wasser, Theresa Pohlkamp, Connie H Wong, Courtney Lane-Donovan, Murat S. Durakoglugil, Katja E. Fritschle
Alzheimer’s disease (AD) is a progressive neurodegenerative disease marked by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles. Aβ oligomers cause synaptic dysfunction early in AD by enhancing long-term depression (LTD, a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf59c17c1e5382d546a141c35ec94bd
https://mediatum.ub.tum.de/doc/1640036/document.pdf
https://mediatum.ub.tum.de/doc/1640036/document.pdf
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction Currently, there is no cure for Alzheimer's disease (AD), and it is widely accepted that AD is a complex disease with multiple approaches necessary to prevent and treat the disease. Methods Using amyloid biomarkers in human cerebrospinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd8878c6995f90b648813cfe7dfe68d
https://pubmed.ncbi.nlm.nih.gov/31921961
https://pubmed.ncbi.nlm.nih.gov/31921961
Autor:
Xunde Xian, Florian Plattner, Jürgen K Beck, Courtney Lane-Donovan, Connie H Wong, Theresa Pohlkamp, Murat S. Durakoglugil, Joachim Herz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98b7bf6f7108ccbee9a2c03a8c27012
https://doi.org/10.7554/elife.40048.024
https://doi.org/10.7554/elife.40048.024
Autor:
Courtney Lane-Donovan, Jürgen K Beck, Murat S. Durakoglugil, Florian Plattner, Joachim Herz, Xunde Xian, Connie H Wong, Theresa Pohlkamp
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
ApoE4 genotype is the most prevalent and also clinically most important risk factor for late-onset Alzheimer’s disease (AD). Available evidence suggests that the root cause for this increased risk is a trafficking defect at the level of the early e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8263d91495485cafb368af8dd1ad18f
https://pubmed.ncbi.nlm.nih.gov/30375977
https://pubmed.ncbi.nlm.nih.gov/30375977
Autor:
Catherine R. Wasser, Joachim Herz, Courtney Lane-Donovan, Wen Mai Wong, Shan Jiang, Xunde Xian, Murat S. Durakoglugil
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(39)
Alzheimer's disease (AD) is the most common form of dementia in individuals over the age of 65 years. The most prevalent genetic risk factor for AD is the ε4 allele of apolipoprotein E (ApoE4), and novel AD treatments that target ApoE are being cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ff4335f10ef347b779885192900890
https://pubmed.ncbi.nlm.nih.gov/27683909
https://pubmed.ncbi.nlm.nih.gov/27683909