Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Murat K, Saparbaev"'
Publikováno v:
PeerJ, Vol 11, p e16671 (2023)
Background Francis Crick’s central dogma provides a residue-by-residue mechanistic explanation of the flow of genetic information in living systems. However, this principle may not be sufficient for explaining how random mutations cause continuous
Externí odkaz:
https://doaj.org/article/ebd6f588827144bd958b31e8bffa5f1b
Autor:
Anna V Yudkina, Nikita A Bulgakov, Daria V Kim, Svetlana V Baranova, Alexander A Ishchenko, Murat K Saparbaev, Vladimir V Koval, Dmitry O Zharkov
Publikováno v:
Nucleic Acids Research.
Apurinic/apyrimidinic (AP) sites are abundant DNA lesions arising from spontaneous hydrolysis of the N-glycosidic bond and as base excision repair (BER) intermediates. AP sites and their derivatives readily trap DNA-bound proteins, resulting in DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a15963618d8d81614d790051d7e4a1c0
https://doi.org/10.1093/nar/gkad423
https://doi.org/10.1093/nar/gkad423
Publikováno v:
Advances in experimental medicine and biology. 1241
A variety of endogenous and exogenous factors induce chemical and structural alterations in cellular DNA in addition to the errors occurring throughout DNA synthesis. These types of DNA damage are cytotoxic, miscoding or both and are believed to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d70a9014a9217a047c84a9c84027d10
https://pubmed.ncbi.nlm.nih.gov/32383117
https://pubmed.ncbi.nlm.nih.gov/32383117
Autor:
Nadezhda A Timofeyeva, Vladimir V Koval, Alexander A Ishchenko, Murat K Saparbaev, Olga S Fedorova
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24063 (2011)
Human apurinic/apyrimidinic endonuclease 1 (APE1) is a key enzyme in the base excision repair (BER) and nucleotide incision repair (NIR) pathways. We recently analyzed the conformational dynamics and kinetic mechanism of wild-type (wt) protein, in a
Externí odkaz:
https://doaj.org/article/eaf39bb850a04a9b8b246faf5e1f7764
Autor:
Peter R, Martin, Sophie, Couvé, Caroline, Zutterling, Mustafa S, Albelazi, Regina, Groisman, Bakhyt T, Matkarimov, Jason L, Parsons, Rhoderick H, Elder, Murat K, Saparbaev
Publikováno v:
Scientific Reports
Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked psor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4bca2f7bbcc17c2907ce762b7eddc8c
https://pubmed.ncbi.nlm.nih.gov/29234069
https://pubmed.ncbi.nlm.nih.gov/29234069
Autor:
Macé-Aimé, Gaëtane, Couvé, Sophie, Khassenov;, Bekbolat, Filippo Rosselli, Murat K. Saparbaev
Publikováno v:
Environmental & Molecular Mutagenesis; Jul2010, Vol. 51 Issue 6, p508-519, 12p
Autor:
Maria V. Rogacheva, Anastasia V. Bochenkova, Svetlana A. Kuznetsova, Murat K. Saparbaev, Alexander V. Nemukhin
Publikováno v:
Journal of Physical Chemistry B; Jan2007, Vol. 111 Issue 2, p432-438, 7p