Maternal exome analysis for the diagnosis of oocyte maturation defects and early embryonic developmental arrest

Autor: Antonio Capalbo, Silvia Buonaiuto, Matteo Figliuzzi, Gianluca Damaggio, Laura Girardi, Silvia Caroselli, Maurizio Poli, Cristina Patassini, Murat Cetinkaya, Beril Yuksel, Ajuna Azad, Marie Louise Grøndahl, Eva R. Hoffmann, Carlos Simón, Vincenza Colonna, Semra Kahraman

Publikováno v: Capalbo, A, Buonaiuto, S, Figliuzzi, M, Damaggio, G, Girardi, L, Caroselli, S, Poli, M, Patassini, C, Cetinkaya, M, Yuksel, B, Azad, A, Grøndahl, M L, Hoffmann, E R, Simón, C, Colonna, V & Kahraman, S 2022, ' Maternal exome analysis for the diagnosis of oocyte maturation defects and early embryonic developmental arrest ', Reproductive BioMedicine Online, vol. 45, no. 3, pp. 508-518 . https://doi.org/10.1016/j.rbmo.2022.05.009

Research question: Can a methodology be developed for case selection and whole-exome sequencing (WES) analysis of women who are infertile owing to recurrent oocyte maturation defects (OOMD) and/or preimplantation embryo lethality (PREMBL)? Design: Da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4b96cf80e77b432e92b7ebbffadd26
https://doi.org/10.1016/j.rbmo.2022.05.009

High rates of aneuploidy, mosaicism and abnormal morphokinetic development in cases with low sperm concentration

Autor: Mesut Yesil, Murat Cetinkaya, Y. Kumtepe, Cigdem Cinar Yapan, Hakan Yelke, Semra Kahraman, Mehmet Ali Tufekci, Yucel Sahin

Publikováno v: Journal of Assisted Reproduction and Genetics

Purpose The aim of our study was to evaluate the impact of severe male infertility (SMF) on the chromosomal status of embryos and any possible correlation between chromosomal status and embryo morphokinetics in younger women using data obtained from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6847f0e8c7717dfbba231cb565cfe2bf
https://doi.org/10.1007/s10815-019-01673-w

P–526 Incidence of mosaic embryos in day–6 blastocysts, may late blastulation predispose to mosaicism?

Autor: Murat Cetinkaya, Mehmet Ali Tufekci, Semra Kahraman, C Cina. Yapan

Publikováno v: Human Reproduction. 36

Study question May the mosaicism ratio be influenced by the time of blastulation in preimplantation genetic testing for aneuploidies (PGT-A)? Summary answer The mosaicism ratio is significantly higher in day–6 blastocysts when compared to day–5 w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc4926729cb2682629d4f18ed437be1e
https://doi.org/10.1093/humrep/deab130.525

O-202 Usage of laser during trophectoderm biopsy and its affect on PGT-A results and moscaism

Autor: Y. Kumtepe Colakoglu, Semra Kahraman, Murat Cetinkaya, Beril Yuksel, Hakan Yelke

Publikováno v: Human Reproduction. 36

Study question Does laser use during trophectoderm biopsy affect biopsy results on prehatching embryos with regard to mosaicism ? Summary answer According to our findings laser usage during trophectoderm biopsy increases mosaic results on next genera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63a869ef37a275d7a020ccfea390e8f6
https://doi.org/10.1093/humrep/deab128.013

EXCESSIVE FLUSHING MAY REDUCE IVF CYCLE CANCELLATIONS BY ENABLING EGG RETRIEVAL AND MAY PROVIDE POSITIVE OUTCOMES IN ONLY SINGLE FOLLICLE-DEVELOPED POOR RESPONDERS

Autor: Beril Yuksel, Semra Kahraman, Murat Cetinkaya, Melih Aygun, Yesim Kumtepe Colakoglu

Publikováno v: Fertility and Sterility. 116:e375

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7123c6b35804ed503dbeff2f599c26f1
https://doi.org/10.1016/j.fertnstert.2021.07.1008