Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Muralidharan Shanmugam"'
Autor:
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J. Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O. Johannissen, Colin W. Levy, Laura N. Jeffreys, Shaowei Zhang, Michiyo Sakuma, Jacques-Philippe Colletier, Sam Hay, Giorgio Schirò, Martin Weik, Nigel S. Scrutton, David Leys
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid biosynthesis. How light-triggered cleavage of the B12 Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear. Here, a seri
Externí odkaz:
https://doaj.org/article/001606f7b0874be9a4255441eb03bd98
Autor:
Satya Prathyusha Bhamidimarri, Tessa R Young, Muralidharan Shanmugam, Sandra Soderholm, Arnaud Baslé, Dirk Bumann, Bert van den Berg
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001446 (2021)
Copper, while toxic in excess, is an essential micronutrient in all kingdoms of life due to its essential role in the structure and function of many proteins. Proteins mediating ionic copper import have been characterised in detail for eukaryotes, bu
Externí odkaz:
https://doaj.org/article/af8157dec86e4154a2b6cbf9055eb196
Publikováno v:
The FEBS journal.
Rieske monooxygenases undertake complex catalysis integral to marine, terrestrial and human gut-ecosystems. Group-I to IV Rieske monooxygenases accept aromatic substrates and have well characterised catalytic mechanisms. Nascent to our understanding
Autor:
Andrew M. Stewart, Muralidharan Shanmugam, Roger J. Kutta, Nigel S. Scrutton, Janet E. Lovett, Sam Hay
Publikováno v:
Biochemistry. 61(17)
A.M.S. received Early Stage Research Funding from the European Union’s Seventh Framework Programme FP-7-PEOPLE-2013-ITN through the “MAGnetic Innovation in Catalysis” (MAGIC) Initial Training Network (grant agreement no. 606831). Part of this w
Autor:
Craig M. Robertson, Eric J. L. McInnes, Muralidharan Shanmugam, Renpeng Guan, Jianliang Xiao, Adam Brookfield, Elliot L. Bennett, Zhiliang Huang
Publikováno v:
Journal of the American Chemical Society
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Huang, Z, Guan, R, Shanmugam, M, Bennett, E L, Robertson, C M, Brookfield, A, McInnes, E J L & Xiao, J 2021, ' Oxidative Cleavage of Alkenes by O-2 with a Non-Heme Manganese Catalyst ', Journal of the American Chemical Society, vol. 143, no. 26, pp. 10005-10013 . https://doi.org/10.1021/jacs.1c05757
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Huang, Z, Guan, R, Shanmugam, M, Bennett, E L, Robertson, C M, Brookfield, A, McInnes, E J L & Xiao, J 2021, ' Oxidative Cleavage of Alkenes by O-2 with a Non-Heme Manganese Catalyst ', Journal of the American Chemical Society, vol. 143, no. 26, pp. 10005-10013 . https://doi.org/10.1021/jacs.1c05757
The oxidative cleavage of C═C double bonds with molecular oxygen to produce carbonyl compounds is an important transformation in chemical and pharmaceutical synthesis. In nature, enzymes containing the first-row transition metals, particularly heme
Autor:
Tobias M. Hedison, Andreea I. Iorgu, Donato Calabrese, Derren J. Heyes, Muralidharan Shanmugam, Nigel S. Scrutton
Publikováno v:
Hedison, T M, Iorgu, A I, Calabrese, D, Heyes, D J, Shanmugam, M & Scrutton, N S 2022, ' Solution-State Inter-Copper Distribution of Redox Partner-Linked Copper Nitrite Reductases: A Pulsed Electron–Electron Double Resonance Spectroscopy Study ', The journal of physical chemistry letters, pp. 6927-6934 . https://doi.org/10.1021/acs.jpclett.2c01584
Copper nitrite reductases (CuNiRs) catalyze the reduction of nitrite to form nitric oxide. In recent years, new classes of redox partner linked CuNiRs have been isolated and characterized by crystallographic techniques. Solution-state biophysical stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce2ea17249a1a5481531892ed3eb160
https://research.manchester.ac.uk/en/publications/b1c27d29-3fe3-4ca5-9681-635a4ef7147d
https://research.manchester.ac.uk/en/publications/b1c27d29-3fe3-4ca5-9681-635a4ef7147d
Autor:
Samuel L. Rose, Seiki Baba, Hideo Okumura, Svetlana V. Antonyuk, Daisuke Sasaki, Tobias M. Hedison, Muralidharan Shanmugam, Derren J. Heyes, Nigel S. Scrutton, Takashi Kumasaka, Takehiko Tosha, Robert R. Eady, Masaki Yamamoto, S. Samar Hasnain
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(30)
Many enzymes utilize redox-coupled centers for performing catalysis where these centers are used to control and regulate the transfer of electrons required for catalysis, whose untimely delivery can lead to a state incapable of binding the substrate,
Autor:
Zhiliang Huang, Muralidharan Shanmugam, Zhao Liu, Adam Brookfield, Elliot L. Bennett, Renpeng Guan, David E. Vega Herrera, Jose A. Lopez-Sanchez, Anna G. Slater, Eric J. L. McInnes, Xiaotian Qi, Jianliang Xiao
Publikováno v:
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Huang, Z, Shanmugam, M, Liu, Z, Brookfield, A, Bennett, E L, Guan, R, Vega Herrera, D E, Lopez-Sanchez, J A & Slater, A G 2022, ' Chemical Recycling of Polystyrene to Valuable Chemicals via Selective Acid-Catalyzed Aerobic Oxidation under Visible Light ', J. Am. Chem. Soc., vol. 144, no. 14, 144, pp. 6532-6542 . https://doi.org/10.1021/jacs.2c01410
Huang, Z, Shanmugam, M, Liu, Z, Brookfield, A, Bennett, E L, Guan, R, Vega Herrera, D E, Lopez-Sanchez, J A & Slater, A G 2022, ' Chemical Recycling of Polystyrene to Valuable Chemicals via Selective Acid-Catalyzed Aerobic Oxidation under Visible Light ', J. Am. Chem. Soc., vol. 144, no. 14, 144, pp. 6532-6542 . https://doi.org/10.1021/jacs.2c01410
Chemical recycling is one of the most promising technologies that could contribute to circular economy targets by providing solutions to plastic waste; however, it is still at an early stage of development. In this work, we describe the first light-d
Autor:
Jingming Zhao, Ying Zhuo, Daniel Diaz, Muralidharan Shanmugam, Abbey Telfer, Peter Lindley, Daniel Kracher, Takahiro Hayashi, Lisa Seibt, Florence Hardy, Oliver Manners, Tobias Hendison, Katherine Hollywood, Sofia Diaz-Moreno, Nigel Scrutton, Morten Tovborg, Gideon Davies, Paul Walton, Derren Heyes, Anthony Green
Oxygenase enzymes generate reactive intermediates at their active sites to effect controlled functionalizations of inert C–H bonds in substrates, such as in the enzymatic conversion of methane to methanol. To be viable catalysts, however, these enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f0283a9a945ad6f5da266485dfe2c6a
https://doi.org/10.21203/rs.3.rs-1350705/v1
https://doi.org/10.21203/rs.3.rs-1350705/v1