Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Murali Ramanathan"'
Autor:
Murali Ramanathan
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 5, Pp 1347-1358 (2024)
Abstract Objective To model interdependencies of serum neurofilament light chain (sNfL), a clinically useful biomarker of axonal injury in neurological diseases, with demographic, anthropometric, physiological, and disease biomarkers in the United St
Externí odkaz:
https://doaj.org/article/5429cf59875145e1a32d11d03d14303f
Autor:
Kian Jalaleddini, Dejan Jakimovski, Anisha Keshavan, Shannon McCurdy, Kelly Leyden, Ferhan Qureshi, Atiyeh Ghoreyshi, Niels Bergsland, Michael G. Dwyer, Murali Ramanathan, Bianca Weinstock‐Guttman, Ralph HB Benedict, Robert Zivadinov
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 729-743 (2024)
Abstract Background A quantitative measurement of serum proteome biomarkers that would associate with disease progression endpoints can provide risk stratification for persons with multiple sclerosis (PwMS) and supplement the clinical decision‐maki
Externí odkaz:
https://doaj.org/article/6608227ad3b546a09947ed62760a565f
Autor:
Flora Qu, Ming Zhang, Bianca Weinstock-Guttman, Robert Zivadinov, Jun Qu, Xiaoyu Zhu, Murali Ramanathan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Quantitative analysis of the biologically-active metabolites of vitamin D (VitD), which are crucial in regulating various physiological and pathological processes, is important for clinical investigations. Liquid chromatography-tandem mass s
Externí odkaz:
https://doaj.org/article/6ada20df2d0f4664a3dc10f8a1587572
Autor:
Dejan Jakimovski, Ryu P. Dorn, Megan Del Regno, Alexander Bartnik, Niels Bergsland, Murali Ramanathan, Michael G. Dwyer, Ralph H. B. Benedict, Robert Zivadinov, Kinga Szigeti
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionCHRFAM7A, a uniquely human fusion gene, has been associated with neuropsychiatric disorders including Alzheimer’s disease, schizophrenia, anxiety, and attention deficit disorder. Understanding the physiological function of CHRFAM7A in t
Externí odkaz:
https://doaj.org/article/493eeae30ec648188dbf9fbac2508561
Autor:
Thomas Guttuso, Jr., Rachel Shepherd, Luciana Frick, M. Laura Feltri, Valerie Frerichs, Murali Ramanathan, Robert Zivadinov, Niels Bergsland
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 429-434 (2023)
Background: Lithium has a wide range of neuroprotective actions, has been effective in Parkinson’s disease (PD) animal models and may account for the decreased risk of PD in smokers. Methods: This open-label pilot clinical trial randomized 16 PD pa
Externí odkaz:
https://doaj.org/article/392a8022eecb44df957757f093863e67
Autor:
Pooja Veerareddy, Nhi Dao, Jungmi W. Yun, Karen Y. Stokes, Elizabeth Disbrow, Christopher G. Kevil, Urska Cvek, Marjan Trutschl, Philip Kilgore, Murali Ramanathan, Robert Zivadinov, Jonathan S. Alexander
Publikováno v:
Pathophysiology, Vol 29, Iss 3, Pp 570-582 (2022)
Multiple sclerosis (MS) is a leading cause of neurodegenerative disability in younger individuals. When diagnosed early, MS can be managed more effectively, stabilizing clinical symptoms and delaying disease progression. The identification of specifi
Externí odkaz:
https://doaj.org/article/1cb7616bb991475baf212b1767a2ab51
Autor:
Dejan Jakimovski, Robert Zivadinov, Laura Pelizzari, Cynthia Dunne-Jaffe, Richard W. Browne, Niels Bergsland, Michael G. Dwyer, Bianca Weinstock-Guttman, Murali Ramanathan
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Multiple sclerosis (MS) studies suggest greater cardiovascular disease burden and disturbances in the cholesterol pathways1,2 The potential impact of oxidized cholesterol molecules (oxysterols) on MS is emerging (Figure 1).3 Objective:
Externí odkaz:
https://doaj.org/article/c95b5dcabb08419fb3fb6a14aff1a1e9
Autor:
Dejan Jakimovski, Brianna L. Gibney, Karen Marr, Deepa P. Ramasamy, Michael G. Dwyer, Niels Bergsland, Bianca Weinstock-Guttman, Murali Ramanathan, Robert Zivadinov
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Hypoperfusion, vascular pathology, and cardiovascular risk factors are associated with disease severity in multiple sclerosis (MS).1,2 In particular, the total cerebral arterial blood flow (CABF), measured as a sum of all arterial flow in
Externí odkaz:
https://doaj.org/article/3598483dedea44919d5a7db28525d01c
Autor:
Robert Parambi, Nicole Ziliotto, Francesco Bernardi, Marcello Baroni, Richard W Browne, Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov, Murali Ramanathan
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 1, Iss 3 (2022)
The individual roles of cholesterol pathway biomarkers (CPB) and hemostasis inhibitors with neuroimaging outcomes were previously investigated in multiple sclerosis (MS). The purpose of this extension study was to investigate potential crosstalk betw
Externí odkaz:
https://doaj.org/article/c223b3f128234d92a323a4b4a777f9df
Autor:
Dejan Jakimovski, Jens Kuhle, Murali Ramanathan, Christian Barro, Davorka Tomic, Jesper Hagemeier, Harald Kropshofer, Niels Bergsland, David Leppert, Michael G. Dwyer, Zuzanna Michalak, Ralph H. B. Benedict, Bianca Weinstock‐Guttman, Robert Zivadinov
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1757-1770 (2019)
Abstract Background Gray matter (GM) pathology is closely associated with physical and cognitive impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light chain (sNfL) levels are related to MS disease activity and pro
Externí odkaz:
https://doaj.org/article/fa2395b281e14fb8bdb3a64daa5654e4