Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Murali K. Levadala"'
Autor:
Justin W. Hicks, Frank J. Femia, John W. Babich, Chitra Sundararajan, Shawn Hillier, Craig Zimmerman, Murali K. Levadala, John F. Valliant, Sangeeta Ray Banerjee, Jon Zubieta, Kevin P. Maresca, John Joyal, William C. Eckelman
Publikováno v:
Bioconjugate Chemistry. 20:1625-1633
Technetium tricarbonyl chemistry has been a subject of interest in radiopharmaceutical development over the past decade. Despite the extensive work done on developing chelates for Tc(I), a rigorous investigation of the impact of changing donor groups
Autor:
Murali K. Levadala, Karin A. Stephenson, Sangeeta Ray Banerjee, John W. Babich, John F. Valliant, Oyebola O. Sogbein, Nicole McFarlane, Jon Zubieta, Douglas R. Boreham, Kevin P. Maresca
Publikováno v:
Bioconjugate Chemistry. 16:1189-1195
A new solid-phase synthetic methodology was developed that enables libraries of peptide-based Tc(I)/Re(I) radiopharmaceuticals to be prepared using a conventional automated peptide synthesizer. Through the use of a tridentate ligand derived from N-al
Publikováno v:
Inorganica Chimica Acta. 357:1499-1516
Arylpiperazines, XC6H4N(CH2CH2)2NH, are readily alkylated to give the N-alkylpiperazines of the type XC6H4N(CH2CH2)2N(CH2)nNH2. The amine functions of these derivatives are in turn easily subjected to mono- or dialkylation to provide potentially trid
Publikováno v:
Inorganic Chemistry Communications. 6:1099-1103
The reactions of potentially tridentate ligands, derived from N-arylpiperazines, with [NEt4]2[Re(CO)3Br3] have been investigated. The compounds [Re(CO)3{NC5H4CH2N(H) CH2CH2–Fphenpip}]Br (1Br), [Re(CO)3{(NC5H4CH2)2NCH2CH2CH2–CH3OphenpipH}]Br2 · 2
Autor:
Lihui Wei, John F. Valliant, John W. Babich, Murali K. Levadala, Neva Lazarova, Sangeeta Ray Banerjee, Jon Zubieta, Karin A. Stephenson, Kevin P. Maresca
Publikováno v:
Inorganic Chemistry. 41:6417-6425
Autor:
Murali K. Levadala, Karin A. Stephenson, John F. Valliant, John W. Babich, Charles J. O'Connor, Neva Lazarova, Vladimir Golub, Lihui Wei, Jon Zubieta, Sangeeta Ray Banerjee
Publikováno v:
Inorganic Chemistry. 41:5795-5802
The reactions of the Re(V) starting material [ReO(PPh(3))(2)Cl(3)] with ligands of the type XN(Y)Z [X = Y = 2-pyridylmethyl, Z = -CH(2)CO(2)Et (L(1)Et), -CH(2)CH(2)CO(2)Et (L(2)Et), -CH(2)CH(2)CH(2)CH(2)CH(NHCO(2)Bu(t))CO(2)H (L(3)H); X = 2-pyridylme
Publikováno v:
ChemInform. 36
A family of effective bifunctional chelators for techne- tium- and rhenium-based radiopharmaceuticals was conveniently synthesized in high yields through direct reductive N-alkylations of amino acids and their analogues with aldehydes, using NaBH(OAc
Autor:
Lorna A. Ryan, Kevin P. Maresca, John W. Babich, John F. Valliant, Sangeeta Ray Banerjee, Nicole McFarlane, Linda Taggart, Douglas R. Boreham, Jon Zubieta, Murali K. Levadala, Karin A. Stephenson
Publikováno v:
Bioconjugate chemistry. 15(1)
A tridentate single amino acid chelate (SAAC) derived from N-alpha-Fmoc-l-lysine was incorporated within a short peptide sequence using an automated peptide synthesizer. Novel derivatives of the chemotactic peptide fMLF were prepared such that the SA
Autor:
Sangeeta Ray, Banerjee, Murali K, Levadala, Neva, Lazarova, Lihui, Wei, John F, Valliant, Karin A, Stephenson, John W, Babich, Kevin P, Maresca, Jon, Zubieta
Publikováno v:
Inorganic chemistry. 41(24)
The reactions of a series of potentially tridentate ligands, derived from single amino acids or amino acid analogues, with [NEt(4)](2)[ReBr(3)(CO)(3)] have been investigated. The model compounds [Re(CO)(3)Br[(2-pyridylmethyl)NH(2)]] (1) and [Re(CO)(3
Autor:
Travis R. Besanger, Murali K. Levadala, Douglas R. Boreham, Karin A. Stephenson, Oyebola O. Sogbein, John W. Babich, Nicole McFarlane, Sangeeta Ray Banerjee, Jennifer A. Lemon, John D. Brennan, John F. Valliant, Jon Zubieta, Kevin P. Maresca
Publikováno v:
Journal of the American Chemical Society. 126:8598-8599
A bifunctional ligand that is capable of forming Re and 99mTc complexes as complementary fluorescent and radioactive probes was developed. The tridentate bis(quinoline) amine ligand, which is referred to as the SAACQ system, was prepared in a single