Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Murali K. Bollepalli"'
A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
Autor:
Jinguo Cao, Murali K. Bollepalli, Yuhui Hu, Jin Zhang, Qiang Li, Hongmei Li, Hua Chang, Feng Xiao, Roger C. Hardie, Yikang S. Rong, Wen Hu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 363-371 (2018)
Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong l
Externí odkaz:
https://doaj.org/article/5e1c027e9e414dabbde1af7bf92904f3
Autor:
An eDau, Uwe eFriederich, Sidhartha eDongre, Xiaofeng eLi, Murali K. Bollepalli, Roger Clayton Hardie, Mikko eJuusola
Publikováno v:
Frontiers in Neural Circuits, Vol 10 (2016)
Synaptic feedback from interneurons to photoreceptors can help to optimize visual information flow by balancing its allocation on retinal pathways under changing light conditions. But little is known about how this critical network operation is regul
Externí odkaz:
https://doaj.org/article/131d5de0bbbe4eb38f66bc9a1c08763d
Autor:
Sidhartha Dongre, Mikko Juusola, David Jaciuch, Xiaofeng Li, Diana Rien, Murali K. Bollepalli, Brian Chu, Zhuoyi Song, Lei Zheng, Roger C. Hardie, Patrick J. Dolph, Florence Blanchard, Anton Nikolaev, Ahmad N. Abou Tayoun, An Dau
Publikováno v:
The Journal of Neuroscience. 39:7132-7154
Ca2+-activated K+ channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discover ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503dbf41918ebb73eb20a4eb02b777f5
https://doi.org/10.1523/jneurosci.3213-18.2019
https://doi.org/10.1523/jneurosci.3213-18.2019
A Single Residue Mutation in the Gαq Subunit of the G Protein Complex Causes Blindness in Drosophila
Autor:
Jinguo Cao, Qiang Li, Murali K. Bollepalli, Hua Chang, Feng Xiao, Yikang S Rong, Hongmei Li, Jin Zhang, Wen Hu, Roger C. Hardie, Yuhui Hu
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 363-371 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 363-371 (2018)
Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gαq is not clear since animals with previously reported strong l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a733b861f41ea483b298b4e1cf5a0d
http://europepmc.org/articles/PMC5765363
http://europepmc.org/articles/PMC5765363
Autor:
Xiaofeng, Li, Ahmad, Abou Tayoun, Zhuoyi, Song, An, Dau, Diana, Rien, David, Jaciuch, Sidhartha, Dongre, Florence, Blanchard, Anton, Nikolaev, Lei, Zheng, Murali K, Bollepalli, Brian, Chu, Roger C, Hardie, Patrick J, Dolph, Mikko, Juusola
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(36)
Ca(2+)-activated K(+) channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::387f792ea26d7119e3240fba7f7c2534
https://pubmed.ncbi.nlm.nih.gov/31350259
https://pubmed.ncbi.nlm.nih.gov/31350259
Autor:
Samuel Long, Murali K. Bollepalli, Sabrina Asteriti, Roger C. Hardie, Julie Tan, Julie A. Brill, Che-Hsiung Liu
Publikováno v:
Journal of Cell Science.
Phototransduction in Drosophila is mediated by phospholipase C dependent hydrolysis of PIP2, and is an important model for phosphoinositide signalling. Although generally assumed to operate by generic machinery conserved from yeast to mammals, some k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a505cc4eb1409f2a82d89d2c3e5136
https://doi.org/10.1242/jcs.214478
https://doi.org/10.1242/jcs.214478
Publikováno v:
eNeuro
Drosophila phototransduction is mediated by phospholipase C, leading to activation of transient receptor potential (TRP) and TRP-like (TRPL) channels by mechanisms that are unresolved. A role for InsP3 receptors (IP3Rs) had been excluded because IP3R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::282d1eb83f81c1f25c1f1964f69cd208
https://pubmed.ncbi.nlm.nih.gov/28660247
https://pubmed.ncbi.nlm.nih.gov/28660247
Autor:
Ehsan Nematian-Ardestani, Murali K. Bollepalli, Thomas Baukrowitz, Mark S.P. Sansom, Lijun Shang, Philip W. Fowler, Stephen J. Tucker, Markus Rapedius
Publikováno v:
Channels
In a previous study we identified an extensive gating network within the inwardly rectifying Kir1.1 (ROMK) channel by combining systematic scanning mutagenesis and functional analysis with structural models of the channel in the closed, pre-open and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff7d4bbb9ad55aa7b38e5da4d3e6dd6
https://doi.org/10.4161/19336950.2014.962371
https://doi.org/10.4161/19336950.2014.962371
Autor:
Thomas Baukrowitz, Gunter Erhlich, Hariolf Fritzenschaft, Stephen J. Tucker, Murali K. Bollepalli, Paula L. Piechotta, Mark S.P. Sansom, Markus Rapedius, Isabelle Andres-Enguix, Phillip J. Stansfeld, Niels Decher
Publikováno v:
The EMBO Journal. 30:3607-3619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fccd3dbea9482f65a5597868ecfafbcc
https://doi.org/10.1038/emboj.2011.268
https://doi.org/10.1038/emboj.2011.268
Autor:
Anne K. Streit, Jürgen Daut, Vijay Renigunta, Magdalena Walecki, Michael F. Netter, Niels Decher, Phillip J. Stansfeld, Mark S.P. Sansom, Susanne Rinné, Regina Preisig-Müller, Franca Kempf, Thomas Baukrowitz, Murali K. Bollepalli
Publikováno v:
The Journal of Biological Chemistry
Two-pore domain potassium (K(2P)) channels play a key role in setting the membrane potential of excitable cells. Despite their role as putative targets for drugs and general anesthetics, little is known about the structure and the drug binding site o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ebe55df225240ff970eef6128c3f50
https://doi.org/10.1074/jbc.m111.227884
https://doi.org/10.1074/jbc.m111.227884